Complicated Urinary Tract Infections - Market Insight, Epidemiology And Market Forecast - 2032
Market Report I 2022-08-01 I 244 Pages I DelveInsight
DelveInsight's " Complicated Urinary Tract Infection (cUTI) - Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of the Complicated Urinary Tract Infection (cUTI), historical and forecasted epidemiology as well as the Complicated Urinary Tract Infection (cUTI) market trends in the United States, EU-5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
The Complicated Urinary Tract Infection (cUTI) market report provides current treatment practices, emerging drugs, complicated urinary tract infection market share of the individual therapies, current and forecasted complicated urinary tract infection market Size from 2019 to 2032 segmented by seven major markets. The Report also covers current complicated urinary tract infection treatment practice/algorithm, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.
Geography Covered
- The United States
- EU-5 (Germany, France, Italy, Spain, and the United Kingdom)
- Japan
Study Period: 2019-2032
Complicated Urinary Tract Infection (cUTI) Understanding and Treatment Algorithm
The DelveInsight's Complicated Urinary Tract Infection (cUTI) market report gives a thorough understanding of the disease. Urinary tract infections (UTIs) are amongst the most frequent bacterial infections. They can manifest clinically in various ways, from relatively benign, uncomplicated infections to complicated UTIs (cUTIs), pyelonephritis, and severe urosepsis. cUTI is a heterogeneous entity comprising multiple forms.
Several classification systems exist for the description and classification of UTIs, with the common rationale that cUTIs have a higher risk of recurrence or chronification, progression, or severe outcome than uncomplicated UTIs. High antibiotic resistance rates among the causing bacteria are linked to cUTIs and pyelonephritis.
The colonization of the urogenital tract by rectal and perineal flora is the primary cause of UTIs. Escherichia coli, Enterococcus, Klebsiella, Pseudomonas, and other Enterococcus or Staphylococcus species are among the most prevalent microorganisms; the most frequent of them is Escherichia coli, followed by Klebsiella. Candida can colonize individuals receiving residential care, diabetics, those with indwelling catheters, and people with any type of immune impairment.
Patients prone to infection risks tend to get cUTIs more frequently. The likelihood of a cUTI may be increased by the following: age, particularly that of older people and small children, diabetes, renal illness, cancerous bladder blockage, pregnancy with a compromised immune system, and an underlying urologic problem that was recently treated with a catheter.
Despite the frequency of UTIs present in hospitals, they (especially cUTIs) continue to be a clinical entity that causes major confusion, diagnostic ambiguity, and a source of large inappropriate antibiotic prescriptions.
The most crucial clinical criteria for the first diagnosis of a UTI are symptoms, such as increased urinary frequency, urgency, hematuria, dysuria, suprapubic or flank discomfort. Additionally, there must be a suitable clinical scenario in which the most likely cause of these symptoms is an infection of the urogenital tract.
Treatment
First-line antibiotics should be used to begin empiric therapy in this circumstance. Before initiating therapy, a urine sample should be sent for microscopy and culture. Severe cUTIs can present as severe undifferentiated sepsis or even septic shock.
Pharmacotherapy aims to eradicate the infection, prevent complications, and provide symptomatic relief to patients. Early treatment is recommended to reduce the risk of progression to pyelonephritis. The treatment goals are to get rid of the infection, prevent complications, and help provide symptomatic relief. In order to lower the risk of developing pyelonephritis, early treatment is recommended. When considering empirical antimicrobial selection, it is critical to recognize antimicrobial resistance trends. The main course of treatment for individuals with lower UTIs is an oral medication with an empirically selected antibiotic that is effective against Gram-negative aerobic coliform bacteria, such as Escherichia coli. Currently, there are several types of medications used for treatment purposes, namely beta-lactamase inhibitors, protein synthesis inhibitors, and others. At times, combination therapy and dietary supplementation are also prescribed.
Complicated Urinary Tract Infection (cUTI) Epidemiology
The Complicated Urinary Tract Infection epidemiology division provides insights about historical and current Complicated Urinary Tract Infection patient pool and forecasted trends for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This report also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Key Findings
In the year 2021, the total diagnosed incident cases of cUTI were 8.08 Million (M) in the 7MM which are expected to grow during the study period, i.e., 2019-2032.
The disease epidemiology covered in the report provides historical as well as forecasted Complicated Urinary Tract Infection epidemiology [segmented as Total Diagnosed-incident Cases of Complicated Urinary Tract Infection, Total Age-specific Cases of Complicated Urinary Tract Infection, Total Pathogen-specific Cases of Complicated Urinary Tract Infection, and Total Treated Cases (across lines) of Complicated Urinary Tract Infection] in the 7MM covering the United States, EU-5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2019 to 2032.
Country Wise- Complicated Urinary Tract Infection (cUTI) Epidemiology
The epidemiology segment also provides the Complicated Urinary Tract Infection epidemiology data and findings across the United States, EU-5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
According to the DelveInsight, in the year 2021, the total diagnosed incident cases of cUTI were 3.43 M in the United States which are expected to grow during the study period, i.e., 2019-2032.
The highest number of total incident cases of cUTI was observed in Germany among the EU5 countries with 0.87 M cases in 2021 which are expected to grow during the study period, i.e., 2019-2032.
In the year 2021, the total diagnosed incident cases of cUTI were 1.28 M in Japan which are expected to grow during the study period, i.e., 2019-2032.
Complicated Urinary Tract Infection (cUTI) Drug Chapters
The drug chapter segment of the Complicated Urinary Tract Infection report encloses the detailed analysis of Complicated Urinary Tract Infection marketed drugs and late-stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the Complicated Urinary Tract Infection clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.
Emerging Drugs
The report provides the details of the emerging therapies under the late and mid-stage of development for Complicated Urinary Tract Infection treatment.
Complicated Urinary Tract Infection (cUTI) Market Outlook
The Complicated Urinary Tract Infection (cUTI) market outlook of the report helps to build a detailed comprehension of the historic, current, and forecasted Complicated Urinary Tract Infection market trends by analyzing the impact of current therapies on the market, unmet needs, and demand for better technology.
This segment gives a thorough detail of Complicated Urinary Tract Infection market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the Complicated Urinary Tract Infection market in 7MM is expected to witness a major change in the study period 2019-2032.
Key Findings
The Complicated Urinary Tract Infection market size in the 7MM is expected to change during the study period 2019-2032. The therapeutic market of Complicated Urinary Tract Infection in the seven major markets is expected to increase during the study period (2019-2032). In 2021, the total market size of Complicated Urinary Tract Infection was USD 1,868.1 Million which is expected to rise during the study period (2019-2032).
The United States Market Outlook
The total market size of Complicated Urinary Tract Infection in the United States accounted for USD 962.3 M in 2021 which is expected to rise during the study period (2019-2032).
EU-5 Countries: Market Outlook
In EU-5, the total market size of Complicated Urinary Tract Infection was USD 642.0 M in 2021, which is expected to rise during the study period (2019-2032).
Japan Market Outlook
In Japan, the total market size of Complicated Urinary Tract Infection was USD 263.9 M in 2021, which is expected to rise during the study period (2019-2032).
Complicated Urinary Tract Infection (cUTI) Uptake
This section focuses on the rate of uptake of the potential drugs recently launched in the Complicated Urinary Tract Infection market or expected to get launched in the market during the study period 2019-2032. The analysis covers Complicated Urinary Tract Infection market uptake by drugs; patient uptake by therapies; and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs, and allows the comparison of the drugs based on market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Complicated Urinary Tract Infection (cUTI) Development Activities
The report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Complicated Urinary Tract Infection key players involved in developing targeted therapeutics.
Pipeline Development Activities
The report covers detailed information on collaborations, acquisition, and merger, licensing patent details, and other information for Complicated Urinary Tract Infection emerging therapies.
Reimbursement Scenario in Complicated Urinary Tract Infection (cUTI)
Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we consider reimbursement to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.
KOL- Views
To keep up with current market trends, we take KOLs and SMEs ' opinions working in the Complicated Urinary Tract Infection domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies treatment patterns or Complicated Urinary Tract Infection market trends. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the market and the unmet needs.
Competitive Intelligence Analysis
We perform Competitively and Market Intelligence analysis of the Complicated Urinary Tract Infection (cUTI) Market by using various Competitive Intelligence tools that include - SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.
Scope of the Report
- The report covers the descriptive overview of Complicated Urinary Tract Infection, explaining its causes, signs and symptoms, pathophysiology, diagnosis, and currently available therapies
- Comprehensive insight has been provided into the Complicated Urinary Tract Infection epidemiology and treatment in the 7MM
- Additionally, an all-inclusive account of both the current and emerging therapies for Complicated Urinary Tract Infection are provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
- A detailed review of the Complicated Urinary Tract Infection market; historical and forecasted is included in the report, covering drug outreach in the 7MM
- The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Complicated Urinary Tract Infection market.
Report Highlights
- In the coming years, the Complicated Urinary Tract Infection market is set to change due to the upcoming therapies with novel route of administrations which are under investigation and ongoing research in the cUTI; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
- The companies and academics are working to assess challenges and seek opportunities that could influence Complicated Urinary Tract Infection R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition.
- Major players are involved in developing therapies for Complicated Urinary Tract Infection. The launch of emerging therapies will significantly impact the Complicated Urinary Tract Infection market.
- A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Complicated Urinary Tract Infection.
- Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities.
Complicated Urinary Tract Infection (cUTI) Report Insights
- Patient Population
- Therapeutic Approaches
- Complicated Urinary Tract Infection (cUTI) Pipeline Analysis
- Complicated Urinary Tract Infection (cUTI) Market Size and Trends
- Market Opportunities
- Impact of upcoming Therapies
Complicated Urinary Tract Infection (cUTI) Report Key Strengths
- 11 Years Forecast
- 7MM Coverage
- Complicated Urinary Tract Infection (cUTI) Epidemiology Segmentation
- Key Cross Competition
- Highly Analyzed Market
- Drugs Uptake
Complicated Urinary Tract Infection (cUTI) Report Assessment
- Current Treatment Practices
- Unmet Needs
- Pipeline Product Profiles
- Market Attractiveness
Key Questions
Market Insights:
- What was the Complicated Urinary Tract Infection drug class share (%) distribution in 2019 and how it would look like in 2032?
- What would be the Complicated Urinary Tract Infection total market size as well as market size by therapies across the 7MM during the forecast period (2019-2032)?
- What are the key findings of the market across 7MM and which country will have the largest Complicated Urinary Tract Infection market size during the forecast period (2019-2032)?
- At what CAGR, the Complicated Urinary Tract Infection market is expected to grow by 7MM during the forecast period (2019-2032)?
- What would be the Complicated Urinary Tract Infection market outlook across the 7MM during the forecast period (2019-2032)?
- What would be the Complicated Urinary Tract Infection market growth till 2032, and what will be the resultant market Size in the year 2032?
- How would the unmet needs affect the market dynamics and subsequent analysis of the associated trends?
Epidemiology Insights:
- What are the disease risk, burden, and regional/ethnic differences of Complicated Urinary Tract Infection?
- What are the key factors driving the epidemiology trend for seven major markets covering the United States, EU-5 (Germany, Spain, France, Italy, UK), and Japan?
- What is the historical Complicated Urinary Tract Infection patient pool in seven major markets covering the United States, EU-5 (Germany, Spain, France, Italy, UK), and Japan?
- What would be the forecasted patient pool of Complicated Urinary Tract Infection in seven major markets covering the United States, EU-5 (Germany, Spain, France, Italy, UK), and Japan?
- Where will be the growth opportunities in the 7MM concerning the patient population about Complicated Urinary Tract Infection?
- Out of all 7MM countries, which country would have the highest prevalent population of Complicated Urinary Tract Infection during the forecast period (2019-2032)?
- At what CAGR the patient population is expected to grow by 7MM during the forecast period (2019-2032)?
Current Treatment Scenario, Marketed Drugs, and Emerging Therapies:
- What are the current options for the Complicated Urinary Tract Infection treatment in addition to the approved therapies?
- What are the current treatment guidelines for the treatment of Complicated Urinary Tract Infection in the USA, Europe, and Japan?
- What are the Complicated Urinary Tract Infection marketed drugs and their respective MOA, regulatory milestones, product development activities, advantages, disadvantages, safety, efficacy, etc.?
- How many companies are developing therapies for the treatment of Complicated Urinary Tract Infection?
- How many therapies are in-development by each company for Complicated Urinary Tract Infection treatment?
- How many are emerging therapies in mid-stage, and late stage of development for Complicated Urinary Tract Infection treatment?
- What are the key collaborations (Industry - Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Complicated Urinary Tract Infection therapies?
- What are the recent novel therapies, targets, mechanisms of action, and technologies being developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Complicated Urinary Tract Infection and their status?
- What are the current challenges faced in drug development?
- What are the key designations that have been granted for the emerging therapies for Complicated Urinary Tract Infection?
- What are the global historical and forecasted markets of Complicated Urinary Tract Infection?
Reasons to buy
- The report will help in developing business strategies by understanding trends shaping and driving the Complicated Urinary Tract Infection market
- To understand the future market competition in the Complicated Urinary Tract Infection market and Insightful review of the key market drivers and barriers
- Organize sales and marketing efforts by identifying the best opportunities for Complicated Urinary Tract Infection in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom), and Japan
- Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
- Organize sales and marketing efforts by identifying the best opportunities for the Complicated Urinary Tract Infection market
- To understand the future market competition in the Complicated Urinary Tract Infection market
1. Key Insights
2. Report Introduction
3. Table of Contents
4. Complicated Urinary Tract Infection (cUTI) Market Overview at a Glance
4.1. Market Share (%) Distribution of cUTI in 2019
4.2. Market Share (%) Distribution of cUTI in 2032
4.3. Market Share (%) Distribution of Cephalosprin in cUTI by generation in 2019
4.4. Market Share (%) Distribution of Cephalosprin in cUTI by generation in 2032
5. Executive Summary of Complicated Urinary Tract Infection (cUTI)
6. Key Events
6.1. Future Prospectus
7. Epidemiology and Market Methodology
8. Disease Background and Overview
8.1. Introduction
8.2. Classification of UTI
8.3. Signs and Symptoms of cUTIs
8.4. Risk Factors and Causes
8.5. Pathophysiology of cUTIs
8.6. Complications
8.7. Diagnosis of cUTIs
8.7.1. Differential diagnosis (DDx)
8.8. Diagnostic Guidelines for Complicated Urinary Tract Infection
8.8.1. The European Association of Urology Guidelines for Diagnosis of cUTIs
8.8.2. Infectious Diseases Society of America (IDSA) Guidelines for the Diagnosis and Treatment of Asymptomatic Bacteriuria (ASB) in Adults
8.8.3. NICE Guidelines for diagnosis of UTI in infants and children
9. Treatment and Management of cUTIs
9.1.1. Antibiotic resistance in cUTI
9.2. Treatment Guidelines for Complicated Urinary Tract Infection
9.2.1. The European Association of Urology (EAU) Guidelines for Treatment of cUTIs
9.2.2. NICE Guidelines for the management of cUTIs
9.3. Diagnostic and Treatment Algorithm for cUTI
10. Epidemiology and Patient Population
10.1. Key Findings
10.2. Assumptions and Rationale
10.3. Epidemiology Scenario in the 7MM
10.3.1. Total Diagnosed incident Cases of Complicated Urinary Tract Infection (cUTI) in the 7MM
10.3.2. Total Age-specific Cases of Complicated Urinary Tract Infection in the 7MM
10.3.3. Total Pathogen-specific Cases of Complicated Urinary Tract Infection in the 7MM
10.3.4. Total Treated Cases (across lines) of Complicated Urinary Tract Infection in the 7MM
10.4. Epidemiology Scenario in the United States
10.4.1. Total Diagnosed-incident Cases of Complicated Urinary Tract Infection in the US
10.4.2. Total Age-specific Cases of Complicated Urinary Tract Infection
10.4.3. Total Pathogen-specific Cases of Complicated Urinary Tract Infection
10.4.4. Total Treated Cases (across lines) of Complicated Urinary Tract Infection
10.5. Epidemiology Scenario in the EU-5 Countries
10.5.1. Total Diagnosed-incident Cases of Complicated Urinary Tract Infection in EU-5
10.5.2. Total Age-specific Cases of Complicated Urinary Tract Infection in EU-5
10.5.3. Total Pathogen-specific Cases of Complicated Urinary Tract Infection in EU-5
10.5.4. Total Treated Cases (across lines) of Complicated Urinary Tract Infection in EU-5
10.6. Epidemiology Scenario in the Japan
10.6.1. Total Diagnosed-incident Cases of Complicated Urinary Tract Infection (cUTI) in Japan
10.6.2. Total Age-specific Cases of Complicated Urinary Tract Infection in Japan
10.6.3. Total Pathogen-specific Cases of Complicated Urinary Tract Infection in Japan
10.6.4. Total Treated Cases (across lines) of Complicated Urinary Tract Infection in Japan
11. Patient Journey
11.1. Site of Care for patients with cUTI
11.2. Treatment Algorithm of cUTI
11.3. Proportion of patients that are multi-drug resistant & efficacy rate of drugs
11.4. Specialities involved in site of care
12. Marketed Drugs
12.1. Key Competitors
12.2. Recarbrio (imipenem, cilastatin, and relebactam): Merck Sharp & Dohme
12.2.1. Product Description
12.2.2. Regulatory Milestones
12.2.3. Other Developmental Activities
12.2.4. Pivotal Clinical Trial
12.3. Zerbaxa (ceftolozane/tazobactam): Merck Sharp & Dohme
12.3.1. Product Description
12.3.2. Regulatory Milestones
12.3.3. Other Developmental Activities
12.3.4. Pivotal Clinical Trial
12.4. Avycaz (ceftazidime/avibactam): AbbVie/Pfizer
12.4.1. Product Description
12.4.2. Product Description
12.4.3. Regulatory Milestones
12.4.4. Other Developmental Activities
12.5. Pivotal Clinical Trial
12.5.1. Fetroja (cefiderocol): Shionogi
12.5.2. Product Description
12.5.2. Regulatory Milestones
12.5.3. Other Developmental Activities
12.5.4. Pivotal Clinical Trial
12.5.5. Ongoing Current Pipeline Activity
12.6. Vabomere (meropenem/vaborbactam): Melinta Therapeutics
12.6.1. Product Description
12.6.2. Regulatory Milestones
12.6.3. Other Developmental Activities
12.6.4. Pivotal Clinical Trial
12.7. Zemdri (plazomicin): Cipla Therapeutics
12.7.1. Product Description
12.7.2. Regulatory Milestones
12.7.3. Other Developmental Activities
12.7.4. Pivotal Clinical Trial
13. Key Endpoints in Complicated Urinary Tract Infection Clinical Trials
14. Emerging Drugs
14.1. Key Competitors
14.2. Tebipenem Pivoxil Hydrobromide (SPR994): Spero Therapeutics
14.2.1. Product Description
14.2.2. Other Developmental Activities
14.2.3. Clinical Developmental Activities
14.2.4. Safety and Efficacy
14.3. Cefepime-zidebactam (WCK-5222): Wockhardt
14.3.1. Product Description
14.3.2. Other Developmental Activities
14.3.3. Clinical Developmental Activities
14.4. Cefepime/Taniborbactam: Venatorx Pharmaceuticals
14.4.1. Product Description
14.4.2. Other Developmental Activities
14.4.3. Clinical Developmental Activities
14.4.4. Safety and Efficacy
14.5. Cefepime/Enmetazobactam: Allecra Therapeutics
14.5.1. Product Description
14.5.2. Other Developmental Activities
14.5.3. Clinical Developmental Activities
14.5.4. Safety and Efficacy
14.6. Fosfomycin (ZT-01/Contempo): Nabriva Therapeutics AG
14.6.1. Product Description
14.6.2. Other Developmental Activities
14.6.3. Clinical Developmental Activities
14.6.4. Safety and Efficacy
14.7. Finafloxacin: MerLion Pharmaceuticals
14.7.1. Product Description
14.7.2. Other Developmental Activities
14.7.3. Clinical Developmental Activities
14.7.4. Safety and Efficacy
15. Conjoint Analysis
15.1. Key Market Forecast Assumptions
16. Complicated Urinary Tract Infection: 7 Major Market Analysis
16.1. Key Findings
16.2. Market Outlook
16.3. 7MM Market Size
16.3.1. Market Size of Complicated Urinary Tract Infection in the 7MM
16.3.2. Market Size of Complicated Urinary Tract infection by Therapies in the 7MM
16.4. Market Size in the United States
16.4.1. Total Market Size of Complicated Urinary Tract Infection in the United States
16.4.2. Market Size of Complicated Urinary Tract Infection by Therapies in the United States
16.5. Market Size in the EU-5
16.5.1. Total Market size Total Market Size of Complicated Urinary Tract Infection in EU-5
16.5.2. Market Size of Complicated Urinary Tract Infection by Therapies in EU-5
16.6. Japan Market Size
16.6.1. Total Market Size of Complicated Urinary Tract Infection
16.6.2. Market size by Therapies of Complicated Urinary Tract Infection
17. Market Access and Reimbursement
17.1. Key HTA decisions
17.2. Reimbursement
17.3. Patient Access Programs
18. KOL Views
19. SWOT Analysis
20. Unmet Needs
21. Appendix
21.1. Bibliography
21.2. Report Methodology
22. DelveInsight Capabilities
23. Disclaimer
24. About DelveInsight
Table 1: Summary of Complicated Urinary Tract Infection (cUTI), Market, Epidemiology, and Key Events (2019-2032)
Table 2: Organisms commonly found infecting cUTI patients
Table 3: Treatment Regimens for Complicated UTI (known organism and susceptibility)
Table 4: Summary of evidence for the treatment of complicated UTIs
Table 5: Summary of Recommendations for the treatment of complicated UTIs
Table 6: Choice of antibiotic
Table 7: Choice of antibiotic
Table 8: Total Diagnosed-incident Cases of cUTI (in Thousands) in the 7MM(2019-2032)
Table 9: Total Diagnosed-incident Cases of cUTI progressed from uUTI (in Thousands) in the 7MM (2019-2032)
Table 10: Total Age-specific Cases of cUTI (in Thousands) in the 7MM (2019-2032)
Table 11: Total Pathogen-specific Cases of cUTI (in Thousands) in the 7MM (2019-2032)
Table 12: Total Treated Cases of cUTI (in Thousands) in the 7MM (2019-2032)
Table 13: Total Diagnosed-incident Cases of cUTI (in Thousands) in the US (2019-2032)
Table 14: Total Diagnosed-incident Cases of cUTI progressed from uUTI (in Thousands) in the US (2019-2032)
Table 15: Total Age-specific Cases of cUTI (in Thousands) in the US (2019-2032)
Table 16: Total Pathogen-specific Cases of cUTI (in Thousands) in the US (2019-2032)
Table 17: Total Treated Cases of cUTI (in Thousands) in the US (2019-2032)
Table 18: Total Diagnosed-incident Cases of cUTI (in Thousands) in EU-5 (2019-2032)
Table 19: Total Diagnosed-incident Cases of cUTI progressed from uUTI (in Thousands) in EU-5 (2019-2032)
Table 20: Total Age-specific Cases of Complicated Urinary Tract Infection (in Thousands) in EU-5 (2019-2032)
Table 21: Total Pathogen-specific Cases of Complicated Urinary Tract Infection (in Thousands) in EU-5 (2019-2032)
Table 22: Total Treated Cases of cUTI (in Thousands) in EU-5 (2019-2032)
Table 23: Total Diagnosed-incident Cases of cUTI (in Thousands) in Japan (2019-2032)
Table 24: Total Diagnosed-incident Cases of cUTI progressed from uUTI (in Thousands) in Japan (2019-2032)
Table 25: Total Age-specific Cases of cUTI(in Thousands) in Japan(2019-2032)
Table 26: Total Pathogen-specific Cases of cUTI (in Thousands) in Japan(2019-2032)
Table 27: Total Treated Cases of cUTI (in Thousands) in Japan(2019-2032)
Table 28: Antibiotic medications approved for cUTI
Table 29: Treatment Algorithm for cUTI in different site of care settings
Table 30: Percentage of patients suffering from MDR
Table 31: Susceptibility breakpoints (?g/ml) of colistin.
Table 32: Specialities involved in cUTI Treatment
Table 33: Key Competitors
Table 34: In Vitro Susceptibility of Baseline Urine and/or Blood Pathogens (ME Population at DCIV)
Table 35: Composite Microbiological and Clinical Cure Rates in Subgroups Defined by Baseline Pathogen (mMITT population)
Table 36: Microbiological Cure Rate at TOC by Baseline Pathogen from cUTI
Table 37: Microbiological Response Rates by Baseline CAZ-NS Pathogen at the Day 21-25 Visit
Table 38: Composite Endpoint of Microbiological Eradication and Clinical Response at the TOC Visit in cUTI Patients (micro-ITT population) by Baseline Pathogen Subgroups
Table 39: Fetroja (Cefiderocol), Clinical Trial Description, 2022
Table 40: Microbiological Eradication Rate at TOC by Baseline Pathogen in cUTI Patients
Table 41: Key Competitors - Emerging drugs
Table 42: Tebipenem Pivoxil Hydrobromide (SPR994), Clinical Trial Description, 2022
Table 43: Cefepime-zidebactam, Clinical Trial Description, 2022
Table 44: Cefepime/taniborbactam, Clinical Trial Description, 2022
Table 45: Cefepime/Enmetazobactam (AAI101), Clinical Trial Description, 2022
Table 46: Fosfomycin (ZTI-01), Clinical Trial Description, 2022
Table 47: Finafloxacin, Clinical Trial Description, 2022
Table 48: Key Market Forecast Assumptions for Cefepime/taniborbactam
Table 49: Key Market Forecast Assumptions for Cefepime/enmetazobactam
Table 50: Key Market Forecast Assumptions for Tebipenem Pivoxil Hydrobromide
Table 51: Key Market Forecast Assumptions for Cefepime/zidebactam
Table 52: Key Market Forecast Assumptions for Fetroja
Table 53: 7MM Market Size of cUTI in USD Million (2019-2032)
Table 54: 7MM Market Size of Complicated Urinary Tract Infection by Therapies in USD Million (2019-2032)
Table 55: Market Size of Complicated Urinary Tract Infection in the United States, in USD Million (2019-2032)
Table 56: Market Size of cUTI by Therapies in the United States, in USD Million (2019-2032)
Table 57: Market Size of Complicated Urinary Tract Infection in EU-5, in USD Million (2019-2032)
Table 58: Total Market Size of Complicated Urinary Tract Infection by Therapies in EU-5, in USD Million (2019-2032)
Table 59: Total Market Size of Complicated Urinary Tract Infection in Japan, in USD Million (2019-2032)
Table 60: Market Size of Complicated Urinary Tract Infection by Therapies in Japan , in USD Million (2019-2032)
Table 61: Key HTA Decisions
Figure 1: Epidemiology and Market Methodology
Figure 2: Urinary System
Figure 3: Classification of UTI
Figure 4: The European Section of Infections in Urology classification of UTIs
Figure 5: Common Symptoms of UTIs
Figure 6: Pathophysiological aspects of complicated UTI and pyelonephritis
Figure 7: Algorithm for Diagnosis and Treatment of cUTI
Figure 8: Algorithm for evaluating a woman with symptoms of Acute UTI
Figure 9: Total Diagnosed-incident Cases of cUTI in the 7MM (2019-2032)
Figure 10: Total Diagnosed-incident Cases of cUTI progressed from uUTI in the 7MM (2019-2032)
Figure 11: Total Age-specific Cases of cUTI in the 7MM (2019-2032)
Figure 12: Total Pathogen-specific Cases of cUTI in the 7MM (2019-2032)
Figure 13: Total Treated Cases (across the line) of cUTI in the 7MM (2019-2032)
Figure 14: Total Diagnosed-incident Cases of cUTI in the US (2019-2032)
Figure 15: Total Diagnosed-incident Cases of cUTI progressed from uUTI in the US (2019-2032)
Figure 16: Total Age-specific Cases of cUTI in the US (2019-2032)
Figure 17: Total Pathogen-specific Cases of cUTI in the US (2019-2032)
Figure 18: Total Treated Cases (across the line) of cUTI in the US (2019-2032)
Figure 19: Total Diagnosed-incident Cases of cUTI in EU-5 (2019-2032)
Figure 20: Total Diagnosed-incident Cases of cUTI progressed from uUTI in EU-5 (2019-2032)
Figure 21: Total Age-specific Cases of cUTI in EU-5 (2019-2032)
Figure 22: Total Pathogen-specific Cases of Complicated Urinary Tract Infection in EU-5 (2019-2032)
Figure 23: Total Treated Cases (across the line) of cUTI in EU-5 (2019-2032)
Figure 24: Total Diagnosed-incident Cases of cUTI in Japan (2019-2032)
Figure 25: Total Diagnosed-incident Cases of cUTI progressed from uUTI in Japan (2019-2032)
Figure 26: Total Age-specific Cases of cUTI in Japan (2019-2032)
Figure 27: Total Pathogen-specific Cases of cUTI in Japan (2019-2032)
Figure 28: Total Treated Cases (across the line) of cUTI in Japan (2019-2032)
Figure 29: Favorable Response at Discontinuation of IV Therapy in the ME Population (Primary Efficacy Endpoint)
Figure 30: Market Size of cUTI in the 7MM, USD Million (2019-2032)
Figure 31: 7MM Market Size of Complicated Urinary Tract Infection by Therapies in USD Million (2019-2032)
Figure 32: Market Size of Complicated Urinary Tract Infection in the United States, USD Million (2019-2032)
Figure 33: Market Size of Complicated Urinary Tract Infection by Therapies in the United States, in USD Million (2019-2032)
Figure 34: Total Market Size of Complicated Urinary Tract Infection in EU-5, USD Million (2019-2032)
Figure 35: Total Market Size of Complicated Urinary Tract Infection by Therapies in EU-5, in USD Million (2019-2032)
Figure 36: Total Market Size of Complicated Urinary Tract Infection in Japan, in USD Million (2019-2032)
Figure 37: Total Market Size of Complicated Urinary Tract Infection by Therapies in Japan, in USD Million (2019-2032)
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