RNA Sequencing: Technologies and Global Markets
Market Research Report I 2024-09-20 I 166 Pages I BCC Research
Description
Report Scope:
This research report covers the global market for RNA sequencing. It incorporates an in-depth analysis of the RNA sequencing market, including market estimates and trends through 2029. For this analysis, the market has been segmented based on products, technologies, applications, end users and regions. In terms of geographical region, the market is divided into four regions: North America, Europe, Asia-Pacific and Rest of the World (RoW). For market estimates, data has been provided for the base year 2023, with forecasts for 2024 through 2029.
This report also examines strategies and collaborations, discusses the regulatory landscape and analyzes macroeconomic factors when considering new technologies, the industry's growing competition and changing customer needs. It also includes various analytical frameworks, such as ESG analysis, competitive analysis and strategic recommendations, that will help companies operating within this market devise their strategic plan of action.
Report Includes:
- 65 data tables and 57 additional tables
- A review of the global market and technologies for RNA sequencing
- Analyses of the global market trends, with data from 2021-2023, estimates for 2024, and projections of compound annual growth rates (CAGRs) through 2029
- Evaluation of the overall market for RNA sequencing, and corresponding market share analysis by product, technology, application, end-user and region
- Discussion of recent RNA sequencing approaches such as next-generation sequencing (NGS) technology, single nucleotide polymorphism (SNP) discovery, RNA editing, and Sanger sequencing technology
- Discussions of the market dynamics, opportunities and challenges, as well as emerging technologies
- Analysis of the regulatory landscape and macroeconomic factors impacting the market
- Coverage of the most recent approvals, recalls, safety alerts and clinical trials
- Overview of the sustainability trends and ESG developments in the industry, with emphasis on the ESG practices followed by leading companies, their ESG ratings, and consumer attitudes
- Competitive intelligence, including companies' market shares, recent M&A activity and venture funding
- Profiles of the leading companies, including Thermo Fisher Scientific Inc., Agilent Technologies Inc., Illumina Inc., and Qiagen
Executive Summary
Summary:
A novel technique in the genetic diagnostic lab, RNA sequencing, or RNA-Seq, is made feasible by the development of high-throughput, low-cost, next-generation sequencing technology. In the past, RNA research was restricted to measuring the expression of certain genes and detecting gene rearrangements using microarray technologies. A growing number of clinical samples are using RNA-Seq to detect qualitative and quantitative changes in RNA expression throughout the genome. It is being utilized as a supplement to whole-genome and diagnostic exome sequencing.
RNA sequencing technology uses next-generation sequencing (NGS) to assess the continuously changing cellular transcriptome by revealing the presence and quantity of RNA in a biological sample at a certain time. It facilitates the examination of alternatively spliced transcripts, post-transcriptional modifications, gene fusion, mutations/SNPs and changes in gene expression over time, as well as variations in gene expression in different populations or therapeutic regimens. The RNA sequencing market is set to gain momentum due to the increasing adoption of NGS-based RNA technologies and products in various fields, including biomedical research and pharmaceutical development, coupled with increasing research investments, applications across multiple sectors and collaborative initiatives as well as acceleratingdevelopments in precision medicine.
Life sciences laboratories are increasingly shifting toward using high-throughput RNA sequencing as a standard method for transcript identification and differential gene expression research. Advances in next-generation sequencing (NGS) technology that have significantly reduced sequencing costs have made it possible for most scientists to afford to use this powerful approach. The final stage of an RNASeq experiment is data analysis. Here, selecting the appropriate software toolbox is essential to carrying out the required quality checks, resolving biases and, ultimately, providing answers to the study's concerns. This enhances the accuracy of experimental results, leading to the significant adoption of such technologies in the market.
Table of Contents
Chapter 1 Executive Summary
Market Outlook
Scope of Report
Market Summary
Chapter 2 Market Overview
Overview
Technology Background
Transcriptomics Technologies
RNA Sequencing for Transcriptomics
RNA-Seq Experimental Workflow
RNA-Seq Workflow Considerations
Steps to Select the Right Platform for RNA Sequencing
Regulatory Landscape
Growth Strategy Recommendations
Chapter 3 Market Dynamics
Market Dynamics
Market Drivers
Rapid Advances in Data Analysis Capabilities
Favorable Funding Scenario for Genomics and Biomedical Research Activities
Decline in the Prices of Genome Sequencing
Growing Prevalence of Cancer Generating Demand for Personalized Treatments
Market Restraints
Lack of Data Standardization
Cost vs. Coverage Challenges
Market Opportunities
Harnessing Blockchain and Cloud Computing Technologies
Technological Advances in RNA Isolation and Extraction Processes
Chapter 4 Emerging Technologies and Developments
Single-Cell RNA Sequencing
Other Emerging Single-Cell Technologies
Chapter 5 Market Segmentation Analysis
Key Market Trends
Segmentation Breakdown
Global Market for RNA Sequencing by Product
Instruments
Tools and Reagents
Software and Services
Global Market for RNA Sequencing by Technology
Sequencing by Synthesis
Ion Torrent Semiconductor Sequencing
Single-Molecule Real-Time Sequencing
Nanopore Sequencing
Global Market for RNA Sequencing by Application
Expression Profiling Analysis
Small RNA Sequencing
De Novo Transcriptome Assembly
Variant Calling and Transcriptome Epigenetics
Global Market for RNA Sequencing by End User
Academic Research Organizations
Pharmaceutical and Biotechnology Companies
Clinical and Hospital Laboratories
Other End Users
Geographic Breakdown
Global RNA Sequencing Market by Region
North America
Europe
Asia-Pacific
Rest of the World
Chapter 6 Competitive Intelligence
Overview
Ranking of Leading Market Players
Key Strategies Adopted by Players
Collaborations and Agreements
New Product Launches
Partnerships
Expansions
Mergers and Acquisitions
The Role of CROs in RNA Sequencing Data Generation
Leading RNA Sequencing Service Providers
Chapter 7 Sustainability in RNA Sequencing Market: ESG Perspective
Introduction to ESG
ESG Performance in the Market
ESG Practices in the RNA Sequencing Industry
Environmental Performance
Social Performance
Governance Performance
Concluding Remarks from BCC Research
Chapter 8 Appendix
Methodology
References
Acronyms
Company Profiles
10X GENOMICS
AGILENT TECHNOLOGIES INC.
BECKMAN COULTER INC. (SUBSIDIARY OF DANAHER CORP.)
BIO-RAD LABORATORIES INC.
BGI
F. HOFFMANN-LA ROCHE LTD.
ILLUMINA INC.
INTEGRATED DNA TECHNOLOGIES INC.
MICROSYNTH AG
OXFORD NANOPORE TECHNOLOGIES PLC.
QIAGEN
REVVITY
STANDARD BIOTOOLS
THERMO FISHER SCIENTIFIC INC.
List of Tables
Summary Table A : Global Market for RNA Sequencing, by Product, Through 2029
Summary Table B : Global Market for RNA Sequencing, by Technology, Through 2029
Table 1 : Types of RNAs in Cells
Table 2 : Comparison of Transcriptomics Methods
Table 3 : Functional Elements in Sequencing Adapters
Table 4 : Publicly Available Transcriptomics Data in the Cancer Research Field
Table 5 : Overview of Illumina's Sequencing Instruments
Table 6 : Global Market for RNA Sequencing for Instruments, by Region, Through 2029
Table 7 : Global Market for RNA Sequencing for Tools and Reagents, by Region, Through 2029
Table 8 : rRNA Depletion Kits
Table 9 : mRNA Enrichment Kits
Table 10 : Global Market for RNA Sequencing Sample Preparation for Tools & Reagents, by Region, Through 2029
Table 11 : RNA Sequencing Kits for Illumina Platform
Table 12 : Thermo Fisher RNA Sequencing Products for Ion Torrent
Table 13 : Thermo Fisher's RNA Sequencing Library Prep Kits for SOLiD
Table 14 : Global Market for RNA Sequencing Library Preparation for Tools and Reagents, by Region, Through 2029
Table 15 : Cloud Computing Providers for Genomics/RNA-Seq
Table 16 : Global Market for RNA Sequencing for Software and Services, by Region, Through 2029
Table 17 : RNA Sequencing Applications on Illumina Platforms
Table 18 : Global Market for RNA Sequencing for Sequencing by Synthesis, by Region, Through 2029
Table 19 : RNA Sequencing Applications on Ion Torrent Systems
Table 20 : Global Market for RNA Sequencing for Ion Torrent Semiconductor, by Region, Through 2029
Table 21 : PacBio RNA-Seq Applications
Table 22 : PacBio RNA-Seq Workflow
Table 23 : Global Market for RNA Sequencing for Single-Molecule Real-Time Sequencing, by Region, Through 2029
Table 24 : Global Market for RNA Sequencing for Nanopore Sequencing, by Region, Through 2029
Table 25 : Global Market for RNA Sequencing for Expression Profiling Analysis, by Region, Through 2029
Table 26 : Small RNA-Seq on Illumina Platforms
Table 27 : Global Market for RNA Sequencing for Small RNA Sequencing, by Region, Through 2029
Table 28 : Global Market for RNA Sequencing for De Novo Transcriptome Assembly, by Region, Through 2029
Table 29 : Global Market for RNA Sequencing for Variant Calling & Transcriptome Epigenetics, by Region, Through 2029
Table 30 : Global Market for RNA Sequencing for Academic Research Organizations, by Region, Through 2029
Table 31 : Global Market for RNA Sequencing for Pharmaceutical and Biotechnology Companies, by Region, Through 2029
Table 32 : Global Market for RNA Sequencing for Clinical and Hospital Laboratories, by Region, Through 2029
Table 33 : Global Market for RNA Sequencing for Other End Users, by Region, Through 2029
Table 34 : Global Market for RNA Sequencing, by Region, Through 2029
Table 35 : North American Market for RNA Sequencing, by Product, Through 2029
Table 36 : North American Market for RNA Sequencing for Tools & Reagents, by Type, Through 2029
Table 37 : North American Market for RNA Sequencing, by Technology, Through 2029
Table 38 : North American Market for RNA Sequencing, by Application, Through 2029
Table 39 : North American Market for RNA Sequencing, by End User, Through 2029
Table 40 : Research Initiatives Focused on Personalized Medicine in Europe
Table 41 : European Market for RNA Sequencing, by Product, Through 2029
Table 42 : European Market for RNA Sequencing for Tools and Reagents, by Type, Through 2029
Table 43 : European Market for RNA Sequencing, by Technology, Through 2029
Table 44 : European Market for RNA Sequencing, by Application, Through 2029
Table 45 : European Market for RNA Sequencing, by End User, Through 2029
Table 46 : Asia-Pacific Market for RNA Sequencing, by Product, Through 2029
Table 47 : Asia-Pacific Market for RNA Sequencing for Tools and Reagents, by Type, Through 2029
Table 48 : Asia-Pacific Market for RNA Sequencing, by Technology, Through 2029
Table 49 : Asia-Pacific Market for RNA Sequencing, by Application, Through 2029
Table 50 : Asia-Pacific Market for RNA Sequencing, by End User, Through 2029
Table 51 : RoW Market for RNA Sequencing, by Product, Through 2029
Table 52 : RoW Market for RNA Sequencing for Tools and Reagents, by Type, Through 2029
Table 53 : RoW Market for RNA Sequencing, by Technology, Through 2029
Table 54 : RoW Market for RNA Sequencing, by Application, Through 2029
Table 55 : RoW Market for RNA Sequencing, by End User, Through 2029
Table 56 : Leading Players in RNA Sequencing Market, 2023
Table 57 : Collaborations and Agreements in the RNA Sequencing Market, 2021-2024
Table 58 : New Product Launches in the RNA Sequencing Market, 2021-2024
Table 59 : Partnerships in the RNA Sequencing Market, 2022-2024
Table 60 : Expansions in the RNA Sequencing Market, 2020-2024
Table 61 : Mergers and Acquisitions in the RNA Sequencing Market, 2020-2024
Table 62 : Leading RNA Sequencing Service Providers
Table 63 : Key Focus Areas in ESG Metrics
Table 64 : Environmental Performance Initiatives in the RNA Sequencing Market
Table 65 : Social Performance Initiatives in RNA Sequencing Market
Table 66 : Governance Performance Initiatives in RNA Sequencing Market
Table 67 : ESG Rankings for Key Players in RNA Sequencing Market, 2024*
Table 68 : Acronyms Used in this Report
Table 69 : 10x Genomics: Company Snapshot
Table 70 : 10x Genomics: Financial Performance, FY 2022 and 2023
Table 71 : 10x Genomics: Product Portfolio
Table 72 : 10x Genomics: News/Key Developments, 2022 and 2023
Table 73 : Agilent Technologies Inc.: Company Snapshot
Table 74 : Agilent Technologies Inc.: Financial Performance, FY 2022 and 2023
Table 75 : Agilent Technologies Inc.: Product and Services Portfolio
Table 76 : Agilent Technologies Inc.: News/Key Developments, 2021-2023
Table 77 : Beckman Coulter Inc. (Subsidiary of Danaher Corp.): Company Snapshot
Table 78 : Beckman Coulter Inc. (Subsidiary of Danaher Corp.): Product Portfolio
Table 79 : Beckman Coulter Inc. (Subsidiary of Danaher Corp.): News/Key Developments, 2022-2024
Table 80 : Bio-Rad Laboratories Inc.: Company Snapshot
Table 81 : Bio-Rad Laboratories Inc.: Financial Performance, FY 2022 and 2023
Table 82 : Bio-Rad Laboratories Inc.: Product Portfolio
Table 83 : Bio-Rad Laboratories Inc.: News/Key Developments, 2022-2024
Table 84 : BGI: Company Snapshot
Table 85 : BGI: Product & Services Portfolio
Table 86 : BGI: News/Key Developments, 2024
Table 87 : F. Hoffmann-La Roche Ltd.: Company Snapshot
Table 88 : F. Hoffman-La Roche Ltd.: Financial Performance, FY 2022 and 2023
Table 89 : F. Hoffman-La Roche Ltd.: Product Portfolio
Table 90 : F. Hoffman-La Roche Ltd.: News/Key Developments, 2021 and 2022
Table 91 : Illumina Inc.: Company Snapshot
Table 92 : Illumina Inc.: Financial Performance, FY 2022 and 2023
Table 93 : Illumina Inc.: Product Portfolio
Table 94 : Illumina Inc.: News/Key Developments, 2022-2024
Table 95 : Integrated DNA Technologies Inc.: Company Snapshot
Table 96 : Integrated DNA Technologies Inc.: Product & Services Portfolio
Table 97 : Integrated DNA Technologies Inc.: News/Key Developments, 2021-2024
Table 98 : Microsynth AG: Company Snapshot
Table 99 : Microsynth AG: Product & Services Portfolio
Table 100 : Microsynth AG: News/Key Developments, 2022
Table 101 : Oxford Nanopore Technologies plc.: Company Snapshot
Table 102 : Oxford Nanopore Technologies plc.: Financial Performance, FY 2022 and 2023
Table 103 : Oxford Nanopore Technologies plc.: Product Portfolio
Table 104 : Oxford Nanopore Technologies plc.: News/Key Developments, 2022-2024
Table 105 : QIAGEN: Company Snapshot
Table 106 : QIAGEN: Financial Performance, FY 2022 and 2023
Table 107 : QIAGEN: Product Portfolio
Table 108 : QIAGEN: News/Key Developments, 2022-2024
Table 109 : Revvity: Company Snapshot
Table 110 : Revvity: Financial Performance, FY 2022 and 2023
Table 111 : Revvity: Product Portfolio
Table 112 : Revvity: News/Key Developments, 2023
Table 113 : Standard BioTools: Company Snapshot
Table 114 : Standard BioTools: Financial Performance, FY 2022 and 2023
Table 115 : Standard BioTools: Product Portfolio
Table 116 : Standard BioTools: News/Key Developments, 2022-2024
Table 117 : Thermo Fisher Scientific Inc.: Company Snapshot
Table 118 : Thermo Fisher Scientific Inc.: Financial Performance, FY 2022 and 2023
Table 119 : Thermo Fisher Scientific Inc.: Product Portfolio
Table 120 : Thermo Fisher Scientific Inc.: News/Key Developments, 2022-2024
List of Figures
Summary Figure A : Global Market for RNA Sequencing, by Product, 2021-2029
Summary Figure B : Global Market for RNA Sequencing, by Technology, 2021-2029
Figure 1 : RNA-Seq Experiments for Transcriptomics
Figure 2 : RNA-Seq Experimental Workflow
Figure 3 : RNA-Seq Workflow Considerations
Figure 4 : Factors Related to Selecting the Right Platform for RNA-Seq
Figure 5 : Growth Strategy Recommendations: RNA Sequencing Market
Figure 6 : Market Dynamics
Figure 7 : Average Cost Per Genome: Y-o-Y Trend, 2011-2022
Figure 8 : Global Market Shares of RNA Sequencing, by Product, 2024
Figure 9 : Global Market for RNA Sequencing for Instruments, by Region, 2021-2029
Figure 10 : Global Market for RNA Sequencing for Tools and Reagents, by Region, 2021-2029
Figure 11 : Global Market for RNA Sequencing Sample Preparation for Tools & Reagents, by Region, 2021-2029
Figure 12 : Global Market for RNA Sequencing Library Preparation for Tools and Reagents, by Region, 2021-2029
Figure 13 : Global Market for RNA Sequencing for Software and Services, by Region, 2021-2029
Figure 14 : Global Market Shares of RNA Sequencing, by Technology, 2024
Figure 15 : Global Market for RNA Sequencing for Sequencing by Synthesis, by Region, 2021-2029
Figure 16 : Global Market for RNA Sequencing for Ion Torrent Semiconductor, by Region, 2021-2029
Figure 17 : Global Market for RNA Sequencing for Single-Molecule Real-Time Sequencing, by Region, 2021-2029
Figure 18 : Global Market for RNA Sequencing for Nanopore Sequencing, by Region, 2021-2029
Figure 19 : Major Applications of RNA Sequencing
Figure 20 : Global Market Shares of RNA Sequencing, by Application, 2024
Figure 21 : Global Market for RNA Sequencing for Expression Profiling Analysis, by Region, 2021-2029
Figure 22 : Global Market for RNA Sequencing for Small RNA Sequencing, by Region, 2021-2029
Figure 23 : Global Market for RNA Sequencing for De Novo Transcriptome Assembly, by Region, 2021-2029
Figure 24 : Global Market for RNA Sequencing for Variant Calling & Transcriptome Epigenetics, by Region, 2021-2029
Figure 25 : Global Market Shares of RNA Sequencing, by End User, 2024
Figure 26 : Global Market for RNA Sequencing for Academic Research Organizations, by Region, 2021-2029
Figure 27 : Role of RNA Sequencing in Drug Development
Figure 28 : Global Market for RNA Sequencing for Pharmaceutical and Biotechnology Companies, by Region, 2021-2029
Figure 29 : Global Market for RNA Sequencing for Clinical and Hospital Laboratories, by Region, 2021-2029
Figure 30 : Global Market for RNA Sequencing for Other End Users, by Region, 2021-2029
Figure 31 : Global Market Shares of RNA Sequencing, by Region, 2024
Figure 32 : North American Market for RNA Sequencing, by Product, 2021-2029
Figure 33 : North American Market for RNA Sequencing for Tools & Reagents, by Type, 2021-2029
Figure 34 : North American Market for RNA Sequencing, by Technology, 2021-2029
Figure 35 : North American Market for RNA Sequencing, by Application, 2021-2029
Figure 36 : North American Market for RNA Sequencing, by End User, 2021-2029
Figure 37 : European Market for RNA Sequencing, by Product, 2021-2029
Figure 38 : European Market for RNA Sequencing for Tools and Reagents, by Type, 2021-2029
Figure 39 : European Market for RNA Sequencing, by Technology, 2021-2029
Figure 40 : European Market for RNA Sequencing, by Application, 2021-2029
Figure 41 : European Market for RNA Sequencing, by End User, 2021-2029
Figure 42 : Growth Drivers in Asia-Pacific RNA Sequencing Market
Figure 43 : Asia-Pacific Market for RNA Sequencing, by Product, 2021-2029
Figure 44 : Asia-Pacific Market for RNA Sequencing for Tools and Reagents, by Type, 2021-2029
Figure 45 : Asia-Pacific Market for RNA Sequencing, by Technology, 2021-2029
Figure 46 : Asia-Pacific Market for RNA Sequencing, by Application, 2021-2029
Figure 47 : Asia-Pacific Market for RNA Sequencing, by End User, 2021-2029
Figure 48 : RoW Market for RNA Sequencing, by Product, 2021-2029
Figure 49 : RoW Market for RNA Sequencing for Tools & Reagents, by Type, 2021-2029
Figure 50 : RoW Market for RNA Sequencing, by Technology, 2021-2029
Figure 51 : RoW Market for RNA Sequencing, by Application, 2021-2029
Figure 52 : RoW Market for RNA Sequencing, by End User, 2021-2029
Figure 53 : Global Market Shares of RNA Sequencing, by Key Strategies Adopted, 2020-2024
Figure 54 : How a Strong ESG Proposition Benefits Businesses
Figure 55 : Percentage of Biotech Companies Providing ESG Disclosure, 2022
Figure 56 : Location of ESG Disclosure, 2022
Figure 57 : 10x Genomics: Revenue Shares, by Country/Region, FY 2023
Figure 58 : Agilent Technologies Inc.: Revenue Shares, by Business Unit, FY 2023
Figure 59 : Agilent Technologies Inc.: Revenue Shares, by Country/Region, FY 2023
Figure 60 : Bio-Rad Laboratories Inc.: Revenue Shares, by Business Unit, FY 2023
Figure 61 : Bio-Rad Laboratories Inc.: Revenue Shares, by Country/Region, FY 2023
Figure 62 : F. Hoffman-La Roche Ltd.: Revenue Shares, by Business Unit, FY 2023
Figure 63 : F. Hoffman-La Roche Ltd.: Revenue Shares, by Country/Region, FY 2023
Figure 64 : Illumina Inc.: Revenue Shares, by Business Unit, FY 2023
Figure 65 : Illumina Inc.: Revenue Shares, by Country/Region, FY 2023
Figure 66 : Oxford Nanopore Technologies plc.: Revenue Shares, by Business Unit, FY 2023
Figure 67 : Oxford Nanopore Technologies plc.: Revenue Shares, by Country/Region, FY 2023
Figure 68 : QIAGEN: Revenue Shares, by Business Unit, FY 2023
Figure 69 : QIAGEN: Revenue Shares, by Country/Region, FY 2023
Figure 70 : Revvity: Revenue Shares, by Business Unit, FY 2023
Figure 71 : Revvity: Revenue Shares, by Country/Region, FY 2023
Figure 72 : Standard BioTools: Revenue Shares, by Business Unit, FY 2023
Figure 73 : Standard BioTools: Revenue Shares, by Country/Region, FY 2023
Figure 74 : Thermo Fisher Scientific Inc.: Revenue Shares, by Business Unit, FY 2023
Figure 75 : Thermo Fisher Scientific Inc.: Revenue Shares, by Country/Region, FY 2023
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