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Report
2024 DNA and RNA Synthesis Research Review
Market Research Report I 2025-03-20 I 184 Pages I BCC Research
Description
Research Review Scope
DNA and RNA synthesis artificially manufactures deoxyribose nucleic acid (DNA) and ribonucleic acid (RNA). Developing synthetic techniques to construct DNA and RNA has improved the ability to understand and engineer biology. Different types of synthesized DNA, such as oligonucleotides, genes, and DNA and RNA fragments, are available and can be utilized per the customer's needs. Synthetic DNA and RNA are used to develop new drugs and vaccines, gene therapies for genetic disorders, and the development of molecular diagnostic tools, including polymerase chain reaction (PCR) assays and nucleic-acid-based sensors, to detect pathogens and diseases.
DNA and RNA synthesis technology is vital in scientific fields such as synthetic biology, molecular genetics, and bioengineering, creating custom DNA and RNA sequences for various research, diagnostic, and therapeutic applications. The rapid expansion of genomics research, advancements in therapeutic DNA and RNA applications, and the growing need for personalized medicine are driving exceptional growth in the DNA & RNA synthesis market. The innovations in CRISPR, gene therapy, and synthetic biology show that the demand for DNA and RNA synthesis has risen sharply, positioning it as a pivotal tool in developing targeted treatments and innovative genetic research solutions.
Research Reviews from BCC Research provide market professionals with concise market coverage within a specific research category. This 2024 Research Review of DNA and RNA synthesis technology provides a sampling of the type of quantitative market information, analysis, and guidance that BCC Research has been developing since its inception in 1971 to help its customers make informed business decisions. This Research Review includes highlights and excerpts from the following reports published by BCC Research in 2024:
- BIO259A Gene Editing Therapeutics Market
- BIO045J Global DNA Sequencing: Research Applied and Clinical Markets
- BIO126E Next-generation Sequencing: Emerging Clinical Applications and Global Markets
- BIO147B RNA Sequencing: Technologies and Global Markets
- BIO127C RNAi Technologies and Global Markets
- BIO192B Viral Vector and Plasmid DNA: Technologies and Global Markets
After you survey the excerpts in this Research Review, we encourage you to follow up on these topics by checking out the full market research reports associated with each topic. BCC Research looks forward to serving your market intelligence needs in the future.
Executive Summary
Summary:
- The global market for DNA sequencing is expected to grow from $14.8 billion in 2024 and is projected to reach $34.8 billion by the end of 2029, at a compound annual growth rate (CAGR) of 18.6% during the forecast period of 2024 to 2029.
- The global market for clinical applications of next-generation sequencing is estimated to increase from $21.9 billion in 2023 to reach $52.9 billion by 2028, at a CAGR of 19.3% from 2023 through 2028.
- The global market for RNA sequencing is expected to grow from $4.3 billion in 2024 and is projected to reach $10.3 billion by the end of 2029, at a CAGR of 19.1% during the forecast period of 2024 to 2029.
DNA and RNA synthesis artificially manufactures deoxyribose nucleic acid (DNA) and ribonucleic acid (RNA). Developing synthetic techniques to construct DNA and RNA has improved the ability to understand and engineer biology. Different types of synthesized DNA, such as oligonucleotides, genes, and DNA and RNA fragments, are available and can be utilized per the customer's needs. Synthetic DNA and RNA are used to develop new drugs and vaccines, gene therapies for genetic disorders, and the development of molecular diagnostic tools, including polymerase chain reaction (PCR) assays and nucleic-acid-based sensors, to detect pathogens and diseases.
DNA and RNA synthesis technology is vital in scientific fields such as synthetic biology, molecular genetics, and bioengineering, creating custom DNA and RNA sequences for various research, diagnostic, and therapeutic applications. The rapid expansion of genomics research, advancements in therapeutic DNA and RNA applications, and the growing need for personalized medicine are driving exceptional growth in the DNA & RNA synthesis market. The innovations in CRISPR, gene therapy, and synthetic biology show that the demand for DNA and RNA synthesis has risen sharply, positioning it as a pivotal tool in developing targeted treatments and innovative genetic research solutions.
Table of Contents
Chapter 1 Foreword
Research Review Scope
Chapter 2 Gene Editing Therapeutics Market (BIO259A)
Scope of Report of Gene Editing Therapeutics
Market Outlook of Gene Editing Therapeutics
Market Summary
Market Overview of Gene Editing Therapeutics
Genome-Editing Tool Types
Meganucleases
Zinc Finger Nucleases
Transcription Activator-like Effector Nucleases
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-Associated Protein 9
Gene editing Therapeutics
Market Dynamics of Gene Editing Therapeutics
Market Driver
Market Challenges
Emerging Technologies and Opportunities of Gene Editing Therapeutics
Base Editing
Prime Editing
Cas-Clover and Cas-FOKl
CRISPR Interference and CRISPR Activation
RNA Editing
Artificial Intelligence in Genome Editing
Market Analysis of Gene Editing Therapeutics
Overview
Casgevy
Market of Gene Editing Therapeutics by Region
North America
Europe
Emerging Markets
ESG Performance in Gene Editing Therapeutics Market
ESG Practices in the Gene Editing Companies
Concluding Remarks from BCC Research
Chapter 3 Global DNA Sequencing: Research, Applied and Clinical Markets (BIO045J)
Scope of Report of DNA Sequencing: Research, Applied and Clinical Markets
Market Outlook of DNA Sequencing: Research, Applied and Clinical Markets
Market Summary of DNA Sequencing: Research, Applied and Clinical Markets
Market Overview of DNA Sequencing: Research, Applied and Clinical Markets
Importance of DNA
Genetic Variation and Analysis
NGS (Second-generation Sequencing)
TGS (Long-read Sequencing)
Research and Applied Applications
R&D Applications
Applied Applications
Direct to Consumer
Biopharma
Agriculture
Forensics
Microbiome
Synthetic Biology
Market Dynamics of DNA Sequencing: Research, Applied and Clinical Markets
Market Driver
Market Restraint
Emerging Technologies of DNA Sequencing: Research, Applied and Clinical Markets
Long-read Sequencing Technologies
SMRT Sequencing
Nanopore Sequencing
Spatial Genomics and Transcriptomics
Single-cell DNA Sequencing
Ultra-low Input Sequencing
CRISPR-Cas9 and Genome-editing Integration with Sequencing Technologies
AI and Machine Learning in DNA Sequencing
Market Breakdown of DNA Sequencing: Research, Applied and Clinical Markets by Technology
Overview
NGS
TGS
Sanger Sequencing
Pyrosequencing
Market Breakdown of DNA Sequencing: Research, Applied and Clinical Markets by Region
North America
Europe
Asia-Pacific
Rest of the World
ESG Performance in DNA Sequencing Industry
Environmental Performance
Social Performance
Governance Performance
ESG Risk Ratings in the DNA Sequencing Industry
Concluding Remarks from BCC Research
Chapter 4 Next-generation Sequencing: Emerging Clinical Applications and Global Markets (BIO126E)
Scope of Report of Next-generation Sequencing
Market Outlook of Next-generation Sequencing
Market Summary of Next-generation Sequencing
Market Overview of Next-generation Sequencing
Liquid and Tissue Biopsy
Growth Drivers of Clinical NGS
Key Trends
Market Dynamics of Next-generation Sequencing
Market Driver
Market Restraint
Emerging Technologies of Next-generation Sequencing
R&D Initiatives and Programs
1+ Million Genomes
Access to Treatment and Testing (ACTT)
Access to Comprehensive Genomic Profiling Coalition (ACGP)
Africa Pathogen Genomics Initiative
Blood Profiling Atlas
Cancer-ID
Cancer Moon Shots Program
China Precision Medicine Initiative
ClinGen
CTC Trap Consortium
diaRNAgnosis Project
Early Cancer Detection Consortium
EpiFemCare
France Genomic Medicine Plan
Friends of Cancer Research Project
Genomic Medicine Sweden
HCA-Organoid
Human Cell Atlas
Human Immunomics Initiative
Immunomonitor Consortium
Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy Program
Intervene
Liquid Biopsies and Imaging for Improved Cancer Care
Liquid Biopsy-Based Malignant Tumor Early Screening Technology Research and Development Project
Liver Cancer Early Screening Comprehensive Prevention and Control Project
Lung Cancer Genomic Screening Project for Individualized Medicine in Asia
Million Veteran Program
Medical Genome Initiative
MedSeq
Market Breakdown of Next-generation Sequencing by Disease Category
Overview
Market Breakdown of Next-generation Sequencing by Region
North America
Europe
Asia-Pacific
ESG Performance in Next-generation Sequencing Industry
Case Study
BCC Research Viewpoint
Chapter 5 RNA Sequencing: Technologies and Global Markets (BIO147B)
Scope of Report of RNA Sequencing
Market Outlook of RNA Sequencing
Market Summary of RNA Sequencing
Market Overview of RNA Sequencing
Technology Background
Transcriptomics Technologies
RNA Sequencing for Transcriptomics
RNA-Seq Experimental Workflow
Regulatory Landscape of RNA Sequencing
Growth Strategy Recommendations
Market Dynamics of RNA Sequencing
Market Drivers
Market Restraints
Market Opportunity
Emerging Technologies and Developments of RNA Sequencing Market
Single-Cell RNA Sequencing
Other Emerging Single-Cell Technologies
Market Breakdown of RNA Sequencing by Product
Instruments
Tools and Reagents
Software and Services
Market Breakdown of RNA Sequencing by Region
Overview
North America
Europe
Asia-Pacific
Rest of the World
Sustainability in RNA Sequencing Market: ESG Perspective
ESG Practices in the RNA Sequencing Industry
Environmental Performance
Social Performance
Governance Performance
Concluding Remarks from BCC Research
Chapter 6 RNAi Technologies and Global Markets ( BIO127C)
Scope of Report of RNAi Technologies
Market Snapshot of RNAi Technologies
Market Summary of RNAi Technologies
Market Overview of RNAi Technologies
RNA Interference Overview
RNA Interference: Mechanism of Action
Initiation Phase
Effector Phase
Small Interfering RNAs (siRNAs)
MicroRNAs (miRNAs)
Small Hairpin RNAs (shRNAs)
Market Dynamics of RNAi Technologies
Market Drivers
Market Challenges
Emerging Technologies and Opportunities of RNAi Technologies
Therapeutics
Diagnostics
Circulating miRNA Diagnostics for Non-invasive Health Monitoring
Agriculture
Market for RNAi Technology by Technology
Therapeutics
Diagnostics
Reagents and Tools
Agriculture
Market for RNAi Technology by Region
Overview
North America
Europe
Emerging Markets
Sustainability in RNAi Technology Industry: An ESG Perspective
Environmental Initiatives
Social Initiatives
Governance Initiatives
Case Study
Concluding Remarks from BCC
Chapter 7 Viral Vector and Plasmid DNA: Technologies and Global Markets (BIO192B)
Scope of Report of Viral Vector and Plasmid DNA
Market Outlook of Viral Vector and Plasmid DNA
Market Summary of Viral Vector and Plasmid DNA
Market Overview of Viral Vector and Plasmid DNA
Cell and Gene Therapy
Market Dynamics of Viral Vector and Plasmid DNA
Market Driver
Market Challenges
Emerging Technologies and Opportunities of Viral Vector and Plasmid DNA
AI in Viral Vector Production
Doggybone DNA
FRAGment Recycler: A New Technology for Plasmid DNA Synthesis
Market for Viral Vector and Plasmid DNA Technologies by Product Type
Market for Viral Vector and Plasmid DNA Technologies by Application
Market for Viral Vector and Plasmid DNA Technologies by Region
Overview
North America
Europe
Asia-Pacific
Latin America
Rest of the World
Sustainability in the Market for Viral Vector and Plasmid DNA Technologies: An ESG Perspective
Environmental Factors
Social Factors
Governance Factors
ESG Performance Among Major Companies
ESG Performance of Select Companies
Lonza: ESG Performance
Thermo Fisher: ESG Performance
Conclusion
Chapter 8 Appendix
Methodology
Analyst's Credentials
List of Tables
Table 1 : Global Market for Gene Editing Therapeutics, Through 2029
Table 2 : Comparison of Genome-Editing Tools
Table 3 : U.S. Adults Age 50 Years and Older with Multiple Chronic Conditions, 2020-2050
Table 4 : Global Cases and Deaths Due to Various Cancers, 2022
Table 5 : Comparison of Cas9-derived Proteins with Regular SpCas9
Table 6 : Global Market for Gene Editing Therapeutics, Through 2029
Table 7 : Global Market for Gene Editing Therapeutics, by Region, Through 2029
Table 8 : ESG Initiatives/Practices by Various Gene Editing Companies, 2023
Table 9 : ESG Rankings for Companies in the Gene Editing Therapeutics Market, 2023
Table 10 : Global DNA Sequencing Market, by Region, Through 2029
Table 11 : DNA Transcription and Translation
Table 12 : Types of Genetic Variation
Table 13 : Molecular Diagnostic Technology Platforms
Table 14 : Main Sequencing Applications
Table 15 : Genetic Analysis Platform Comparison
Table 16 : Key Applications in Microbial Sequencing
Table 17 : Global DNA Sequencing Market, by Technology, Through 2029
Table 18 : Different Generations of NGS Platforms
Table 19 : Global DNA Sequencing Market, by Region, Through 2029
Table 20 : Environmental Performance Initiatives in the DNA Sequencing Market
Table 21 : Social Performance Initiatives in the DNA Sequencing Market
Table 22 : Governance Performance Initiatives in the DNA Sequencing Market
Table 23 : ESG Rankings for Key Players in DNA Sequencing Market, 2024*
Table 24 : Global Market for Clinical Applications of Next-Generation Sequencing, by Disease Class, Through 2028
Table 25 : Forces Influencing Growth in the Clinical NGS Market
Table 26 : Key Trends in the Clinical NGS Testing Market
Table 27 : Future Challenges in Implementing Clinical NGS
Table 28 : Clinical NGS Research and Development Initiatives and Programs
Table 29 : Global Market for Clinical NGS, by Disease Category, Through 2028
Table 30 : Global Market for Clinical NGS, by Region, Through 2028
Table 31 : Key Focus Areas in ESG Metrics
Table 32 : ESG Rankings for Major Companies in the NGS Arena
Table 33 : Illumina 2030 ESG Targets
Table 34 : Global Market for RNA Sequencing, by Product, Through 2029
Table 35 : Global Market for RNA Sequencing, by Technology, Through 2029
Table 36 : Types of RNAs in Cells
Table 37 : Comparison of Transcriptomics Methods
Table 38 : Functional Elements in Sequencing Adapters
Table 39 : Overview of Illumina's Sequencing Instruments
Table 40 : Cloud Computing Providers for Genomics/RNA-Seq
Table 41 : Global Market for RNA Sequencing, by Region, Through 2029
Table 42 : Research Initiatives Focused on Personalized Medicine in Europe
Table 43 : Key Focus Areas in ESG Metrics
Table 44 : Environmental Performance Initiatives in the RNA Sequencing Market
Table 45 : Social Performance Initiatives in the RNA Sequencing Market
Table 46 : Governance Performance Initiatives in the RNA Sequencing Market
Table 47 : ESG Rankings for Key Players in RNA Sequencing Market, 2024*
Table 48 : Global Market for RNAi Technology, by Technology Type, Through 2029
Table 49 : Cost Comparison of siRNA-approved Drugs and Alternative Therapies
Table 50 : Global Market for RNAi Technology, by Technology Type, Through 2029
Table 51 : RNAi Approved Drugs List
Table 52 : miRNA-based Diagnostic Tools Available in Clinical Settings
Table 53 : Global Market for RNAi Technology, by Region, Through 2029
Table 54 : Key Focus Areas in ESG Metrices
Table 55 : Environmental Initiatives, by Various RNAi Technology Companies
Table 56 : ESG Rankings for Companies in the RNAi Technology Market, 2023
Table 57 : Alnylam's ESG initiatives
Table 58 : Global Market for Viral Vector and Plasmid DNA Technologies, by Product Type, Through 2028
Table 59 : Global Incidence of All Cancers, by WHO Region, 2022-2050
Table 60 : Global Market for Viral Vector and Plasmid DNA Technologies, Through 2028
Table 61 : Global Market for Viral Vector and Plasmid DNA Technologies, by Product Type, Through 2028
Table 62 : Global Market for Viral Vector and Plasmid DNA Technologies, by Application, Through 2028
Table 63 : Global Market for Viral Vector and Plasmid DNA Technologies, by Region, Through 2028
Table 64 : ESG Rankings of Major Companies, 2024*
Table 65 : Lonza: ESG Performance
Table 66 : Thermo Fisher: ESG Performance
List of Figures
Figure 1 : Global Market for Gene Editing Therapeutics, 2021-2029
Figure 2 : Emerging Technologies in the Genome-Editing Therapeutics Market
Figure 3 : Global DNA Sequencing Market Shares, by Region, 2023
Figure 4 : Global Market Shares of DNA Sequencing, by Technology, 2023
Figure 5 : Global DNA Sequencing Market Shares, by Region, 2023
Figure 6 : Global Market for Clinical Applications of Next-Generation Sequencing, by Disease Class, 2020-2028
Figure 7 : Key Sustainable Practices Being Implemented in Research Laboratories
Figure 8 : Global Market for RNA Sequencing, by Product, 2021-2029
Figure 9 : Global Market for RNA Sequencing, by Technology, 2021-2029
Figure 10 : RNA-Seq Experiments for Transcriptomics
Figure 11 : RNA-Seq Experimental Workflow
Figure 12 : Growth Strategy Recommendations: RNA Sequencing Market
Figure 13 : Average Cost Per Genome: Y-o-Y Trend, 2011-2022
Figure 14 : Global Market Shares of RNA Sequencing, by Product, 2024
Figure 15 : Global Market Shares of RNA Sequencing, by Region, 2024
Figure 16 : Growth Drivers in Asia-Pacific RNA Sequencing Market
Figure 17 : Global Market for RNAi Technology, by Technology Type, 2021-2029
Figure 18 : Global Market Shares of RNAi Technology, by Technology Type, 2023
Figure 19 : Global Market for RNAi Technology, by Region, 2021-2029
Figure 20 : Global Market Shares of RNAi Technology, by Region, 2023
Figure 21 : Global Market for Viral Vector and Plasmid DNA Technologies, by Product Type, 2020-2028
Figure 22 : Global Market Shares of Viral Vector and Plasmid DNA Technologies, by Product Type, 2022
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