Global DNA Sequencing: Research, Applied and Clinical Markets
Market Research Report I 2024-12-13 I 168 Pages I BCC Research
Description
Report Scope
The report highlights the current and future market potential of DNA sequencing and provides a detailed analysis of market drivers, restraints and opportunities. The report also gives market projections for 2029 and includes a competitive environment and product analysis. The report provides market estimates and forecasts for DNA sequencing based on technology, product & service, end user, application, disease category, and region. By technology, the market is segmented into next-generation sequencing (NGS), third-generation sequencing (TGS), pyrosequencing, and Sanger sequencing. By product and service, the market is categorized into instruments and consumables or services. By end user, the market is segmented into academic and research institutes, hospitals and clinics, pharmaceutical and biotechnology companies, contract research organizations, and others. By application, the market is categorized as biopharma, microbiology, agriculture, or others. By disease category, the market is segmented into cancer, reproductive health, Mendelian disorders, and others. The report includes the company profiles of the key players, with detailed information about their business segments, financials, product portfolios, and recent developments.
By geographical region, the market has been segmented into North America, Europe, Asia-Pacific, and the Rest of the World (RoW). The North American region includes the U.S., Canada and Mexico. Europe includes Germany, the U.K., Italy, France, Spain, and the Rest of Europe; Asia-Pacific includes China, Japan, India, Australia, South Korea, and the Rest of Asia-Pacific. For market estimates, data has been provided for 2021 and 2022 as the historic years and for 2023 as the base year, with forecasts through 2029.
Report Includes
- 70 data tables and 59 additional tables
- An overview of the global market for DNA sequencing technologies and their applications in research, applied and clinical segments
- Analysis of the global market trends, with data from 2021-2023, estimates for 2024, and projections of compound annual growth rates (CAGRs) through 2029
- A market forecast for the DNA sequencing industry, and a corresponding market share analysis by products and services, end-use segment, application, disease category and region
- A look at the key market dynamics for DNA sequencing, and the regulatory scenario
- Discussion of market opportunities for DNA sequencing, industry structure, applications and business considerations of sequencing technologies, along with the ongoing changes in the structure of the MedTech industry
- Review of the leading next-generation sequencing (NGS) technologies, emerging applications, and the DNA sequencing-based diagnostics and research initiatives affecting the market
- Analysis of patents related to novel sequencing technologies, as well as clinical trials
- A discussion of ESG challenges and ESG practices in the industry
- Insights into the major acquisitions and strategic alliances, competitive benchmarking of sequencing industry participants and their growth strategies
- Market share analysis of the leading companies, as well as company profiles, including Illumina Inc., Thermo Fisher Scientific Inc., Pacific Biosciences (PacBio), and Oxford Nanopore Technologies Ltd.
Executive Summary
Summary:
In 2023, the global market for DNA sequencing was valued at $12.5 billion. The market is forecast to grow at a CAGR of 18.6% to reach $34.8 billion by the end of 2029.
Technological advances in sequencing techniques and rising applications of DNA sequencing in clinical diagnostics drive the market's growth. The high cost of DNA sequencing, data interpretation and management difficulties challenge the market's growth.
Instruments and consumables held the largest share of the market segmented by product and service in 2023, and this segment is expected to grow at a CAGR of 18.8% during the forecast period. The instruments and consumables segment is further categorized into sequencing instruments, sequencing kits and reagents, and others based on workflow. Services are also further categorized into sequencing services and software and informatics solutions.
In terms of technology, the NGS segment is forecast to grow at a CAGR of 18.9% during the forecast period. This segment accounted for 73.6% of the market in 2023 and is expected to reach a value of $25.9 billion by the end of 2029.
The biopharma segment accounted for 44.8% of the market by application in 2023. This segment is expected to grow at a CAGR of 19.0% during the forecast period, reaching a value of $15.9 billion by the end of 2029.
North America held the largest share of the market by region, with 46.9%, in 2023. Increasing R&D activities and the growing number of regional service providers are responsible for the region's high share.
Table of Contents
Chapter 1 Executive Summary
Market Outlook
Scope of Report
Market Insights
Chapter 2 Market Overview
Importance of DNA
Genetic Variation and Analysis
History of Sequencing
NGS (Second-generation Sequencing)
TGS (Long-read Sequencing)
Research and Applied Applications
R&D Applications
Applied Applications
Direct to Consumer
Biopharma
Agriculture
Forensics
Microbiome
Synthetic Biology
Chapter 3 Market Dynamics
Market Dynamics Snapshot
Market Drivers
Technological Advances in Sequencing Techniques
Rising Applications of DNA Sequencing in Clinical Diagnostics
Market Restraints
High Cost of DNA Sequencing
Data Interpretation and Management Challenges
Market Opportunities
Expansion of Precision Medicine
Growth in NIPT
Chapter 4 Emerging Technologies
Long-read Sequencing Technologies
SMRT Sequencing
Nanopore Sequencing
Spatial Genomics and Transcriptomics
Single-cell DNA Sequencing
Ultra-low Input Sequencing
CRISPR-Cas9 and Genome-editing Integration with Sequencing Technologies
AI and Machine Learning in DNA Sequencing
Chapter 5 Market Segmentation Analysis
Segmentation Breakdown
Global DNA Sequencing Market Analysis by Product and Service
Instruments and Consumables
Services
Global DNA Sequencing Market Analysis by Technology
NGS
TGS
Sanger Sequencing
Pyrosequencing
Global DNA Sequencing Market Analysis by Application
Biopharma
Microbiology
Agriculture
Others (Synthetic Biology, Population Genomics, and Consumer Genomics)
Global DNA Sequencing Market Analysis by End User
Market Size and Forecast
Academic and Research Institutes
Hospitals and Clinics
Pharmaceutical and Biotechnology Companies
Clinical Research
Others (Agricultural Institutions, Forensic Labs)
Global DNA Sequencing Market Analysis by Disease Category
Market Size and Forecast
Cancer
Reproductive Health
Mendelian Disorders
Others (Cardiology, Metabolic/Immune, Neurology, Transplant, Clinical)
Geographic Breakdown
Global DNA Sequencing Market Analysis by Region
Market Size and Forecast
North America
Europe
Asia-Pacific
Rest of the World (RoW)
Chapter 6 Competitive Landscape
Overview
Partnerships
Investments and Funding
Patent Analysis
Chapter 7 ESG Perspective
Introduction
ESG Performance in the Market
ESG Practices in the DNA Sequencing Industry
Environmental Performance
Social Performance
Governance Performance
ESG Risk Ratings in the DNA Sequencing Industry
Concluding Remarks from BCC Research
Chapter 8 Appendix
Methodology
Sources
Abbreviations
Company Profiles
AGILENT TECHNOLOGIES INC.
BGI
F. HOFFMANN-LA ROCHE LTD.
GUARDANT HEALTH
ILLUMINA INC.
MYRIAD GENETICS INC.
OXFORD NANOPORE TECHNOLOGIES PLC.
PACBIO
QIAGEN
THERMO FISHER SCIENTIFIC INC.
Other Key Companies Offering DNA Sequencing Services
10X GENOMICS
CROWN BIOSCIENCE
EUROFINS GENOMICS
GENEWIZ, FROM AZENTA LIFE SCIENCES
INTEGRATED DNA TECHNOLOGIES, INC
MACROGEN
NOVOGENE CO., LTD.
REVVITY
List of Tables
Summary Table : Global DNA Sequencing Market, by Region, Through 2029
Table 1 : DNA Chemical Building Blocks
Table 2 : DNA Transcription and Translation
Table 3 : Long-range DNA Structure
Table 4 : Types of Genetic Variation
Table 5 : Molecular Diagnostic Technology Platforms
Table 6 : Genome Coverage of PCR, Microarray, and NGS Technology Platforms
Table 7 : DNA Sequencing Historical Timeline, 1970s to Present
Table 8 : Main Sequencing Applications
Table 9 : Genetic Analysis Platform Comparison
Table 10 : Sequencing Impact on Agricultural Product Classes
Table 11 : Key Applications in Forensics/Human Identity Sequencing
Table 12 : Key Applications in Microbial Sequencing
Table 13 : Global DNA Sequencing Market, by Product and Service, Through 2029
Table 14 : DNA Sequencing Instruments and Consumables Offered by Major Companies
Table 15 : Global DNA Sequencing Market for Instruments and Consumables, by Region, Through 2029
Table 16 : Global DNA Sequencing Market for Instruments and Consumables, by Workflow Component, Through 2029
Table 17 : Classification of Sequencing Instruments Based on Capacity, Sequencing Capabilities, Read Length, and Application
Table 18 : Global DNA Sequencing Market for Instruments, by Region, Through 2029
Table 19 : Global DNA Sequencing Market for Kits and Reagents, by Region, Through 2029
Table 20 : Global DNA Sequencing Market for Services, by Region, Through 2029
Table 21 : Global DNA Sequencing Market for Services, by Workflow Component, Through 2029
Table 22 : Global DNA Sequencing Market for Services, by Region, Through 2029
Table 23 : Global DNA Sequencing Market for Software and Informatics Solutions, by Region, Through 2029
Table 24 : Global DNA Sequencing Market, by Technology, Through 2029
Table 25 : Global NGS Market, by Region, Through 2029
Table 26 : Different Generations of NGS platforms
Table 27 : Global TGS Market, by Region, Through 2029
Table 28 : Global Sanger Sequencing Market, by Region, Through 2029
Table 29 : Global Pyrosequencing Market, by Region, Through 2029
Table 30 : Global DNA Sequencing Market, by Application, Through 2029
Table 31 : Global DNA Sequencing Market in Biopharma, by Region, Through 2029
Table 32 : Global DNA Sequencing Market in Microbiology, by Region, Through 2029
Table 33 : Global DNA Sequencing Market in Agriculture, by Region, Through 2029
Table 34 : Global DNA Sequencing Market in Other Applications (Synthetic Biology, Population Genomics, and Consumer Genomics), by Region, Through 2029
Table 35 : Global DNA Sequencing Market, by End User, Through 2029
Table 36 : Global DNA Sequencing Market for Academic and Research Institutes, by Region, Through 2029
Table 37 : Global DNA Sequencing Market for Hospitals and Clinics, by Region, Through 2029
Table 38 : Global DNA Sequencing Market for Pharmaceutical and Biotechnology Companies, by Region, Through 2029
Table 39 : Global DNA Sequencing Market for Clinical Research, by Region, Through 2029
Table 40 : Key Applications in Forensics/Human Identity Sequencing
Table 41 : Global DNA Sequencing Market for Other End Users, by Region, Through 2029
Table 42 : Global DNA Sequencing Market, by Disease Category, Through 2029
Table 43 : Global DNA Sequencing Market for Cancer, by Region, Through 2029
Table 44 : Global DNA Sequencing Market for Reproductive Health, by Region, Through 2029
Table 45 : Global DNA Sequencing Market for Mendelian Disorders, by Region, Through 2029
Table 46 : Global DNA Sequencing Market for Other Diseases, by Region, Through 2029
Table 47 : Global DNA Sequencing Market, by Region, Through 2029
Table 48 : North American DNA Sequencing Market, by Country, Through 2029
Table 49 : North American DNA Sequencing Market, by Product and Service, Through 2029
Table 50 : North American DNA Sequencing Market for Instruments and Consumables, by Workflow Component, Through 2029
Table 51 : North American DNA Sequencing Market for Services, by Workflow Component, Through 2029
Table 52 : North American DNA Sequencing Market, by Technology, Through 2029
Table 53 : North American DNA Sequencing Market, by Application, Through 2029
Table 54 : North American DNA Sequencing Market, by End User, Through 2029
Table 55 : North American DNA Sequencing Market, Category, Through 2029
Table 56 : European DNA Sequencing Market, by Country, Through 2029
Table 57 : European DNA Sequencing Market, by Product and Service, Through 2029
Table 58 : European DNA Sequencing Market for Instruments and Consumables, by Workflow Component, Through 2029
Table 59 : European DNA Sequencing Market for Services, by Workflow Component, Through 2029
Table 60 : European DNA Sequencing Market, by Technology, Through 2029
Table 61 : European DNA Sequencing Market, by Application, Through 2029
Table 62 : European DNA Sequencing Market, by End User, Through 2029
Table 63 : European DNA Sequencing Market, by Disease Category, Through 2029
Table 64 : Asia-Pacific DNA Sequencing Market, by Country, Through 2029
Table 65 : Asia-Pacific DNA Sequencing Market, by Product and Service, Through 2029
Table 66 : Asia-Pacific DNA Sequencing Market for Instruments and Consumables, by Workflow Component, Through 2029
Table 67 : Asia-Pacific DNA Sequencing Market for Services, by Workflow Component, Through 2029
Table 68 : Asia-Pacific DNA Sequencing Market, by Technology, Through 2029
Table 69 : Asia-Pacific DNA Sequencing Market, by Application, Through 2029
Table 70 : Asia-Pacific DNA Sequencing Market, by End User, Through 2029
Table 71 : Asia-Pacific DNA Sequencing Market, by Disease Category, Through 2029
Table 72 : RoW DNA Sequencing Market, by Product and Service, Through 2029
Table 73 : RoW DNA Sequencing Market for Instruments and Consumables, by Workflow Component, Through 2029
Table 74 : RoW DNA Sequencing Market for Services, by Workflow Component, Through 2029
Table 75 : RoW DNA Sequencing Market, by Technology, Through 2029
Table 76 : RoW DNA Sequencing Market, by Application, Through 2029
Table 77 : RoW DNA Sequencing Market, by End User, Through 2029
Table 78 : RoW DNA Sequencing Market, by Disease Category, Through 2029
Table 79 : Top DNA Sequencing Companies, 2023
Table 80 : Select Strategic Alliances in the DNA Sequencing Industry, 2022-2024
Table 81 : Major Funding Activities in the DNA Sequencing Industry, 2023 and 2024
Table 82 : Active Patents of Key Competitor Companies, 2024
Table 83 : Key Focus Areas in ESG Metrics
Table 84 : Environmental Performance Initiatives in the DNA Sequencing Market
Table 85 : Social Performance Initiatives in DNA Sequencing Market
Table 86 : Governance Performance Initiatives in DNA Sequencing Market
Table 87 : ESG Rankings for Key Players in DNA Sequencing Market, 2024*
Table 88 : Information Sources in This Report
Table 89 : Abbreviations Used in the DNA Sequencing Market
Table 90 : Agilent Technologies Inc.: Company Snapshot
Table 91 : Agilent Technologies Inc.: Financial Performance, FY 2022 and 2023
Table 92 : Agilent Technologies Inc.: Product Portfolio
Table 93 : Agilent Technologies Inc.: News/Key Developments, 2023
Table 94 : BGI: Company Snapshot
Table 95 : BGI: Financial Performance, FY 2022 and 2023
Table 96 : BGI: Product Portfolio
Table 97 : F. Hoffmann-La Roche Ltd.: Company Snapshot
Table 98 : F. Hoffmann-La Roche Ltd.: Financial Performance, FY 2022 and 2023
Table 99 : F. Hoffmann-La Roche Ltd.: Product Portfolio
Table 100 : F. Hoffmann-La Roche Ltd.: News/Key Developments, 2022-2024
Table 101 : Guardant Health: Company Snapshot
Table 102 : Guardant Health: Financial Performance, FY 2022 and 2023
Table 103 : Guardant Health: Product Portfolio
Table 104 : Guardant Health: News/Key Developments, 2022-2024
Table 105 : Illumina Inc.: Company Snapshot
Table 106 : Illumina Inc.: Financial Performance, FY 2022 and 2023
Table 107 : Illumina Inc.: Product Portfolio
Table 108 : Illumina Inc.: News/Key Developments, 2023 and 2024
Table 109 : Myriad Genetics Inc.: Company Snapshot
Table 110 : Myriad Genetics Inc.: Financial Performance, FY 2022 and 2023
Table 111 : Myriad Genetics Inc.: Product Portfolio
Table 112 : Myriad Genetics Inc.: News/Key Developments, 2023
Table 113 : Oxford Nanopore Technologies plc.: Company Snapshot
Table 114 : Oxford Nanopore Technologies plc.: Financial Performance, FY 2022 and 2023
Table 115 : Oxford Nanopore Technologies plc.: Product Portfolio
Table 116 : Oxford Nanopore Technologies plc.: News/Key Developments, 2024
Table 117 : PacBio: Company Snapshot
Table 118 : PacBio: Financial Performance, FY 2022 and 2023
Table 119 : PacBio: Product Portfolio
Table 120 : PacBio: News/Key Developments, 2023 and 2024
Table 121 : Qiagen: Company Snapshot
Table 122 : Qiagen: Financial Performance, FY 2022 and 2023
Table 123 : Qiagen: Product Portfolio
Table 124 : Qiagen: News/Key Developments, 2023 and 2024
Table 125 : Thermo Fisher Scientific Inc.: Company Snapshot
Table 126 : Thermo Fisher Scientific Inc.: Financial Performance, FY 2022 and 2023
Table 127 : Thermo Fisher Scientific Inc.: Product Portfolio
Table 128 : Thermo Fisher Scientific Inc.: News/Key Developments, 2023 and 2024
List of Figures
Summary Figure : Global DNA Sequencing Market Shares, by Region, 2023
Figure 1 : Evolution of Sequencing Technologies, 1975-2015
Figure 2 : Snapshot of Market Dynamics for DNA Sequencing
Figure 3 : Global DNA Sequencing Market Shares, by Product and Service, 2023
Figure 4 : Global DNA Sequencing Market for Instruments and Consumables, by Region, 2021-2029
Figure 5 : Global DNA Sequencing Market for Services, by Region, 2021-2029
Figure 6 : Global DNA Sequencing Market Shares, by Technology, 2023
Figure 7 : Different NGS Technologies and Their Applications
Figure 8 : Global NGS Market, 2021-2029
Figure 9 : Global NGS Market, by Region, 2021-2029
Figure 10 : Global TGS Market, 2021-2029
Figure 11 : Global TGS Market, by Region, 2021-2029
Figure 12 : Global Sanger Sequencing Market, 2021-2029
Figure 13 : Global Sanger Sequencing Market, by Region, 2021-2029
Figure 14 : Global Pyrosequencing Market, 2021-2029
Figure 15 : Global Pyrosequencing Market, by Region, 2021-2029
Figure 16 : Global DNA Sequencing Market Shares, by Application, 2023
Figure 17 : Global DNA Sequencing Market in Biopharma, 2021-2029
Figure 18 : Global DNA Sequencing Market in Microbiology, 2021-2029
Figure 19 : Global DNA Sequencing Market in Agriculture, 2021-2029
Figure 20 : Global DNA Sequencing Market in Other Applications (Synthetic Biology, Population Genomics, and Consumer Genomics), 2021-2029
Figure 21 : Global DNA Sequencing Market Shares, by End User, 2023
Figure 22 : Global DNA Sequencing Market for Academic and Research Institutes, 2021-2029
Figure 23 : Global DNA Sequencing Market for Hospitals and Clinics, 2021-2029
Figure 24 : Global DNA Sequencing Market for Pharmaceutical and Biotechnology Companies, 2021-2029
Figure 25 : Global DNA Sequencing Market for Clinical Research, 2021-2029
Figure 26 : Global DNA Sequencing Market for Other End Users, 2021-2029
Figure 27 : Global DNA Sequencing Market Shares, by Disease Category, 2023
Figure 28 : Global DNA Sequencing Market for Cancer, 2021-2029
Figure 29 : Global DNA Sequencing Market for Reproductive Health, 2021-2029
Figure 30 : Global DNA Sequencing Market for Mendelian Disorders, 2021-2029
Figure 31 : Global DNA Sequencing Market for Other Diseases, 2021-2029
Figure 32 : Global DNA Sequencing Market Shares, by Region, 2023
Figure 33 : Global DNA Sequencing Market, by Region, 2021-2029
Figure 34 : North American DNA Sequencing Market Shares, by Country, 2023
Figure 35 : The U.S. DNA Sequencing Market, 2021?2029
Figure 36 : Canadian DNA Sequencing Market, 2021?2029
Figure 37 : Mexican DNA Sequencing Market, 2021?2029
Figure 38 : European DNA Sequencing Market Shares, by Country, 2023
Figure 39 : German DNA Sequencing Market, 2021?2029
Figure 40 : The U.K. DNA Sequencing Market, 2021?2029
Figure 41 : French DNA Sequencing Market, 2021?2029
Figure 42 : Italian DNA Sequencing Market, 2021?2029
Figure 43 : Spanish DNA Sequencing Market, 2021?2029
Figure 44 : Rest of European DNA Sequencing Market, 2021?2029
Figure 45 : Asia-Pacific DNA Sequencing Market Shares, by Country, 2023
Figure 46 : Chinese DNA Sequencing Market, 2021?2029
Figure 47 : Japanese DNA Sequencing Market, 2021?2029
Figure 48 : Indian DNA Sequencing Market, 2021?2029
Figure 49 : Australian DNA Sequencing Market, 2021?2029
Figure 50 : South Korean DNA Sequencing Market, 2021?2029
Figure 51 : Rest of Asia-Pacific DNA Sequencing Market, 2021?2029
Figure 52 : Snapshot of ESG Pillars
Figure 53 : Advantages of ESG for Companies
Figure 54 : Share of Biotech Companies Providing ESG Disclosure, 2022
Figure 55 : Share of Biotech Companies Providing ESG Disclosure, by Disclosure Type, 2022
Figure 56 : Agilent Technologies Inc.: Revenue Share, by Business Unit, FY 2023
Figure 57 : Agilent Technologies Inc.: Revenue Share, by Country/Region, FY 2023
Figure 58 : F. Hoffmann-La Roche Ltd.: Revenue Share, by Business Unit, FY 2023
Figure 59 : F. Hoffmann-La Roche Ltd.: Revenue Share, by Country/Region, FY 2023
Figure 60 : Guardant Health: Revenue Share, by Business Unit, FY 2023
Figure 61 : Guardant Health: Revenue Share, by Country/Region, FY 2023
Figure 62 : Illumina Inc.: Revenue Share, by Business Unit, FY 2023
Figure 63 : Illumina Inc.: Revenue Share, by Country/Region, FY 2023
Figure 64 : Myriad Genetics Inc.: Revenue Share, by Business Unit, FY 2023
Figure 65 : Myriad Genetics Inc.: Revenue Share, by Country/Region, FY 2023
Figure 66 : Oxford Nanopore Technologies plc.: Revenue Share, by Business Unit, FY 2023
Figure 67 : Oxford Nanopore Technologies plc.: Revenue Share, by Country/Region, FY 2023
Figure 68 : PacBio: Revenue Share, by Business Unit, FY 2023
Figure 69 : PacBio: Revenue Share, by Country/Region, FY 2023
Figure 70 : Qiagen: Revenue Share, by Business Unit, FY 2023
Figure 71 : Qiagen: Revenue Share, by Country/Region, FY 2023
Figure 72 : Thermo Fisher Scientific Inc.: Revenue Share, by Business Unit, FY 2023
Figure 73 : Thermo Fisher Scientific Inc.: Revenue Share, by Country/Region, FY 2023
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