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Report
Chimeric Antigen Receptor (CAR) T-Cell Therapy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034
Market Report (15 days) I 2024-04-23 I 218 Pages I IMARC Group
The 7 major Chimeric Antigen Receptor (CAR) T-Cell Therapy markets reached a value of US$ 3,589.7 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 11,282.5 Million by 2034, exhibiting a growth rate (CAGR) of 10.85% during 2024-2034.
Chimeric Antigen Receptor (CAR) T-Cell Therapy market is currently driven by factors such as the rising incidence of cancer, a strong drug pipeline, rising number of healthcare settings that administer CAR T, improving safety and efficacy of current and emerging therapies, etc. CAR T-cell therapies have a potential to transform cancer treatment by using the immune system to fight diseases. CAR T therapy requires genetically engineering T cells (either a patient's own or a donor's) to express a chimeric antigen receptor that targets a particular tumor antigen.
The biggest factor catalyzing the growth of the market is the strong efficacy of these treatment. For instance, pediatric and young adult patients with relapsed or refractory Acute Lymphoblastic Leukemia (ALL) achieved an overall remission rate of 90 percent during the first 12 months with treatment with an anti-CD19 autologous CAR T therapy. However, in spite of, the convincing efficacy data in clinical trials, there are a number of challenges impacting the commercialization of CAR Ts. These challenges include complex and costly manufacturing and supply chain, lengthy and logistically challenging patient journey, and reimbursement challenges. The (CAR) T-Cell Therapy market is set to be a transformative therapy in cancer care, but unleashing its potential will require placing strategic bets. Technological advances and manufacturing innovations are rapidly improving - with the prospects for CAR T to not only treat niche liquid tumors but a broader range of solid and liquid tumors in the near future. Market players that are able to make intelligent investments can significantly expand the number of patients they treat as well as the success rates of their therapies.
IMARC Group's new report "Chimeric Antigen Receptor (CAR) T-Cell Therapy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast" provides an exhaustive analysis of the Chimeric Antigen Receptor (CAR) T-Cell Therapy market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. The report provides an in-depth understanding of current and future landscape of the Chimeric Antigen Receptor (CAR) T-Cell Therapy market. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool for Chimeric Antigen Receptor (CAR) T-Cell Therapy across the seven major markets. According to the report the United States has the largest patient pool for Chimeric Antigen Receptor (CAR) T-Cell Therapy and also represents the largest market for Chimeric Antigen Receptor (CAR) T-Cell Therapy treatments. Furthermore, the current Chimeric Antigen Receptor (CAR) T-Cell Therapy treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the Chimeric Antigen Receptor (CAR) T-Cell Therapy market in any manner.
Time Period of the Study
Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034
Countries Covered
United States
Germany
France
United Kingdom
Italy
Spain
Japan
Analysis Covered Across Each Country
Historical, Current and Future Epidemiology Scenario
Historical, Current and Future Performance of the Chimeric Antigen Receptor (CAR) T-Cell Therapy Market
Historical, Current and Future Performance of Various Therapeutic Categories in the Chimeric Antigen Receptor (CAR) T-Cell Therapy Market
Sales of Various Drugs Across the Chimeric Antigen Receptor (CAR) T-Cell Therapy Market
Reimbursement Scenario in the Chimeric Antigen Receptor (CAR) T-Cell Therapy Market
Competitive Landscape:
This report also provides a detailed analysis of the current Chimeric Antigen Receptor (CAR) T-Cell Therapy marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
Late-Stage Pipeline Drugs
Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Key Questions Answered in this Report:
Market Insights
How has the Chimeric Antigen Receptor (CAR) T-Cell Therapy market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to be in 2034?
What was the country-wise size of the Chimeric Antigen Receptor (CAR) T-Cell Therapy market across the seven major markets in 2023 and how will it look like in 2034?
What is the growth rate of the Chimeric Antigen Receptor (CAR) T-Cell Therapy market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the Chimeric Antigen Receptor (CAR) T-Cell Therapy market?
Epidemiology Insights
What is the size of the Chimeric Antigen Receptor (CAR) T-Cell Therapy patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) of Chimeric Antigen Receptor (CAR) T-Cell Therapy across the seven major markets?
What are the key factors driving the epidemiological trend of Chimeric Antigen Receptor (CAR) T-Cell Therapy?
What will be the growth rate of Chimeric Antigen Receptor (CAR) T-Cell Therapy patients across the seven major markets?
Current Treatment Scenario, Marketed Drugs and Emerging Therapies
What are the current marketed Chimeric Antigen Receptor (CAR) T-Cell Therapy drugs and what are their market performance?
What are the key pipeline Chimeric Antigen Receptor (CAR) T-Cell Therapy drugs and how are they expected to perform in the coming years?
How safe are the current marketed Chimeric Antigen Receptor (CAR) T-Cell Therapy drugs and what are their efficacies?
How safe are the late-stage pipeline Chimeric Antigen Receptor (CAR) T-Cell Therapy drugs and what are their efficacies?
What are the current treatment guidelines for Chimeric Antigen Receptor (CAR) T-Cell Therapy drugs across the seven major markets?
Who are the key companies in the Chimeric Antigen Receptor (CAR) T-Cell Therapy market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the Chimeric Antigen Receptor (CAR) T-Cell Therapy market?
1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Introduction
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence
5 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Disease Overview
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment
6 Patient Journey
7 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Epidemiology and Patient Population
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (2018-2023)
7.2.2 Epidemiology Forecast (2024-2034)
7.2.3 Epidemiology by Age (?2018-2034?)
7.2.4 Epidemiology by Gender (?2018-2034?)
7.2.5 Diagnosed Cases (?2018-2034?)
7.2.6 Patient Pool/Treated Cases (?2018-2034?)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (2018-2023)
7.3.2 Epidemiology Forecast (2024-2034)
7.3.3 Epidemiology by Age (?2018-2034?)
7.3.4 Epidemiology by Gender (?2018-2034?)
7.3.5 Diagnosed Cases (?2018-2034?)
7.3.6 Patient Pool/Treated Cases (?2018-2034?)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (2018-2023)
7.4.2 Epidemiology Forecast (2024-2034)
7.4.3 Epidemiology by Age (?2018-2034?)
7.4.4 Epidemiology by Gender (?2018-2034?)
7.4.5 Diagnosed Cases (?2018-2034?)
7.4.6 Patient Pool/Treated Cases (?2018-2034?)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (2018-2023)
7.5.2 Epidemiology Forecast (2024-2034)
7.5.3 Epidemiology by Age (?2018-2034?)
7.5.4 Epidemiology by Gender (?2018-2034?)
7.5.5 Diagnosed Cases (?2018-2034?)
7.5.6 Patient Pool/Treated Cases (?2018-2034?)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (2018-2023)
7.6.2 Epidemiology Forecast (2024-2034)
7.6.3 Epidemiology by Age (?2018-2034?)
7.6.4 Epidemiology by Gender (?2018-2034?)
7.6.5 Diagnosed Cases (?2018-2034?)
7.6.6 Patient Pool/Treated Cases (?2018-2034?)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (2018-2023)
7.7.2 Epidemiology Forecast (2024-2034)
7.7.3 Epidemiology by Age (?2018-2034?)
7.7.4 Epidemiology by Gender (?2018-2034?)
7.7.5 Diagnosed Cases (?2018-2034?)
7.7.6 Patient Pool/Treated Cases (?2018-2034?)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (2018-2023)
7.8.2 Epidemiology Forecast (2024-2034)
7.8.3 Epidemiology by Age (?2018-2034?)
7.8.4 Epidemiology by Gender (?2018-2034?)
7.8.5 Diagnosed Cases (?2018-2034?)
7.8.6 Patient Pool/Treated Cases (?2018-2034?)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (2018-2023)
7.9.2 Epidemiology Forecast (2024-2034)
7.9.3 Epidemiology by Age (?2018-2034?)
7.9.4 Epidemiology by Gender (?2018-2034?)
7.9.5 Diagnosed Cases (?2018-2034?)
7.9.6 Patient Pool/Treated Cases (?2018-2034?)
8 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Treatment Algorithm, Guidelines, and Medical Practices
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm
9 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Unmet Needs
10 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Key Endpoints of Treatment
11 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Marketed Products
11.1 List of Chimeric Antigen Receptor (CAR) T-Cell Therapy Marketed Drugs Across the Top 7 Markets
11.1.1 Breyanzi (Lisocabtagene maraleucel) - Juno Therapeutics
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets
11.1.2 Abecma (Idecabtagene vicleucel) - 2seventy bio
11.1.2.1 Drug Overview
11.1.2.2 Mechanism of Action
11.1.2.3 Regulatory Status
11.1.2.4 Clinical Trial Results
11.1.2.5 Sales Across Major Markets
11.1.3 Carvykti (Ciltacabtagene autoleucel) - Janssen Biotech/Nanjing Legend Biotech
11.1.3.1 Drug Overview
11.1.3.2 Mechanism of Action
11.1.3.3 Regulatory Status
11.1.3.4 Clinical Trial Results
11.1.3.5 Sales Across Major Markets
11.1.4 Kymriah (Tisagenlecleucel) - Novartis/University of Pennsylvania
11.1.4.1 Drug Overview
11.1.4.2 Mechanism of Action
11.1.4.3 Regulatory Status
11.1.4.4 Clinical Trial Results
11.1.4.5 Sales Across Major Markets
11.1.5 Tecartus (Brexucabtagene autoleucel) - Kite Pharma
11.1.5.1 Drug Overview
11.1.5.2 Mechanism of Action
11.1.5.3 Regulatory Status
11.1.5.4 Clinical Trial Results
11.1.5.5 Sales Across Major Markets
Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.
12 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Pipeline Drugs
12.1 List of Chimeric Antigen Receptor (CAR) T-Cell Therapy Pipeline Drugs Across the Top 7 Markets
12.1.1 PHE 885-Novartis Pharmaceuticals
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 TT 11-Tessa Therapeutics
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 Descartes 08 - Cartesian Therapeutics
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
12.1.4 Descartes 011 - Cartesian Therapeutics
12.1.4.1 Drug Overview
12.1.4.2 Mechanism of Action
12.1.4.3 Clinical Trial Results
12.1.4.4 Safety and Efficacy
12.1.4.5 Regulatory Status
12.1.5 BCMA-targeted cell therapy - Arcellx
12.1.5.1 Drug Overview
12.1.5.2 Mechanism of Action
12.1.5.3 Clinical Trial Results
12.1.5.4 Safety and Efficacy
12.1.5.5 Regulatory Status
Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.
13. Chimeric Antigen Receptor (CAR) T-Cell Therapy - Attribute Analysis of Key Marketed and Pipeline Drugs
14. Chimeric Antigen Receptor (CAR) T-Cell Therapy - Clinical Trial Landscape
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events
15 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Scenario
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size
15.2.1.1 Market Size (2018-2023)
15.2.1.2 Market Forecast (2024-2034)
15.2.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size by Therapies
15.2.2.1 Market Size by Therapies (2018-2023)
15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
15.3.1 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size
15.3.1.1 Market Size (2018-2023)
15.3.1.2 Market Forecast (2024-2034)
15.3.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size by Therapies
15.3.2.1 Market Size by Therapies (2018-2023)
15.3.2.2 Market Forecast by Therapies (2024-2034)
15.3.3 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size
15.4.1.1 Market Size (2018-2023)
15.4.1.2 Market Forecast (2024-2034)
15.4.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size by Therapies
15.4.2.1 Market Size by Therapies (2018-2023)
15.4.2.2 Market Forecast by Therapies (2024-2034)
15.4.3 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size
15.5.1.1 Market Size (2018-2023)
15.5.1.2 Market Forecast (2024-2034)
15.5.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size by Therapies
15.5.2.1 Market Size by Therapies (2018-2023)
15.5.2.2 Market Forecast by Therapies (2024-2034)
15.5.3 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size
15.6.1.1 Market Size (2018-2023)
15.6.1.2 Market Forecast (2024-2034)
15.6.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size by Therapies
15.6.2.1 Market Size by Therapies (2018-2023)
15.6.2.2 Market Forecast by Therapies (2024-2034)
15.6.3 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size
15.7.1.1 Market Size (2018-2023)
15.7.1.2 Market Forecast (2024-2034)
15.7.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size by Therapies
15.7.2.1 Market Size by Therapies (2018-2023)
15.7.2.2 Market Forecast by Therapies (2024-2034)
15.7.3 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size
15.8.1.1 Market Size (2018-2023)
15.8.1.2 Market Forecast (2024-2034)
15.8.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size by Therapies
15.8.2.1 Market Size by Therapies (2018-2023)
15.8.2.2 Market Forecast by Therapies (2024-2034)
15.8.3 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size
15.9.1.1 Market Size (2018-2023)
15.9.1.2 Market Forecast (2024-2034)
15.9.2 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Market Size by Therapies
15.9.2.1 Market Size by Therapies (2018-2023)
15.9.2.2 Market Forecast by Therapies (2024-2034)
15.9.3 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Access and Reimbursement Overview
16 Chimeric Antigen Receptor (CAR) T-Cell Therapy - Recent Events and Inputs From Key Opinion Leaders
17 Chimeric Antigen Receptor (CAR) T-Cell Therapy Market - SWOT Analysis
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats
18 Chimeric Antigen Receptor (CAR) T-Cell Therapy Market - Strategic Recommendations
19 Appendix
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