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Report

Neurostimulation: Technologies and Global Markets

Market Research Report I 2023-09-06 I 160 Pages I BCC Research

Description

Report Scope:

This report provides a comprehensive study of the global market for neurostimulation technologies and devices. It provides a detailed description of the different types of neurostimulation technologies and devices (invasive and noninvasive) and their current and historical market revenues.

Neurostimulation technologies and devices include spinal cord stimulation, deep brain stimulation, sacral nerve stimulation, vagus nerve stimulation, hypoglossal nerve stimulation, transcutaneous electrical nerve stimulation, transcranial magnetic stimulation and others.

This report also covers in detail the therapeutic applications of neurostimulation technologies and devices, including chronic pain, Parkinson's disease, epilepsy, urinary and fecal incontinence, obstructive sleep apnea, essential tremor, obsessive compulsive disorder, major depressive disorder/clinical depression and others. An in-depth analysis of the global market for neurostimulation technologies and devices includes historical data and market projections by device type, therapeutic application and region.

Report Includes:

- 51 tables
- An overview of the global markets and technologies for neurostimulation
- Estimation of the market size and analyses of market trends, with data from 2020 to 2022, estimates for 2023 and projection of CAGR through 2028
- Description of Dorsal Root Ganglion (DRG) neurostimulator system and discussion on approved indications of stimulation therapy for various diseases
- Detailed description of various types of stimulation such as spinal cord stimulation, transcutaneous electrical nerve stimulation, deep brain stimulation, sacral nerve stimulation, Vagus nerve stimulation, hypoglossal nerve stimulation, and transcranial magnetic stimulation; and discussion on their mode of action and advantages
- Information on recent therapy improvements and new indications for use, and discussion on alternatives to traditional stimulation therapies
- Coverage of ongoing scientific discoveries and technological advances in neurostimulation technologies and insights into marketed and pipeline (R&D) products, product recalls and reimbursement policies
- Market share analysis of neurostimulation devices by application, type and region, and evaluation of market size and forecast, and detailed analysis of drivers, challenges and opportunities affecting market growth
- Market share analysis of the key companies of the industry and coverage of events like mergers & acquisitions, joint ventures, collaborations or partnerships, and other key market strategies
- Comprehensive company profiles of major players of the industry, including Axonics Inc., Boston Scientific Corp., Medtronic PLC, Synapse Biomedical Inc. and Xavant Technology

Executive Summary

Summary:

The human nervous system works as the chief commander of the human body. The medical science community has long believed that it has huge potential in treatment of human body disorders. Neurostimulation technology involves the alteration or modulation of nerves. Neurostimulation devices deliver electrical current or magnetic impulses directly to nerves in order to modify their activity.

Over the past 25 to 30 years, neurostimulation has emerged as one of the most dynamic fields of therapy, and has been actively investigated for treatment of a range of clinical conditions including chronic pain, movement disorders (Parkinson's disease, tremor, dystonia and others), epilepsy, psychiatric disorders, functional restoration, cardiovascular disorders, gastrointestinal disorders and genitourinary disorders. It is also said to consist of "drug-free solutions." Currently, the potential of neurostimulation technology is actively being explored for other clinical conditions including obesity, tinnitus and central nerve system disorders.

Given the vast size of the potential treatment population and the many ongoing scientific discoveries and technological advances in neurostimulation technologies, the market for neurostimulation devices market is poised for significant growth. For example, according to the World Health Organization (WHO), epilepsy is one of the most common neurological diseases, affecting around REDACTED million people around the world. According to the Centers for Disease Control (CDC), an estimated REDACTED million adults suffered from chronic pain in the U.S. in 2021, including REDACTED million adults who had high-impact chronic pain. Other factors expected to aid in the market boom include many countries' growing elderly populations and increasing trends toward the use of nondrug therapies, greater expectations for quality of life, and improved patient attitudes toward receiving medical attention.

Neurostimulation technologies represent a cutting-edge field in neuroscience and medical science, aiming to modulate the activity of the nervous system to treat a wide range of neurological and neuropsychiatric disorders. These innovative techniques involve the application of electrical, magnetic or optogenetic stimuli to specific areas of the brain or nervous system, offering the potential to alleviate symptoms, restore lost function and enhance cognitive capabilities. Neurostimulation is based on the concept of neuromodulation, where electrical signals are applied to neurons to alter their activity and influence neural networks. Neurons communicate through electrical impulses, and by selectively stimulating or inhibiting specific neural populations, neuroscientists and clinicians can modulate brain function.

Table of Contents
Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing the Study
What's New in This Update?
Scope of Report
Methodology and Information Sources
Regional Breakdown
Chapter 2 Summary and Highlights
Market Outlook
Chapter 3 Market and Technology Background
Overview of Neurostimulation
Types of Neurostimulation Technologies
Spinal Cord Stimulation
Deep Brain Stimulation
Sacral Nerve Stimulation (SNS)
Vagus Nerve Stimulation
Hypoglossal Nerve Stimulation
Transcutaneous Electrical Nerve Stimulation
Transcranial Magnetic Stimulation (TMS)
Other Neurostimulation Technologies
Therapeutic Applications for Neurostimulation
Chronic Pain Management
Neurological Disorders
Urinary and Fecal Incontinence
Obstructive Sleep Apnea
Chronic Migraine and Headache
Cardiovascular Diseases
Gastrointestinal Disorders
Obesity
Psychiatric Disorders
Technological Developments
MRI Compatibility
Rechargeable and Non-rechargeable Devices
Chapter 4 Market Dynamics
Market Trends
Drivers
Market Restraints
Chapter 5 Market Breakdown by Technology/Device Type
Global Market for Neurostimulation Devices by Type
Spinal Cord Stimulation (SCS) Devices
Transcutaneous Electrical Nerve Stimulation (TENS) Devices
Deep Brain Stimulation (DBS) Devices
Sacral Nerve Stimulation (SNS) Devices
Vagus Nerve Stimulation (VNS) Devices
Hypoglossal Nerve Stimulation (HGNS) Devices
Market Size and Forecast
Transcranial Magnetic Stimulation (TMS) Devices
Other Types of Neurostimulation Devices
Chapter 6 Market Breakdown by Therapeutic Application
Global Market for Neurostimulation Devices by Therapeutic Application
Chronic Pain
Urinary and Fecal Incontinence
Parkinson's Disease
Epilepsy
Obstructive Sleep Apnea (OSA)
Essential Tremor
Major Depressive Disorder (MDD)/Clinical Depression
Obsessive Compulsive Disorder (OCD)
Other Therapeutic Applications
Chapter 7 Market Breakdown by Region
Global Market for Neurostimulation Devices by Region
North America
Europe
Asia-Pacific
Rest of the World
Chapter 8 Regulatory Structure
Regulatory Framework
U.S.
European Union
Japan
Chapter 9 Key Products and Technologies on the Market
Recent Therapeutic Improvements and New Indications
Spinal Cord Stimulation
Deep Brain Stimulation
Sacral Nerve Stimulation (SNS)
Axonics
Medtronic
Vagus Nerve Stimulation
Hypoglossal Nerve Stimulation
Transcutaneous Electrical Nerve Stimulation
Transcranial Magnetic Stimulation
Other Types of Stimulation
New Indications and Neurostimulation Therapies
Chapter 10 Emerging Technologies and Developments
Emerging Technologies and Developments
Closed-Loop Neurostimulation
Non-Invasive Brain Stimulation Techniques
High-Frequency Stimulation
Magnetic Resonance-guided Focused Ultrasound
Optogenetics
Bioelectronic Medicine
Wireless and Remote-Controlled Devices
Chapter 11 Recent M&A
M&A in the Neurostimulation Technologies Industry
Chapter 12 Competitive Landscape
Company Market Shares by Product Segment
Spinal Cord Stimulation Devices
Deep Brain Stimulation Devices
Sacral Nerve Stimulation Devices
Vagus Nerve Stimulation Devices
Hypoglossal Nerve Stimulation Devices
Transcranial Magnetic Stimulation Devices
Transcutaneous Electrical Nerve Stimulation Devices
Recent Industry Activities
Chapter 13 Company Profiles
ABBOTT LABORATORIES
ALEVA NEUROTHERAPEUTICS SA
AVERY BIOMEDICAL DEVICES INC.
AXONICS INC.
BIOINDUCTION LTD.
BIOVENTUS LLC
BIOWAVE CORP.
BOSTON SCIENTIFIC CORP.
BRAINSWAY LTD.
COCHLEAR AMERICAS
CVRX INC.
ELECTROCORE INC.
INSPIRE MEDICAL SYSTEMS INC.
INTEGER HOLDINGS CORP.
LABORIE INC.
LIVANOVA PLC
MAG & MORE GMBH
MAGSTIM INC.
MEDTRONIC PLC
NALU MEDICAL INC.
NEUROMED CONSULTING INC.
NEUROMETRIX INC.
NEURONETICS INC.
NEUROPACE INC.
NEUROSIGMA INC.
NEUROVALENS LTD.
NEVRO CORP.
NEXSTIM PLC
NYXOAH SA
SOTERIX MEDICAL INC.
SYNAPSE BIOMEDICAL INC.
XAVANT TECHNOLOGY (PTY) LTD.
ZOLL MEDICAL CORP.
Chapter 14 Appendix: Acronyms

List of Tables
Summary Table : Global Market for Neurostimulation Devices, by Type, Through 2028
Table 1 : Prevalence of Chronic Pain and High-Impact Chronic Pain Among U.S. Adults, by Sociodemographic Characteristics, 2016
Table 2 : Type of Chronic Pain, U.S
Table 3 : Prevalence of Adult Overweight and Obese Population, by Country, 2014-2022
Table 4 : Global Market for Neurostimulation Devices, by Type, Through 2028
Table 5 : Global Market for SCS Devices, by Region, Through 2028
Table 6 : Global Market for TENS Devices, by Region, Through 2028
Table 7 : Global Market for DBS Devices, by Region, Through 2028
Table 8 : Global Market for SNS Devices, by Region, Through 2028
Table 9 : Global Market for VNS Devices, by Region, Through 2028
Table 10 : Global Market for HGNS Devices, by Region, Through 2028
Table 11 : Global Market for TMS Devices, by Region, Through 2028
Table 12 : Global Market for Other Types of Neurostimulation Devices, by Region, Through 2028
Table 13 : Global Market for Neurostimulation Devices, by Therapeutic Application, Through 2028
Table 14 : Global Market for Neurostimulation Devices, by Region, Through 2028
Table 15 : Regulatory Approval: U.S. vs. Europe
Table 16 : Implantable Neurostimulation Devices Approved, January 2018-May 2023
Table 17 : Currently Available Spinal Cord Stimulation Systems
Table 18 : Currently Available Deep Brain Stimulation Systems
Table 19 : Currently Available Sacral Nerve Stimulation Systems
Table 20 : Currently Available Vagus Nerve Stimulation Systems
Table 21 : FDA-Approved TENS Systems for Pain Relief Treatment, 2015-2021
Table 22 : FDA-Approved TENS Systems for Treatment of Migraine Pain Relief, 2015-2021
Table 23 : Currently Available Phrenic Nerve Stimulation Systems for Respiratory Insufficiency
Table 24 : Currently Available HGNS Systems for Respiratory Insufficiency
Table 25 : Currently Available Peripheral Nerve Stimulation Systems
Table 26 : Currently Available Transcranial Magnetic Stimulating Systems
Table 27 : Currently Available Gastric Electrical Stimulation Systems
Table 28 : Neurostimulation Stimulation Product Pipeline
Table 29 : Active Clinical Trials on Spinal Cord Stimulation Technology
Table 30 : Active Clinical Trials on DBS Technology
Table 31 : Active Clinical Trials on VNS Technology
Table 32 : Active Clinical Trials on Sacral Nerve Stimulation Technology
Table 33 : Active Clinical Trials on Peripheral Nerve Stimulation Technology
Table 34 : Active Clinical Trials on Hypoglossal Nerve Stimulation Technology
Table 35 : Shares of Companies in the Global Market for SCS Devices, 2022
Table 36 : Shares of Companies in the Market for DBS Devices, 2022
Table 37 : Aleva Neurotherapeutics SA: News
Table 38 : Axonics Inc.: Annual Revenue, 2022
Table 39 : Axonics Inc.: News
Table 40 : Axonics Inc.: Product Portfolio
Table 41 : Bioventus LLC: Annual Revenue, 2022
Table 42 : Bioventus LLC: News
Table 43 : Bioventus LLC: Product Portfolio
Table 44 : Boston Scientific Corp.: Annual Revenue, 2022
Table 45 : Boston Scientific Corp.: News
Table 46 : Boston Scientific Corp.: Product Portfolio
Table 47 : Medtronic PLC: Annual Revenue, 2022
Table 48 : Synapse Biomedical Inc.: News
Table 49 : Xavant Technology: Product Portfolio
Table 50 : Acronyms Used in This Report

List of Figures
Summary Figure : Global Market for Neurostimulation Devices, by Type, 2020-2028
Figure 1 : Global Market Shares of Neurostimulation Devices, by Type, 2022
Figure 2 : Global Market for SCS Devices, by Region, 2020-2028
Figure 3 : Global Market for TENS Devices, by Region, 2020-2028
Figure 4 : Global Market for DBS Devices, by Region, 2020-2028
Figure 5 : Global Market for SNS Devices, by Region, 2020-2028
Figure 6 : Global Market for VNS Devices, by Region, 2020-2028
Figure 7 : Global Market for HGNS Devices, by Region, 2020-2028
Figure 8 : Global Market for TMS Devices, by Region, 2020-2028
Figure 9 : Global Market for Other Types of Neurostimulation Devices, by Region, 2020-2028
Figure 10 : Global Market Shares of Neurostimulation Devices, by Therapeutic Application, 2022
Figure 11 : Global Market Shares of Neurostimulation Devices, by Region, 2022
Figure 12 : Shares of Leading Companies in the Global Market for SCS Devices, 2022
Figure 13 : Shares of Companies in the Market for DBS Devices, 2022
Figure 14 : Abbott: Diagnostics Revenue, 2020-2022
Figure 15 : Abbott: Diagnostics Market Share, by Business Segment, 2022
Figure 16 : Abbott: Revenue Shares, by Business Unit, 2021
Figure 17 : Abbott: Revenue Shares, by Market, 2021
Figure 18 : Axonics Inc.: Annual Revenue, 2021 and 2022
Figure 19 : Axonics Inc.: Revenue Shares, by Business Unit, 2022
Figure 20 : Axonics Inc.: Revenue Shares, by Country/Region, 2022
Figure 21 : Bioventus LLC: Annual Revenue, 2021 and 2022
Figure 22 : Bioventus LLC: Revenue Shares, by Business Unit, 2022
Figure 23 : Bioventus LLC: Revenue Shares, by Country/Region, 2022
Figure 24 : Boston Scientific Corp.: Annual Revenue, 2021 and 2022
Figure 25 : Boston Scientific Corp.: Revenue Shares, by Business Unit, 2022
Figure 26 : Boston Scientific Corp.: Revenue Shares, by Country/Region, 2022
Figure 27 : Medtronic PLC: Annual Revenue, 2021 and 2022
Figure 28 : Medtronic PLC: Revenue Shares, by Business Unit, 2022
Figure 29 : Medtronic PLC: Revenue Shares, by Country/Region, FY2023

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