Please Wait.....
Report
Protein Expression: Global Markets
Market Research Report I 2025-11-25 I 157 Pages I BCC Research
Description
Report Scope
The report provides an overview of the global protein expression market and analyzes key market trends. Global revenue ($ million) for the base year 2024 and estimated data for the forecast period, 2025 through 2030, are also included. The market is segmented into expression system, product types, application, end user and regions. The regions covered in this study are North America, Europe, Asia-Pacific (APAC) and the Rest of the World (RoW), with a focus on major countries in these regions.
The report examines trends and challenges that affect the market and vendor landscape; analyzes environmental, social and corporate governance (ESG) developments; and discusses emerging technologies related to the market.
The report concludes with an analysis of the competitive landscape, providing rankings and market shares of key companies in the global protein expression market. A dedicated section of company profiles provides an overview, key financials, product portfolios and recent developments of leading companies, including a patent analysis.
Report Includes
- 52 data tables and 65 additional tables
- An overview of the global market for protein expression
- In-depth analysis of global market trends, featuring historical revenue data for 2022-2024, estimated figures for 2025, as well as forecasts for 2030. This analysis includes projections of compound annual growth rates (CAGRs) through 2030
- Evaluation of the current market size and revenue growth prospects specific to the protein expression, accompanied by a market share analysis by system type, product, application, end user and region
- Analysis of current and future demand in the global protein expression, along with a detailed analysis of the competitive environment, market regulations and reimbursement practices
- Analysis of drivers, challenges and opportunities affecting market growth
- Coverage of evolving technologies, the current and future market potential, R&D activities, growth strategies, new product pipeline, regulatory framework and reimbursement scenarios, and ESG trends of the market
- Market share analysis of the key market participants in the protein expression industry, along with their research priorities, product portfolios, global rankings and competitive landscape
- Profiles of the major companies, including Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Merck KGaA, Sartorius AG and Agilent Technologies Inc.
Executive Summary
Summary:
The global market for protein expression is estimated to grow from $4.7 billion in 2025 to reach $7.9 billion by 2030, at a compound annual growth rate (CAGR) of 10.9% from 2025 through 2030.
Protein expression is a technique involving three processes - translation, transcription and posttranslational modification - that play vital roles in various applications, including biologics production, therapeutic protein production and research applications. The biotechnology business utilizes prokaryotic (bacterial) and eukaryotic (animal, fungal, or plant) cells to synthesize recombinant proteins - the protein to be expressed determines the cell choice. Although bacteria can yield a high volume of recombinant protein, quality remains a challenge because, in some cases, the expressed proteins do not fold properly. It can also be challenging to conduct post-translational modifications in bacterial cells, a characteristic that is often found in some eukaryotic proteins.
The protein expression market is rapidly expanding due to investments in biotechnology research and the need for therapeutic proteins to treat chronic illnesses.
Table of Contents
Chapter 1 Executive Summary
Market Outlook
Scope of Report
Market Summary
Market Growth Factors
Emerging Technologies
Segmental Analysis
Regional Analysis
Conclusion
Chapter 2 Market Overview
Technology Background
Protein Expression Workflow
Choice of Cell Type
Choice of Plasmid
Choice of Cell Expression System
Introduction to Protein Expression Systems
Protein Synthesis Machinery
Cloning Technologies
Constitutive and Inducible Promoters Commonly Used in Recombinant Protein Expression Systems
Production of Recombinant Proteins
Recombinant Protein Expression Methods
Comparison of Expression Systems
Post-Translational Processing
Problems Associated with the Production of Protein
Loss of Expression
Macroeconomic Factors Analysis
PESTEL Analysis
Impact of U.S. Tariff Laws on the Protein Expression Market
Porter's Five Forces Analysis
Bargaining Power of Buyers: Moderate
Bargaining Power of Suppliers: Moderate
Threat of Substitute Products: Low
Threat of New Entrants: Moderate
Industry Competition: High
Chapter 3 Market Dynamics
Overview
Market Drivers
Demand for Therapeutic Proteins and Biologics
Investments in Biopharmaceuticals
Technological Advances in Protein Expression Systems
Market Restraints
Complex Government Regulations and Policies
High Cost of Protein Drugs
Market Opportunities
Demand for Biopharmaceuticals in Emerging Countries
Expanded Applications for CRISPR Technology
Chapter 4 Regulatory Landscape
Overview
The U.S.
Europe
Asia-Pacific
Rest of the World
Chapter 5 Emerging Technologies and New Developments
Overview
CRISPR/Cas9 Genome Editing
Synthetic Biology
AI Integration in Protein Expression
Chapter 6 Market Segmentation Analysis
Segmentation Breakdown
Market Breakdown by System Type
Key Takeaways
Prokaryotic Expression Systems
Mammalian Cell Expression Systems
Yeast Expression Systems
Insect Cell Expression Systems
Cell-Free Expression Systems
Algal-based Expression Systems
Market Breakdown by Product Type
Key Takeaways
Reagents
Expression Vectors
Competent Cells
Instruments
Services
Market Breakdown by Application
Key Takeaways
Therapeutics
Industrial
Research
Market Breakdown by End User
Key Takeaways
Pharmaceutical and Biotechnology Companies
Contract Research Organizations
Academic Research Institutes
Others
Geographic Breakdown
Market Breakdown by Region
Key Takeaways
North America
Europe
Asia-Pacific
Rest of the World
Chapter 7 Competitive Intelligence
Key Takeaways
Top Companies' Ranking, 2024
Strategic Analysis
Chapter 8 Sustainability in the Protein Expression Market: ESG Perspective
Sustainability in the Protein Expression Market
Understanding ESG Data
ESG Performance Analysis
Environmental Performance
Social Performance
Governance Performance
Concluding Remarks from BCC
Chapter 9 Patent Landscape
Overview
Patents, by Year
Patents, by Leading Applicants
Patents, by Document Type
Recent Patents Relating to Protein Expression Technology
Chapter 10 Appendix
Methodology
References
Abbreviations
Company Profiles
AGILENT TECHNOLOGIES INC.
BIO-RAD LABORATORIES INC.
CORNING INC.
DANAHER CORP.
FUJIFILM CELLULAR DYNAMICS INC.
GENSCRIPT
LONZA
MERCK KGAA
NEW ENGLAND BIOLABS
ORIGENE TECHNOLOGIES INC.
PROMEGA CORP.
PROTEOGENIX INC.
QIAGEN
SARTORIUS AG
THERMO FISHER SCIENTIFIC INC.
List of Tables
Summary Table : Global Market for Protein Expression, by Region, Through 2030
Table 1 : Advantages and Disadvantages of Protein Expression Systems
Table 2 : Prokaryotes vs. Eukaryotes Protein Synthesis
Table 3 : Comparison of Expression Systems
Table 4 : Asia-Pacific Regulatory Landscape
Table 5 : RoW Regulatory Landscape
Table 6 : Comparison of Protein Expression Systems and Their Respective Advantages and Disadvantages
Table 7 : Advantages, Challenges and Most Common Applications of Protein Expression Systems
Table 8 : Global Market for Protein Expression, by Type, Through 2030
Table 9 : Global Market for Prokaryotic Expression Systems, by Region, Through 2030
Table 10 : Global Market for Mammalian Cell Expression Systems, by Region, Through 2030
Table 11 : Global Market for Yeast Expression Systems, by Region, Through 2030
Table 12 : Global Market for Insect Cell Expression Systems, by Region, Through 2030
Table 13 : Global Market for Cell-Free Protein Expression Systems, by Region, Through 2030
Table 14 : Global Market for Algal-based Expression Systems, by Region, Through 2030
Table 15 : Global Market for Protein Expression, by Product, Through 2030
Table 16 : Global Protein Expression Market for Reagents, by Region, Through 2030
Table 17 : Characteristics of Commonly Used Expression Hosts
Table 18 : Global Protein Expression Market for Expression Vectors, by Region, Through 2030
Table 19 : Global Protein Expression Market for Competent Cells, by Region, Through 2030
Table 20 : Global Protein Expression Market for Instruments, by Region, Through 2030
Table 21 : Select Protein Expression Services
Table 22 : Global Protein Expression Market for Services, by Region, Through 2030
Table 23 : Global Market for Protein Expression, by Application, Through 2030
Table 24 : Global Protein Expression Market for Therapeutics, by Region, Through 2030
Table 25 : Global Protein Expression Market for Industrial Use, by Region, Through 2030
Table 26 : Global Protein Expression Market for Research Use, by Region, Through 2030
Table 27 : Global Market for Protein Expression, by End User, Through 2030
Table 28 : Global Protein Expression Market for Pharmaceutical and Biotechnology Companies, by Region, Through 2030
Table 29 : Global Protein Expression Market for Contract Research Organizations, by Region, Through 2030
Table 30 : Global Protein Expression Market for Academic Research Organizations, by Region, Through 2030
Table 31 : Global Protein Expression Market for Other End Users, by Region, Through 2030
Table 32 : Global Market for Protein Expression, by Region, Through 2030
Table 33 : North American Market for Protein Expression, by Type, Through 2030
Table 34 : North American Market for Protein Expression, by Product, Through 2030
Table 35 : North American Market for Protein Expression, by Application, Through 2030
Table 36 : North American Market for Protein Expression, by End User, Through 2030
Table 37 : North American Market for Protein Expression, by Country, Through 2030
Table 38 : European-based Companies' R&D Expenditures and Comparison of Their Net Sales, 2023
Table 39 : European Market for Protein Expression, by Type, Through 2030
Table 40 : European Market for Protein Expression, by Product, Through 2030
Table 41 : European Market for Protein Expression, by Application, Through 2030
Table 42 : European Market for Protein Expression, by End User, Through 2030
Table 43 : European Market for Protein Expression, by Country, Through 2030
Table 44 : Asia-Pacific Market for Protein Expression, by Type, Through 2030
Table 45 : Asia-Pacific Market for Protein Expression, by Product, Through 2030
Table 46 : Asia-Pacific Market for Protein Expression, by Application, Through 2030
Table 47 : Asia-Pacific Market for Protein Expression, by End User, Through 2030
Table 48 : Asia-Pacific Market for Protein Expression, by Country, Through 2030
Table 49 : RoW Market for Protein Expression, by Type, Through 2030
Table 50 : RoW Market for Protein Expression, by Product, Through 2030
Table 51 : RoW Market for Protein Expression, by Application, Through 2030
Table 52 : RoW Market for Protein Expression, by End User, Through 2030
Table 53 : RoW Market for Protein Expression, by Subregion, Through 2030
Table 54 : Top Companies' Ranking, 2024
Table 55 : Recent Developments in the Protein Expression Market, 2023-2025
Table 56 : Key Focus Areas in ESG Metrics
Table 57 : ESG Rankings for Major Protein Expression Companies, 2025*
Table 58 : ESG: Environmental Overview
Table 59 : ESG: Social Overview
Table 60 : ESG: Governance Overview
Table 61 : Patent Applications Related to Protein Expression, by Applicant, 2020-2025
Table 62 : Protein Expression Technology Patents Filed, 2024
Table 63 : Protein Expression Technology Patents Filed, 2025
Table 64 : Abbreviations Used in the Protein Expression Market Report
Table 65 : Agilent Technologies Inc.: Company Snapshot
Table 66 : Agilent Technologies Inc.: Financial Performance, FY 2023 and 2024
Table 67 : Agilent Technologies Inc.: Product Portfolio
Table 68 : Agilent Technologies Inc.: News/Key Developments, 2024
Table 69 : Bio-Rad Laboratories Inc.: Company Snapshot
Table 70 : Bio-Rad Laboratories Inc.: Financial Performance, FY 2023 and 2024
Table 71 : Bio-Rad Laboratories Inc.: Product Portfolio
Table 72 : Bio-Rad Laboratories Inc.: News/Key Developments, 2025
Table 73 : Corning Inc.: Company Snapshot
Table 74 : Corning Inc.: Financial Performance, FY 2023 and 2024
Table 75 : Corning Inc.: Product Portfolio
Table 76 : Danaher Corp.: Company Snapshot
Table 77 : Danaher Corp.: Financial Performance, FY 2023 and 2024
Table 78 : Danaher Corp.: Product Portfolio
Table 79 : Danaher Corp.: News/Key Developments, 2023-2025
Table 80 : FUJIFILM Cellular Dynamics Inc.: Company Snapshot
Table 81 : FUJIFILM Cellular Dynamics Inc.: Product Portfolio
Table 82 : GenScript: Company Snapshot
Table 83 : GenScript: Financial Performance, FY 2023 and 2024
Table 84 : GenScript: Product Portfolio
Table 85 : GenScript: News/Key Developments, 2024-2025
Table 86 : Lonza: Company Snapshot
Table 87 : Lonza: Financial Performance, FY 2023 and 2024
Table 88 : Lonza: Product Portfolio
Table 89 : Lonza: News/Key Developments, 2023-2025
Table 90 : Merck KGaA: Company Snapshot
Table 91 : Merck KGaA: Financial Performance, FY 2023 and 2024
Table 92 : Merck KGaA: Product Portfolio
Table 93 : Merck KGaA: News/Key Developments, 2023-2024
Table 94 : New England Biolabs: Company Snapshot
Table 95 : New England Biolabs: Product Portfolio
Table 96 : New England Biolabs: News/Key Developments, 2025
Table 97 : OriGene Technologies Inc.: Company Snapshot
Table 98 : OriGene Technologies Inc.: Product Portfolio
Table 99 : OriGene Technologies Inc.: News/Key Developments, 2025
Table 100 : Promega Corp.: Company Snapshot
Table 101 : Promega Corp.: Product Portfolio
Table 102 : Promega Corp.: News/Key Developments, 2025
Table 103 : ProteoGenix Inc.: Company Snapshot
Table 104 : ProteoGenix Inc.: Product Portfolio
Table 105 : Qiagen: Company Snapshot
Table 106 : Qiagen: Financial Performance, FY 2023 and 2024
Table 107 : Qiagen: Product Portfolio
Table 108 : Qiagen: News/Key Developments, 2023
Table 109 : Sartorius AG: Company Snapshot
Table 110 : Sartorius AG: Financial Performance, FY 2023 and 2024
Table 111 : Sartorius AG: Product Portfolio
Table 112 : Sartorius AG: News/Key Developments, 2023-2025
Table 113 : Thermo Fisher Scientific Inc.: Company Snapshot
Table 114 : Thermo Fisher Scientific Inc.: Financial Performance, FY 2023 and 2024
Table 115 : Thermo Fisher Scientific Inc.: Product Portfolio
Table 116 : Thermo Fisher Scientific Inc.: News/Key Developments, 2025
List of Figures
Summary Figure : Global Market Shares of Protein Expression, by Region, 2024
Figure 1 : Protein Expression Workflow
Figure 2 : PESTEL Analysis: Protein Expression Market
Figure 3 : Porter's Five Forces Analysis: Protein Expression Market
Figure 4 : Market Dynamics of Protein Expression
Figure 5 : Venture Capital Averages for Biopharma Therapeutics and Platform Companies, 2010-2024
Figure 6 : Technological Advances in Protein Expression Systems
Figure 7 : Emerging Technologies in the Protein Expression Market
Figure 8 : Global Market Shares of Protein Expression, by Type, 2024
Figure 9 : Global Market Shares of Protein Expression, by Product, 2024
Figure 10 : Global Market Shares of Protein Expression, by Application, 2024
Figure 11 : Global Market Shares of Protein Expression, by End User, 2024
Figure 12 : Global Market Shares of Protein Expression, by Region, 2024
Figure 13 : North American Market Shares of Protein Expression, by Country, 2024
Figure 14 : U.S. Elderly Population (65 and Older), Projection and Trends, 2010-2050
Figure 15 : European Market Shares of Protein Expression, by Country, 2024
Figure 16 : Asia-Pacific Market Shares of Protein Expression, by Country, 2024
Figure 17 : RoW Market Shares of Protein Expression, by Subregion, 2024
Figure 18 : How a Strong ESG Proposition Benefits Businesses
Figure 19 : Patents Granted Related to Protein Expression Technology, by Year, 2020-2025
Figure 20 : Patent Shares for Protein Expression Technology, by Document Type, 2020-2025
Figure 21 : Agilent Technologies Inc.: Revenue Share, by Business Unit, FY 2024
Figure 22 : Agilent Technologies Inc.: Revenue Share, by Country/Region, FY 2024
Figure 23 : Bio-Rad Laboratories Inc.: Revenue Share, by Business Unit, FY 2024
Figure 24 : Bio-Rad Laboratories Inc.: Revenue Share, by Country/Region, FY 2024
Figure 25 : Corning Inc.: Revenue Share, by Business Unit, FY 2024
Figure 26 : Corning Inc.: Revenue Share, by Country/Region, FY 2024
Figure 27 : Danaher Corp.: Revenue Share, by Business Unit, FY 2024
Figure 28 : Danaher Corp.: Revenue Share, by Country/Region, FY 2024
Figure 29 : GenScript: Revenue Share, by Business Unit, FY 2024
Figure 30 : GenScript: Revenue Share, by Country/Region, FY 2024
Figure 31 : Lonza: Revenue Share, by Business Unit, FY 2024
Figure 32 : Lonza: Revenue Share, by Country/Region, FY 2024
Figure 33 : Merck KGaA: Revenue Share, by Business Unit, FY 2024
Figure 34 : Merck KGaA: Revenue Share, by Country/Region, FY 2024
Figure 35 : Qiagen: Revenue Share, by Business Unit, FY 2024
Figure 36 : Qiagen: Revenue Share, by Country/Region, FY 2024
Figure 37 : Sartorius AG: Revenue Share, by Business Unit, 2024
Figure 38 : Sartorius AG: Revenue Share, by Country/Region, 2024
Figure 39 : Thermo Fisher Scientific Inc.: Revenue Share, by Business Unit, FY 2024
Figure 40 : Thermo Fisher Scientific Inc.: Revenue Share, by Country/Region, FY 2024
- Not Sure / Need Reassuring
- Confirm Content
-
Content is provided by our partners and every effort is made to make Market Report details as clear as possible. If you are not sure the exact content you require is included in this study you can Contact us to double check. To do this you can:
Use the ‘? ASK A QUESTION’ below the license / prices and to the right of this box. This will come directly to our team who will work on dealing with your request as soon as possible.
Write to directly on support@scotts-international.com with details. Please include as much information as possible including the name of report or link so our staff will be able to work on you request.
Telephone us directly on 0048 603 394 346 and an experienced member of team will be on hand to answer.
-
- Sample Pages
-
With the vast majority of our partners we can obtain Sample Pages to support your decision. This is something we can arrange without revealing your personal details.
It is important to note that we will not be able to provide you the exact data or statistics such as Market Size and Forecasts. Sample pages usually confirm the layout or the Categories included in Charts and Graphs, excluding specific data.
To ask for Sample Pages by contact us through ‘? ASK A QUESTION’, support@scotts-international.com, or by telephoning 0048 603 394 346.
-
- Check for Alternatives
-
Whilst we try to make our online platform as easy to use as possible there is always the possibility that a better alternative has not been found in your search.
To avoid this possibility Contact us through ‘? ASK A QUESTION’, support@scotts-international.com, or by telephoning 0048 603 394 346 and a Senior Team Member can review your requirements and send a list of possibilities with opinions and recommendations.
-
- Confirm Content
- Prices / Formats / Delivery
- Prices
-
All prices are set by our partners and should be exactly the same as those listed on their own websites. We work on a Revenue share basis ensuring that you never pay more than what is offered elsewhere.
Should you find the price cheaper on another platform we recommend you to Contact us as we should be able to match this price. You can Contact us though through ‘? ASK A QUESTION’, support@scotts-international.com, or by telephoning 0048 603 394 346.
-
- Discounts
-
As we work in close partnership with our Partners from time to time we can secure discounts and assist with negotiations, this is part of our personalised service to you.
Discounts can sometimes be arranged for speedily placed orders; multiple report purchases or Higher License purchases.
To check if a Discount is possible please Contact our experienced team through ‘? ASK A QUESTION’, support@scotts-international.com, or by telephoning 0048 603 394 346.
-
- Available Currencies
-
Most Market Reports on our platform are listed in USD or EURO based on the wishes of our Partners. To avoid currency fluctuations and potential price differentiations we do not offer the possibility to change the currency online.
Should you wish to pay in a different currency to that advertised online we do accept payments in USD, EURO, GBP and PLN. The price will be calculated based on the relevant exchange rate taken from our National Bank.
To pay in a different above currency to that advertised online please Contact our team and a quotation will be sent within a couple of hours with payment details.
-
- Licenses
-
License options vary from Partner to Partner as is usually based on the number of Users that will benefitting from the report. It is very important that License ordered is not breached as this could have potential negative consequences for you individually or your employer.
If you have questions or need confirmation about the specific license we recommend you to Contact us and a detailed explanation will be provided.
-
- Global Site License
-
The Global Site License is the most comprehensive license available. By selecting this license, the Market Report can be shared with other ‘Allowed Users’ and any other member of staff from the same organisation regardless of geographic location.
It is important to note that this may exclude Parent Companies or Subsidiaries.
If you have questions or need confirmation about the specific license we recommend you to Contact us and a detailed explanation will be provided.
-
- Formats
-
The most common format is PDF, however in certain circumstances data may be present in Excel format or Online, especially in the case of Database or Directories. In addition, for certain higher license options a CD may also be provided.
If you have questions or need clarification about the specific formats we recommend you to Contact us and a detailed explanation will be provided.
-
- Delivery
-
Delivery is fulfilled by our partners directly. Once an order has been placed we inform the partner by sharing the delivery email details given in the order process.
Delivery is usually made within 24 hours of an order being placed, however it may take longer should your order be placed prior to the weekend or if otherwise specified on the Market Report details page. Additionally, if details have been not fully completed in the Order process a delay in delivery is possible.
If a delay in delivery is expected you will be informed about it immediately.
-
- Shipping Charges
-
As most Market Reports are delivered in PDF format we almost never have to add additional Shipping Charges. If, however you are ordering a Higher License service or a specific delivery format (e.g. CD version) charges may apply.
If you are concerned about additional Shipping Charges we recommend you to Contact us to double check.
-
- Prices
- Ordering
- By Credit Card
-
We work in Partnership with PayU to ensure payments are made securely in a fast and effortless way. PayU is the e-payments division of Naspers.
Naspers operates in over 133 International Markets and ranks 3rd Globally in terms of the number of e-commerce customers served.
For more information on PayU please visit: https://www.payu.pl/en/about-us
-
- By Money Transfer
-
If you require an invoice prior to payment, this is possible. To ensure a speedy delivery of the Market Report we require all relevant company details and you agree to maximum payment terms of 30 days from receipt of order.
With our regular clients deliver of the Market Report can be made prior to receiving payment, however in some circumstances we may ask for payment to be received before arranging for the Market Report to be delivered.
-
- By Credit Card
- Security
- Website security
-
We have specifically partnered with leading International companies to protect your privacy by using different technologies and processes to ensure security.
Everything submitted to Scotts International is encrypted via SSL (Secure Socket Layer) and all personal information provided to Scotts International is stored on computer systems with limited access in controlled environments.
-
- Credit Card Security
-
We partner with PayU (https://www.payu.pl/en/about-us) to ensure all credit card payments are made securely in a fast and effortless way.
PayU offers 250+ various payment channels and eWallet services across 4 continents allowing buyers to pay electronically, whether on a computer or a mobile device.
-
- Website security