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Report

Laboratory Animal Models, 3D Cultures and Organoids

Market Research Report I 2019-03-08 I 198 Pages I BCC Research

Description

Report Scope:

The report describes three global markets: the animal model market, the 3D cultures market and the organoid market. The organoid market is described in more detail in a separate chapter of the report.

Report Includes:

- 49 data tables 16 additional tables
- Comprehensive overview of the global markets for laboratory animal models, 3D cell cultures and organoids
- Analyses of global market trends, with data from 2016, 2017 and 2018; estimates for 2019 to 2022; and projections of compound annual growth rates (CAGRs) through 2023
- Country specific data and analysis for Australia, China, Japan, U.S., Canada, Mexico, Brazil, U.K., France, Germany, Israel and Middle East
- Information on current trends that significantly affect the basic research, biomedical and other industries where animals are used for toxicity testing and for evaluating the safety and metabolism of chemical compounds
- Discussion of most significant trends in the 3D cell culture industry, including the bioprinting, organ-on-chip and organoid segments
- Review of selected patents and patent applications on laboratory animal models for a brief period of 2006 to 2018
- Company profiles of major market players within the industry, including Charles River Laboratories, Envigo, Crown Bioscience Inc., Genoway S.A., Taconic Biosciences and Merck & Co., Inc.

Executive Summary

Scope of Report

The report describes three global markets: the animal model market, the 3D cultures market and the organoid market. The organoid market is described in more detail in a separate chapter of the report.

Reasons for Doing This Study

The current market is at a point where a shift from classical laboratory animal models to new 3D cell culture-based technologies is occurring. Determining the key factors involved in this shift is crucial for identifying future trends in these partly interconnected industries. Animal model companies need to know the current threats to their business and how to adapt to them. They also need to know which segments will continue to be strong domains for laboratory animals in upcoming years. The report describes the complete market landscape for laboratory animal models.

For companies involved in 3D cultures, the report provides insights into the most promising segments to focus on to help speed up academic research or for new drug development. The study's wide scope compares all three available technologies and offers the overall picture in a single detailed report.

Table of Contents
Chapter 1 Introduction
Background
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources and Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports
Chapter 2 Summary and Highlights
Laboratory Animal Models
3D Cell Cultures
Chapter 3 Animal Model Market Technology Background
Methods of Animal Model and 3D Cell Culture Modification
Physical and Chemical Mutations
Targeted Mutations
Laboratory Animal Models
Market Definition
Animal Model Lines
Common Species of Laboratory Animals
Current Trends in Animal Model Usage
Chapter 4 3D Cell Cultures Market Breakdown by Technology
3D Cell Cultures
Spheroids
3D Cultures vs. 2D Cultures vs. 2.5D Cultures
Scaffold-Based and Scaffold-Free 3D Cell Cultures
Scaffold-Free 3D Cell Cultures
Scaffold-Based 3D Cell Cultures
Tissue Engineering and Bioprinting
3D Bioprinting Technology
Microfluidic Organ-on-Chip Platforms
Types of Organ-on-Chip Devices
Chapter 5 Organoids Market Breakdown by Technology
Organoids
Introduction
Organoids Technology and Principles
Organoid Technology Timeline
Types of Organoids
Organoid Biobanking and Libraries
Organoid System Complexity
Chapter 6 Market Breakdown by End User
Animal Models by End User
Academia and Research Institutions
Biomedical and Pharmaceutical Companies
Regulatory Processes and Routine Production
Cosmetics Industry
3D Cell Cultures by End User
Basic Research
Biomedical and Pharma Companies
Regulatory Processes and Routine Production
Cosmetics Industry
Chapter 7 Market Breakdown by Application
Drug Discovery, Cancer Research and Personalized Medicine
Drug Discovery and High-throughput Compound Screening
Cancer Research
Personalized Medicine
Regenerative Medicine and Transplantations
Toxicity and Safety Testing
Drug Toxicity Testing
Chapter 8 Market Breakdown by Region
Asia-Pacific (APAC)
Australia
China
Japan
North America
U.S.
Canada
Mexico
Europe
Great Britain
Germany
France
Rest of Europe
Middle East and Africa (MEA)
Israel
South America
Brazil
Chapter 9 Patent Review/New Developments
Chapter 10 Analysis of Market Opportunities
Market Opportunities: Animal Models
Market Opportunities: 3D Cell Culture Segment
Organs-on-Chip
Organoids
Bioprinting
Advantages and Disadvantages of 3D Cell Cultures and Animal Models
Animal Models
3D Cell Cultures in General
Organoids
Organs-on-Chip
Chapter 11 Profiles of Companies and Important Institutions
Animal Model Companies
ALPHAGENESIS INC.
CHARLES RIVER LABORATORIES INTERNATIONAL INC.
COVANCE INC.
CROWN BIOSCIENCE INC.
ENVIGO
GENOWAY S.A.
JACKSON LABORATORY
JANVIER LABS
OAK HILL GENETICS
PRIMGEN
TACONIC BIOSCIENCES
TRANSGENIC INC.
TRANSPOSAGEN BIOPHARMACEUTICALS INC.
Bioprinting and Regenerative Medicine Companies
ALLEVI
ASPECT BIOSYSTEMS LTD.
BIOINK SOLUTIONS INC.
CELLINK INC.
COLLPLANT HOLDINGS LTD.
EAST RIVER BIOSOLUTIONS/XYLYX BIO
EPIBONE
MATTEK CORP.
NANO 3D BIOSCIENCES INC.
ORGANOVO HOLDINGS INC.
PEPGEL LLC
REGENHU
TEVIDO BIODEVICES INC.
TISSUSE GMBH
Organ-on-Chip Companies
AXOSIM
EMULATE, INC.
KIRKSTALL LTD.
MICRONIT MICROTECHNOLOGIES
MIMETAS
TARA BIOSYSTEMS INC.
Organoid Companies
3DNAMICS
CELLESCE
CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER
HUBRECHT ORGANOID TECHNOLOGY
QGEL
R&D SYSTEMS INC.
STEMCELL TECHNOLOGIES INC.
TREVIGEN INC.
Other 3D Cell Culture Companies
3D BIOTEK LLC
ADVANCED BIOMATRIX INC.
HORIZON DISCOVERY GROUP PLC
IN SPHERO INC.
MERCK & CO., INC.
PROMOCELL GMBH
REPROCELL INC.
SYNTHECON, INC.

List of Tables
Summary Table A : Global Market for Laboratory Animal Models, by Type, Through 2023
Summary Table B : Global Market for Organs-on-Chips and Organoids, Through 2023
Table 1 : Global Market for Laboratory Mice, by Region, Through 2023
Table 2 : Global Market for Laboratory Rats, by Region, Through 2023
Table 3 : Global Market for Laboratory Guinea Pigs, by Region, Through 2023
Table 4 : Global Market for Laboratory Rabbits, by Region, Through 2023
Table 5 : Global Market for Laboratory Hamsters, by Region, Through 2023
Table 6 : Global Market for Laboratory Cats, by Region, Through 2023
Table 7 : Global Market for Laboratory Dogs, by Region, Through 2023
Table 8 : Global Market for Laboratory Pigs, by Region, Through 2023
Table 9 : Global Market for Laboratory Nonhuman Primates, by Region, Through 2023
Table 10 : Tissue Engineering Related Search Terms in PubMed, Through 2018
Table 11 : Tissue Bioprinting Related Search Terms in PubMed, Through 2018
Table 12 : Organ-on-Chip Related Search Terms in PubMed, Through 2018
Table 13 : Investments in Organ-on-Chip Technology, by Company, Through 2018
Table 14 : Global Market for Organs-on-Chips, Through 2023
Table 15 : Organoid Types Mentioned in PubMed Articles, Through 2018
Table 16 : Mentions of Spheroids in PubMed Articles, Through 2018
Table 17 : Organoid Centers
Table 18 : Global Market for Organoids, by Type, Through 2023
Table 19 : Global Market for Animal Models, by End User, Through 2023
Table 20 : Continents Banning Animal Testing for Cosmetics, by Country and Year Banned, 2013-2019
Table 21 : Asia-Pacific Market for Laboratory Animal Models, by Type, Through 2023
Table 22 : Australian Market for Laboratory Animal Models, by Type, Through 2023
Table 23 : Chinese Market for Laboratory Animal Models, by Type, Through 2023
Table 24 : Japanese Market for Laboratory Animal Models, by Type, Through 2023
Table 25 : North American Market for Laboratory Animal Models, by Type, Through 2023
Table 26 : U.S. Market for Laboratory Animal Models, by Type, Through 2023
Table 27 : Canadian Market for Laboratory Animal Models, by Type, Through 2023
Table 28 : Mexican Market for Laboratory Animal Models, by Type, Through 2023
Table 29 : European Market for Laboratory Animal Models, by Type, Through 2023
Table 30 : Great Britain Market for Laboratory Animal Models, by Type, Through 2023
Table 31 : German Market for Laboratory Animal Models, by Type, Through 2023
Table 32 : French Market for Laboratory Animal Models, by Type, Through 2023
Table 33 : Rest of European Market for Laboratory Animal Models, by Type, Through 2023
Table 34 : Middle Eastern and African Market for Laboratory Animal Models, by Type, Through 2023
Table 35 : Israeli Market for Laboratory Animal Models, by Type, Through 2023
Table 36 : South American Market for Laboratory Animal Models, by Type, Through 2023
Table 37 : Brazilian Market for Laboratory Animal Models, by Type, Through 2023
Table 38 : Review of Selected Patents and Patent Applications on Laboratory Animal Models, 2006-2018
Table 39 : Global Number of Transplanted Organs, by Country, 2017
Table 40 : Charles River Laboratories: Segments
Table 41 : Charles River Laboratories: Revenue, 2013-2017
Table 42 : Charles River Laboratories: RMS Company Yearly Revenues/Operating Income, by Quarter, 2016 and 2017
Table 43 : Charles River Laboratories: Company Business Structure Data, by Segment, 2017
Table 44 : Crown Bioscience Inc.: Segments
Table 45 : Envigo: Segments
Table 46 : Envigo: Consolidated Revenue, by Segment, 2015-2018
Table 47 : Envigo: RMS Quarterly Revenue, 2015-2018
Table 48 : Envigo: Types of Laboratory Animals
Table 49 : Genoway S.A.: Segments
Table 50 : Genoway S.A.: Sales, 2016 and 2017
Table 51 : Jackson Laboratory: Segments
Table 52 : Jackson Laboratory: Company Data, 2013-2016
Table 53 : Janvier Labs: Segments
Table 54 : Taconic Biosciences: Segments
Table 55 : Transgenic Inc.: Segments
Table 56 : Transgenic Inc.: Company Data, 2014-2018
Table 57 : Transposagen Biopharmaceuticals Inc.: Segments
Table 58 : Organovo: Expenses on R&D, 2013-2018
Table 59 : 3D Biotek LLC: Segments
Table 60 : In Sphero Inc.: Segments
Table 61 : Merck & Co., Inc.: Revenue, by Region
Table 62 : Merck & Co., Inc.: Company Data, 2013-2017
Table 63 : Reprocell Inc.: Acquisitions

List of Figures
Summary Figure A : Global Market for Laboratory Animal Models, by Type, 2016-2023
Summary Figure B : Global Market for Organ-on-Chip and Organoids, 2017-2023
Figure 1 : PubMed Timeline for the Mesh Terms of Types of Mice, 2000-2017
Figure 2 : Global Market for Laboratory Mice, by Region, 2016-2023
Figure 3 : PubMed Timeline for the Mesh Terms of Types of Rats, 2000-2017
Figure 4 : Global Market for Laboratory Rats, by Region, 2016-2023
Figure 5 : Global Market for Laboratory Guinea Pigs, by Region, 2016-2023
Figure 6 : Global Market for Laboratory Rabbits, by Region, 2016-2023
Figure 7 : Global Market for Laboratory Hamster, by Region, 2016-2023
Figure 8 : Global Market for Laboratory Cats, by Region, 2016-2023
Figure 9 : Global Market for Laboratory Dogs, by Region, 2016-2023
Figure 10 : Global Market for Laboratory Pigs, by Region, 2016-2023
Figure 11 : Global Market for Laboratory Nonhuman Primates, by Region, 2016-2023
Figure 12 : Tissue Engineering Related Search Terms in PubMed, 2010-2018
Figure 13 : Tissue Bioprinting Related Search Terms in PubMed, 2010-2018
Figure 14 : Timeline for Possible Availability of 3D Printed Organs and Tissues for Humans, 2018-2043
Figure 15 : Organ-on-Chip Related Search Terms in PubMed, 2010-2018
Figure 16 : Investments in Organ-on-Chip Technology, by Company, 2008-2018
Figure 17 : Global Market for Organs-on-Chips, 2017-2023
Figure 18 : Timeline for Possible Availability of Organ-on-Chip Devices for Drug Screening in Human Patients, 2018-2030
Figure 19 : Organoid Types Mentioned in PubMed Articles, 2010-2018
Figure 20 : Mentions of Spheroids in PubMed Articles, 2010-2018
Figure 21 : Global Market for Organoids, by Type, 2017-2023
Figure 22 : Global Market for Animal Models, by End User, 2016-2023
Figure 23 : Asia-Pacific Market for Laboratory Animal Models, by Type, 2016-2023
Figure 24 : Australian Market for Laboratory Animal Models, by Type, 2016-2023
Figure 25 : Chinese Market for Laboratory Animal Models, by Type, 2016-2023
Figure 26 : Japanese Market for Laboratory Animal Models, by Type, 2016-2023
Figure 27 : North American Market for Laboratory Animal Models, by Type, 2016-2023
Figure 28 : U.S. Market for Laboratory Animal Models, by Type, 2016-2023
Figure 29 : U.S. National Toxicology Program Funding for Toxicity Testing, 2013-2018
Figure 30 : Canadian Market for Laboratory Animal Models, by Type, 2016-2023
Figure 31 : Mexican Market for Laboratory Animal Models, by Type, 2016-2023
Figure 32 : European Market for Laboratory Animal Models, by Type, 2016-2023
Figure 33 : Great Britain Market for Laboratory Animal Models, by Type, 2016-2023
Figure 34 : German Market for Laboratory Animal Models, by Type, 2016-2023
Figure 35 : French Market for Laboratory Animal Models, by Type, 2016-2023
Figure 36 : Rest of European Market for Laboratory Animal Models, by Type, 2016-2023
Figure 37 : Middle Eastern and African Market for Laboratory Animal Models, by Type, 2016-2023
Figure 38 : Israeli Market for Laboratory Animal Models, by Type, 2016-2023
Figure 39 : South American Market for Laboratory Animal Models, by Type, 2016-2023
Figure 40 : Brazilian Market for Laboratory Animal Models, by Type, 2016-2023
Figure 41 : Global Number of Transplanted Organs, by Country, 2017
Figure 42 : Charles River Laboratories: Number of Employees
Figure 43 : Charles River Laboratories: RMS Company Yearly Revenues/Operating Income, by Quarter, 2016 and 2017
Figure 44 : Charles River Laboratories: Revenue Share, by Segment, 2017
Figure 45 : Envigo: Consolidated Revenue, by Segment, 2015-2018
Figure 46 : Envigo: RMS Quarterly Revenue, 2015-2018
Figure 47 : Merck & Co., Inc.: Revenue, by Region

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