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Report
Global primary cells market trends and forecasts
Market Reseach Report I 2022-10-12 I 108 Pages I BCC Research
Description
Report Scope:
This report aims to provide a comprehensive study of the global market for primary cells, both in terms of quantitative and qualitative data, to help develop business/growth strategies, assess the market landscape, analyze their position in the current marketplace, and make informed business decisions regarding primary cells. Segmentation is based on biological source type, tissue source type, application, end user, and region.
Industry growth drivers, restraints, trends, and opportunities in the primary cells market are also discussed in detail. The report also provides information on the competitive landscape, elaborative company profiles, and the impact of COVID-19 on the market.
Report Includes:
- 30 tables
- A comprehensive overview of the global market for primary cells
- Analyses of the global and regional market trends, with historic market revenue from 2019 to 2021, estimates for 2022, and projections of compound annual growth rates (CAGRs) through 2027
- Highlights of the upcoming market potential for primary cells, growth driving factors, and areas of focus to forecast this market into various segments and sub-segments
- Estimation of the actual market size and revenue forecast for primary cells market in USD million terms, and corresponding market share analysis based on product type, product origin, application, end user, and region
- Discussion of the industry value chain analysis providing a systematic study of key intermediaries involved, with emphasis on manufacturers, suppliers, and major types of end users
- Identification of the companies that are best positioned to meet the demand for primary cells because of their proprietary technologies, strategic alliances, or other advantages
- Analysis of the vendor landscape based on their recent developments, financials, and segmental revenues
- Descriptive company profiles of the leading global players, including Charles River Laboratories, Lonza, Merck KGaA and Thermo Fisher Scientific
Executive Summary
Summary:
Primary cells are cells isolated directly from living tissue (e.g., biopsy material) and maintained for growth in vitro under optimized culture conditions. Primary cells can be categorized according to the genus from which they are isolated, as well as by species or tissue type. Epithelial cells, fibroblasts, keratinocytes, melanocytes, endothelial cells, muscle cells, hematopoietic cells, and mesenchymal stem cells are the most frequently used in primary cell types.
Since primary cells are non-transformed, non-immortalized cells directly derived from tissue, they most closely represent the tissue of origin. These cells have undergone very few population doublings. Therefore, they provide excellent model systems for studying the normal physiology and biochemistry of cells (e.g., metabolic studies, aging, signaling studies), the effects of drugs and toxic compounds on the cells, and mutagenesis and carcinogenesis.
Primary cell isolation is a tedious and time-consuming task. Due to the difficulties in obtaining tissue samples and successfully isolating primary human cells, ready-to-useprimary cells have become increasingly popular. Harmonized cell culture media and reagents are essential to support optimal, consistent primary cell growth and maintain the tissue-specific characteristics to ensure the experiment's reliability and validity. Improvements in cell isolation and cryopreservation, optimized media, and reagents, and streamlined use protocols have contributed to the explosion of primary cell use in research programs globally. Commercial primary cell providers are bridging the gap to enable
scientists to leverage their time and resources to focus on their own R&D.
Demand for primary cells is increasing globally, with a drive toward effective and efficient cell cultures for basic and applied research. Human primary cells are increasingly being used in basic research, and drug discovery and development. Other applications driving the growth of this market include 3D cell culture, cell therapy, and personalized medicine research. As regulatory bodies around the globe increase scrutiny on the selection of animal models, there is greater utilization of in vitro models using human primary cells for drug screening and toxicology and pharmacology studies. The scarcity of tissue samples and evolving legal and ethical regulatory frameworks are the key factors hindering the primary cells market to achieve its full growth potential.
The global market for primary cells was valued at REDACTED in 2021. The market is projected to reach REDACTED in 2027, growing at a CAGR of REDACTED through the forecast p eriod.
Table of Contents
Chapter 1 Introduction
1.1 Study Goals and Objectives
1.2 Reasons for Doing This Study
1.3 Scope of Report
1.4 Methodology Information Sources
1.5 Geographic Breakdown
1.6 Analyst's Credentials
1.7 BCC Custom Research
1.8 Related BCC Research Reports
Chapter 2 Summary and Highlights
Chapter 3 Market and Technology Background
3.1 Cell
3.2 Cell Culture
3.3 Cell Lines
3.4 Primary Cells
3.5 Primary Cells vs. Cell Lines
3.6 Primary Cell Culture
3.6.1 Primary Cell Culture Media and Supplements
3.7 Characterization of Primary Cells
3.8 Primary Cell Culture Applications
Chapter 4 Market Dynamics
4.1 Market Drivers
4.1.1 Increasing Incidence of Chronic Diseases
4.1.2 Demand for Effective Drug Discovery and Development Process
4.1.3 Minimizing Animal Testing
4.1.4 Advances in Primary Cells Culture Technologies
4.1.5 Growing Spending on Pharmaceutical R&D
4.1.6 Strong Biotech Funding
4.1.7 Growing Applications in 3D Cell Culture Models
4.1.8 Growing Focus on Personalized Medicine
4.1.9 Growing Demand in Cell Therapy Research
4.2 Market Restraints
4.2.1 Demanding Requirements of Primary Cells
4.2.2 Donor Tissue Supply Issues
4.2.3 Ethical and Regulatory Concerns
4.3 Market Trends
4.3.1 Growing Demand for HLA-Typed Human Primary Cells
4.3.2 Impact of COVID- 19
Chapter 5 Market Breakdown by Biological Source Type
5.1 Introduction
5.1.1 Animal Primary Cells
5.1.2 Human Primary Cells
5.2 Global Market for Primary Cells by Biological Source
Chapter 6 Market Breakdown by Tissue Source Type
6.1 Primary Hematopoietic/Blood and Immune Cells
6.1.1 Overview
6.1.2 Hematopoietic Stem Cells (HSCs)
6.1.3 Applications
6.2 Primary Dermatocytes/Skin Cells
6.2.1 Overview
6.2.2 Applications
6.3 Gastrointestinal Cells
6.3.1 Overview
6.3.2 Applications
6.4 Primary Liver Cells/Hepatocytes
6.4.1 Overview
6.4.2 Applications
6.5 Primary Lung/Airway Cells
6.5.1 Overview
6.5.2 Applications
6.6 Renal/Kidney Cells
6.6.1 Overview
6.6.2 Applications
6.7 Primary Heart/Cardiac Cells
6.7.1 Overview
6.7.2 Applications
6.8 Musculoskeletal Cells
6.8.1 Overview
6.8.2 Applications
6.9 Other Primary Cells
6.9.1 Primary Brain Cells
6.9.2 Primary Brain Cells Applications
6.9.3 Other Primary Cells
6.10 Global Market for Primary Cells by Tissue Source Type
6.10.1 Primary Hematopoietic/Blood and Immune Cells
6.10.2 Primary Dermatocytes/Skin Cells
6.10.3 Primary Gastrointestinal Cells
6.10.4 Primary Liver Cells/Hepatocytes
6.10.5 Primary Lung/Airway Cells
6.10.6 Primary Renal/Kidney Cells
6.10.7 Primary Heart/Cardiac Cells
6.10.8 Primary Musculoskeletal Cells
6.10.9 Other Primary Cells
Chapter 7 Market Breakdown by End User
7.1 Overview
7.2 Global Market for Primary Cells by End User Type
7.2.1 Life Science Research Companies
7.3 Academic and Other Research Institutes
Chapter 8 Market Breakdown by Application
8.1 Overview
8.2 Basic Research
8.3 Drug Discovery
8.4 ADME, Toxicology and Safety Assessment Studies
8.4.1 ADME and Toxicology Studies
8.4.2 Safety Assessment Studies
8.5 Cell Therapy Research
8.5.1 Basic Research
8.5.2 Drug Discovery
8.5.3 Cell Therapy Research
Chapter 9 Market Breakdown by Region
9.1 Global Market for Primary Cells by Region
9.2 North America
9.2.1 Market Revenue, by Tissue Source Type
9.2.2 Market Revenue, by Country
9.3 Europe
9.3.1 Market Revenue by Tissue Source Type
9.3.2 Market Revenue, by Country
9.4 Asia-Pacific
9.4.1 Market Revenue by Tissue Source Type
9.5 Rest of the World (RoW)
9.5.1 RoW Primary Cells Market by Tissue Source Type
Chapter 10 Competitive Landscape
10.1 Overview
Chapter 11 Company Profiles
AMERICAN TYPE CULTURE COLLECTION
BIOIVT
CELL APPLICATIONS INC.
CELL BIOLOGICS
CHARLES RIVER LABORATORIES
DISCOVERY LIFE SCIENCES
LIFENET HEALTH
LONZA
MERCK KGAA
PELOBIOTECH GMBH
PROMOCELL GMBH
SCIENCELL RESEARCH LABORATORIES
THERMO FISHER SCIENTIFIC INC.
ZENBIO INC.
List of Tables
Summary Table : Global Market for Primary Cells, by Biological Source Type, Through 2027
Table 1 : Advantages and Disadvantages of Primary Cells
Table 2 : Primary Cells vs. Cell Lines
Table 3 : Clinical Trials Initiated Between 2015 and 2021, by Condition
Table 4 : Biotech Funding (Capital Markets/IPOs/VCs), 2005-09 vs. 2020
Table 5 : Global Market for Primary Cells, by Biological Source Type, Through 2027
Table 6 : Relative Percentage of Each Immune Cell Type in Peripheral Blood Mononuclear Cells (PMBCs)
Table 7 : Primary Cells by Tissue Source Type
Table 8 : Global Market for Primary Cells, by Tissue Source Type, Through 2027
Table 9 : NIH Funding for Neuroscience Research, by Year
Table 10 : Global Market for Primary Cells, by End User Type, Through 2027
Table 11 : Drug Discovery and Development Workflow
Table 12 : Commonly Used Primary Cells for ADME, Toxicology, and Safety Assessment Studies
Table 13 : Applications of Primary Cells in Drug Discovery and Development
Table 14 : Stem Cell Uses in Research
Table 15 : U.S. NIH Funding for Various Stem Cell Research (SCR) Areas, 2014-2023
Table 16 : Global Market for Primary Cells, by Application Type, Through 2027
Table 17 : Total Financing for Regenerative Medicine, by Therapeutic Area
Table 18 : Global Market for Primary Cells, by Region, Through 2027
Table 19 : North American Market for Primary Cells, by Tissue Source Type, Through 2027
Table 20 : North American Primary Cells Market, by Country, Through 2027
Table 21 : NIH Funding for Selected Research Categories, by Year
Table 22 : European Market for Primary Cells, by Tissue Source Type, Through 2027
Table 23 : European Primary Cells Market, by Country, Through 2027
Table 24 : Number of Companies in the Life Sciences and Pharmaceutical Industry, with R&D Expenditure in Europe in 2019, by Country
Table 25 : Asia-Pacific Market for Primary Cells, by Tissue Source Type, Through 2027
Table 26 : Asia-Pacific Primary Cells Market, by Country, Through 2027
Table 27 : Gross Domestic Spending on R&D, by Country, Through 2019
Table 28 : RoW Market for Primary Cells, by Tissue Source Type, Through 2027
Table 29 : Competitive Analysis of Primary Cell Manufacturers/Suppliers, 2021
List of Figures
Summary Figure : Global Market for Primary Cells, by Biological Source Type, 2019-2027
Figure 1 : Basic Steps Used to Isolate Cells from Primary Tissue
Figure 2 : Drug Development Process
Figure 3 : Average R&D Intensities for Publicly Traded U.S. Companies, by Industry
Figure 4 : Global Pharmaceutical R&D Spending, 2010-2019
Figure 5 : Cellular Models Development Process
Figure 6 : Personalized Medicines Contribution in Total FDA Approvals
Figure 7 : Cell and Gene Therapy Pipeline, by Phase
Figure 8 : Facts About Animals in Research
Figure 9 : Global Market for Primary Cells, by Biological Source Type, 2019-2027
Figure 10 : Global Market Shares of Primary Cells, by Biological Source Type, 2021
Figure 11 : Blood Tissues and Isolated Cells
Figure 12 : Hematopoiesis/Blood Cell Development
Figure 13 : Functions of the Human Liver
Figure 14 : Applications of Primary Hepatocytes in Drug Discovery and Development
Figure 15 : Global Market for Primary Cells, by Tissue Source Type, 2019-2027
Figure 16 : Global Market Shares of Primary Cells, by Tissue Source Type, 2021
Figure 17 : Global Oncology Launches of Novel Active Substances, 2014-2021
Figure 18 : Clinical Trials Started from 2016 to 2021, by Condition
Figure 19 : Global Market for Primary Cells, by End User Type, 2019-2027
Figure 20 : Global Market Shares of Primary Cells, by End User Type, 2021
Figure 21 : Research Applications for Primary Cells
Figure 22 : Primary Cells vs. Immortalized Cell Lines in Drug Discovery Research
Figure 23 : Global Market for Primary Cells, by Application Type, 2019-2027
Figure 24 : Global Market Shares of Primary Cells, by Application Type, 2021
Figure 25 : Publications Referencing Cell Therapy, 2015-2021
Figure 26 : Global Market for Primary Cells, by Region, 2019-2027
Figure 27 : Global Market Shares of Primary Cells, by Region, 2021
Figure 28 : Business Expenditures on Pharmaceutical R&D and Government Budgets for Health-related R&D, 2018 (or nearest year)
Figure 29 : North American Market for Primary Cells, by Tissue Source Type, 2019-2027
Figure 30 : North American Market Shares of Primary Cells, by Tissue Source Type, 2021
Figure 31 : North American Primary Cells Market, by Country, 2019-2027
Figure 32 : CIHR Fiscal Year Investments, by Primary Theme, 2017-2020
Figure 33 : European Market for Primary Cells, by Tissue Source Type, 2019-2027
Figure 34 : European Market Shares of Primary Cells, by Tissue Source Type, 2021
Figure 35 : European Primary Cells Market, by Country, 2019-2027
Figure 36 : European Countries' Gross Domestic Spending on R&D, 2017-2019
Figure 37 : Asia-Pacific Market for Primary Cells, by Tissue Source Type, 2019-2027
Figure 38 : Asia-Pacific Market Shares of Primary Cells, by Tissue Source Type, 2021
Figure 39 : Asia-Pacific Primary Cells Market, by Country, 2019-2027
Figure 40 : RoW Market for Primary Cells, by Tissue Source Type, 2019-2027
Figure 41 : RoW Market Shares of Primary Cells, by Tissue Source Type, 2021
Figure 42 : Charles River Laboratories: Annual Revenue, 2019-2021
Figure 43 : Charles River Laboratories: Revenue Share, by Region/Country, 2021
Figure 44 : Charles River Laboratories' RMS Business Segment: Annual Revenue, 2019-2021
Figure 45 : Lonza: Annual Revenue, 2019-2021
Figure 46 : Lonza: Revenue Share, by Region, 2021
Figure 47 : Lonza's Cell & Gene Division: Annual Revenue, 2019-2021
Figure 48 : Merck KGaA's Life Science Segment: Annual Revenue, 2019-2021
Figure 49 : Merck KGaA's Life Science Segment: Revenue Share, by Business Unit, 2021
Figure 50 : Thermo Fisher Scientific: Annual Revenue, 2019-2021
Figure 51 : Thermo Fisher Scientific: Revenue Share, by Region, 2021
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