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Report
North America Cancer Immunotherapy Market - Industry Trends and Forecast to 2035
Market Report I 2023-12-01 I 251 Pages I Data Bridge Market Research
The North America cancer immunotherapy market is expected to reach USD 147,824.58 million by 2031 from USD 52,159.29 million in 2023, growing at a CAGR of 14.9% during the forecast period of 2024 to 2031.
Market Segmentation
North America Cancer Immunotherapy Market, By Product Type (Checkpoint Inhibitors, Monoclonal Antibodies, Vaccines, Cell Therapies, Immunomodulators, and Oncolytic Virus), Application (Lung Cancer, Breast Cancer, Melanoma, Myeloma, Prostate Cancer, Ovarian Cancer, Cervical Cancer, Stomach Cancer, Colorectal Cancer, Head & Neck Cancer, and Others), End User (Hospitals, Oncology Clinics, Homecare, and Others), Form (Intravenous (IV), Intramuscular, and Oral), Distribution Channel (Direct Tenders, Retail Sales, and Pharmacies), Country (U.S., Canada, and Mexico) - Industry Trends and Forecast to 2031
Overview of North America Cancer Immunotherapy Market Dynamics
Driver
- Rising prevalence of cancer incidences
Restraint
- Increasing occurrence of immune-related adverse events
Opportunity
- Growing trend towards combination therapies
Market Players
Some of the major market players operating in the North America cancer immunotherapy market are:
- Merck & Co., Inc.
- F. Hoffmann-La Roche Ltd
- Bristol-Myers Squibb Company
- Janssen Pharmaceutical
- AstraZeneca
- Gilead Sciences, Inc.
- Eli Lilly and Company
- Amgen Inc.
- Novartis AG
- GSK
- Pfizer Inc.
- Incyte
TABLE OF CONTENTS
1 INTRODUCTION 83
1.1 OBJECTIVES OF THE STUDY 83
1.2 MARKET DEFINITION 83
1.3 OVERVIEW OF THE NORTH AMERICA CANCER IMMUNOTHERAPY MARKET 83
1.4 CURRENCY AND PRICING 85
1.5 LIMITATIONS 85
1.6 MARKETS COVERED 85
2 MARKET SEGMENTATION 89
2.1 MARKETS COVERED 89
2.2 GEOGRAPHICAL SCOPE 90
2.3 YEARS CONSIDERED FOR THE STUDY 91
2.4 DBMR TRIPOD DATA VALIDATION MODEL 92
2.5 PRIMARY INTERVIEWS WITH KEY OPINION LEADERS 95
2.6 MULTIVARIATE MODELLING 96
2.7 PRODUCT TYPE SEGMENT LIFELINE CURVE 96
2.8 MARKET END USER COVERAGE GRID 97
2.9 DBMR MARKET POSITION GRID 98
2.10 VENDOR SHARE ANALYSIS 99
2.11 SECONDARY SOURCES 100
2.12 ASSUMPTIONS 100
3 EXECUTIVE SUMMARY 101
4 PREMIUM INSIGHTS 103
4.1 PESTAL ANALYSIS 104
4.2 PORTERS 5 FORCES 105
5 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET: REGULATIONS 106
6 MARKET OVERVIEW 114
6.1 DRIVERS 116
6.1.1 RISING PREVALENCE OF CANCER INCIDENCES 116
6.1.2 RISING TECHNOLOGICAL ADVANCEMENTS 116
6.1.3 INCREASED UNDERSTANDING OF TUMOR MICROENVIRONMENT 117
6.1.4 RISE IN PATIENT AWARENESS AND DEMAND FOR TARGETED TREATMENT 117
6.2 RESTRAINTS 118
6.2.1 INCREASING OCCURRENCE OF IMMUNE-RELATED ADVERSE EVENTS 118
6.2.2 DEVELOPING RESISTANCE TO CANCER TREATMENT 118
6.3 OPPORTUNITIES 119
6.3.1 GROWING TREND TOWARDS COMBINATION THERAPIES 119
6.3.2 RISING INTEGRATION OF ARTIFICIAL INTELLIGENCE AND DIGITAL HEALTH TOOLS 119
6.3.3 DEVELOPMENT OF NEXT-GENERATION IMMUNOTHERAPIES 120
6.4 CHALLENGES 121
6.4.1 LACK OF STANDARDIZATION IN BIOMARKER TESTING 121
6.4.2 COMPLEXITY OF DEVELOPING AND IMPLEMENTING PERSONALIZED MEDICINE 121
7 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY PRODUCT TYPE 122
7.1 OVERVIEW 123
7.2 CHECKPOINT INHIBITORS 126
7.2.1 PROGRAMMED DEATH 1 (PD-1) & PROGRAMMED DEATH LIGAND 1 (PD-L1) 127
7.2.2 CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN-4 (CTLA-4) 127
7.3 MONOCLONAL ANTIBODIES 128
7.3.1 NAKED MONOCLONAL ANTIBODIES 129
7.3.2 CONJUGATED MONOCLONAL ANTIBODIES 129
7.3.3 BISPECIFIC MONOCLONAL ANTIBODIES 129
7.4 VACCINES 130
7.4.1 PROPHYLACTIC VACCINES 131
7.4.2 THERAPEUTIC VACCINES 131
7.5 CELL THERAPIES 131
7.5.1 CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL THERAPY 132
7.5.2 T CELL THERAPY 132
7.6 IMMUNOMODULATORS 132
7.6.1 INTERFERONS 133
7.6.2 INTERLEUKINS 133
7.6.3 GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR 133
7.7 ONCOLYTIC VIRUS 134
8 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY END USER 135
8.1 OVERVIEW 136
8.2 HOSPITALS 139
8.3 ONCOLOGY CLINICS 140
8.4 HOMECARE 140
8.5 OTHERS 141
9 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY DISTRIBUTION CHANNEL 142
9.1 OVERVIEW 143
9.2 DIRECT TENDERS 146
9.3 RETAIL SALES 147
9.4 PHARMACIES 147
9.4.1 HOSPITAL 148
9.4.2 RETAIL 148
9.4.3 ONLINE 148
10 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY FORM 149
10.1 OVERVIEW 150
10.2 INTRAVENOUS (IV) 153
10.3 INTRAMUSCULAR 154
10.4 ORAL 154
11 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY APPLICATION 155
11.1 OVERVIEW 156
11.2 LUNG CANCER 159
11.2.1 CHECKPOINT INHIBITORS 160
11.2.2 MONOCLONAL ANTIBODIES 160
11.2.3 CELL THERAPIES 160
11.2.4 IMMUNOMODULATORS 160
11.3 BREAST CANCER 161
11.3.1 CHECKPOINT INHIBITORS 161
11.3.2 MONOCLONAL ANTIBODIES 161
11.3.3 CELL THERAPIES 162
11.3.4 IMMUNOMODULATORS 162
11.4 MELANOMA 162
11.4.1 CHECKPOINT INHIBITORS 163
11.4.2 MONOCLONAL ANTIBODIES 163
11.4.3 CELL THERAPIES 163
11.4.4 IMMUNOMODULATORS 163
11.4.5 ONCOLYTIC VIRUS 163
11.5 MULTIPLE MYELOMA 164
11.5.1 CHECKPOINT INHIBITORS 164
11.5.2 MONOCLONAL ANTIBODIES 164
11.5.3 CELL THERAPIES 164
11.5.4 IMMUNOMODULATORS 165
11.6 PROSTATE CANCER 165
11.6.1 CHECKPOINT INHIBITORS 165
11.6.2 MONOCLONAL ANTIBODIES 166
11.6.3 CELL THERAPIES 166
11.6.4 IMMUNOMODULATORS 166
11.6.5 VACCINES 166
11.7 OVARIAN CANCER 166
11.7.1 CHECKPOINT INHIBITORS 167
11.7.2 MONOCLONAL ANTIBODIES 167
11.7.3 CELL THERAPIES 167
11.7.4 IMMUNOMODULATORS 167
11.8 CERVICAL CANCER 168
11.8.1 CHECKPOINT INHIBITORS 168
11.8.2 MONOCLONAL ANTIBODIES 168
11.8.3 VACCINES 169
11.8.4 CELL THERAPIES 169
11.8.5 IMMUNOMODULATORS 169
11.9 STOMACH CANCER 169
11.9.1 CHECKPOINT INHIBITORS 170
11.9.2 MONOCLONAL ANTIBODIES 170
11.9.3 CELL THERAPIES 170
11.9.4 IMMUNOMODULATORS 170
11.10 COLORECTAL CANCER 170
11.10.1 CHECKPOINT INHIBITORS 171
11.10.2 MONOCLONAL ANTIBODIES 171
11.10.3 CELL THERAPIES 171
11.10.4 IMMUNOMODULATORS 171
11.11 HEAD AND NECK CANCER 172
11.11.1 CHECKPOINT INHIBITORS 172
11.11.2 MONOCLONAL ANTIBODIES 172
11.11.3 CELL THERAPIES 172
11.11.4 IMMUNOMODULATORS 173
11.12 OTHERS 173
11.12.1 CHECKPOINT INHIBITORS 173
11.12.2 MONOCLONAL ANTIBODIES 173
11.12.3 VACCINES 174
11.12.4 CELL THERAPIES 174
11.12.5 IMMUNOMODULATORS 174
12 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY REGION 175
12.1 NORTH AMERICA 177
12.1.1 U.S. 185
12.1.2 CANADA 193
12.1.3 MEXICO 201
13 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, COMPANY LANDSCAPE 209
13.1 COMPANY SHARE ANALYSIS: NORTH AMERICA 209
14 SWOT ANALYSIS 210
15 COMPANY PROFILES 211
15.1 MERCK & CO., INC. 211
15.1.1 COMPANY SNAPSHOT 211
15.1.2 REVENUE ANALYSIS 211
15.1.3 COMPANY SHARE ANALYSIS 212
15.1.4 PRODUCT PORTFOLIO 212
15.1.5 RECENT DEVELOPMENTS 212
15.2 F. HOFFMANN-LA ROCHE LTD 213
15.2.1 COMPANY SNAPSHOT 213
15.2.2 REVENUE ANALYSIS 213
15.2.3 COMPANY SHARE ANALYSIS 214
15.2.4 PRODUCT PORTFOLIO 214
15.2.5 RECENT DEVELOPMENTS 214
15.3 BRISTOL-MYERS SQUIBB COMPANY 216
15.3.1 COMPANY SNAPSHOT 216
15.3.2 REVENUE ANALYSIS 216
15.3.3 COMPANY SHARE ANALYSIS 217
15.3.4 PRODUCT PORTFOLIO 217
15.3.5 RECENT DEVELOPMENTS 218
15.4 JANSSEN NORTH AMERICA SERVICES, LLC 219
15.4.1 COMPANY SNAPSHOT 219
15.4.2 REVENUE ANALYSIS 219
15.4.3 COMPANY SHARE ANALYSIS 220
15.4.4 PRODUCT PORTFOLIO 220
15.4.5 RECENT DEVELOPMENTS 221
15.5 ASTRAZENECA 222
15.5.1 COMPANY SNAPSHOT 222
15.5.2 REVENUE ANALYSIS 222
15.5.3 COMPANY SHARE ANALYSIS 223
15.5.4 PRODUCT PORTFOLIO 223
15.5.5 RECENT DEVELOPMENTS 224
15.6 ABBVIE INC. 225
15.6.1 COMPANY SNAPSHOT 225
15.6.2 PIPELINE PORTFOLIO 225
15.6.3 RECENT DEVELOPMENTS 225
15.7 AMGEN INC. 226
15.7.1 COMPANY SNAPSHOT 226
15.7.2 REVENUE ANALYSIS 227
15.7.3 PIPELINE PORTFOLIO 227
15.7.4 PRODUCT PORTFOLIO 228
15.7.5 RECENT DEVELOPMENTS 228
15.8 ATARA BIOTHERAPEUTICS, INC. 229
15.8.1 COMPANY SNAPSHOT 229
15.8.2 PIPELINE PORTFOLIO 229
15.8.3 RECENT DEVELOPMENTS 229
15.9 BAYER AG 230
15.9.1 COMPANY SNAPSHOT 230
15.9.2 PIPELINE PORTFOLIO 230
15.9.3 RECENT DEVELOPMENTS 230
15.10 CELLDEX THERAPEUTICS. 232
15.10.1 COMPANY SNAPSHOT 232
15.10.2 PIPELINE PORTFOLIO 232
15.10.3 RECENT DEVELOPMENTS 232
15.11 CELLECTIS 233
15.11.1 COMPANY SNAPSHOT 233
15.11.2 PIPELINE PORTFOLIO 233
15.11.3 RECENT DEVELOPMENTS 233
15.12 GILEAD SCIENCES, INC. 234
15.12.1 COMPANY SNAPSHOT 234
15.12.2 REVENUE ANALYSIS 234
15.12.3 PRODUCT PORTFOLIO 235
15.12.4 RECENT DEVELOPMENTS 235
15.13 GSK PLC. 236
15.13.1 COMPANY SNAPSHOT 236
15.13.2 REVENUE ANALYSIS 236
15.13.3 PRODUCT PORTFOLIO 237
15.13.4 RECENT DEVELOPMENTS 237
15.14 INCYTE. 238
15.14.1 COMPANY SNAPSHOT 238
15.14.2 REVENUE ANALYSIS 238
15.14.3 PRODUCT PORTFOLIO 239
15.14.4 RECENT DEVELOPMENTS 239
15.15 LILLY. 240
15.15.1 COMPANY SNAPSHOT 240
15.15.2 REVENUE ANALYSIS 241
15.15.3 PRODUCT PORTFOLIO 241
15.15.4 RECENT DEVELOPMENTS 242
15.16 NOVARTIS AG 243
15.16.1 COMPANY SNAPSHOT 243
15.16.2 REVENUE ANALYSIS 243
15.16.3 PIPELINE PORTFOLIO 244
15.16.4 PRODUCT PORTFOLIO 244
15.16.5 RECENT DEVELOPMENTS 244
15.17 PFIZER INC. 245
15.17.1 COMPANY SNAPSHOT 245
15.17.2 REVENUE ANALYSIS 245
15.17.3 PRODUCT PORTFOLIO 246
15.17.4 RECENT DEVELOPMENTS 246
16 QUESTIONNAIRE 247
17 RELATED REPORTS 251
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