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South & Central America Pulmonary Arterial Hypertension Market Forecast to 2028 - COVID-19 Impact and Regional Analysis - by Drugs [Endothelin Receptor Antagonists (ERAs), Prostacyclin and Prostacyclin Analogs, sGC Stimulators, and pde-5 Dipsticks], Type (Branded and Generics), Route of Administration (Oral, Intravenous/ subcutaneous, and Inhalational), and Distribution Channel (Hospital Pharmacies and Clinics, Online Pharmacies, and Retail Pharmacies)

Market Report I 2023-02-14 I 128 Pages I The Insight Partners
Discounted by 30% to 2024-06-30

The South & Central America pulmonary arterial hypertension market is expected to grow from US$ 732.27 million in 2022 to US$ 976.75 million by 2028; it is estimated to grow at a CAGR of 4.9% from 2022 to 2028.

Growing Patent Expiration to Offer Lucrative Opportunities for South & Central America Pulmonary Arterial Hypertension Market Growth During Forecast Period

Patent expiry permits generic drugs to enter the market and diversify product offerings. A few patented products are expected to become off-patent in the coming years, which is likely to provide an enormous opportunity for generic formulation companies. Many pharma companies such as finds Care Ratings are already working to develop the generic version of patented products. After patent expiration, generic versions of drugs can become available. While consumers benefit from low prices, losing patent protection can expose pharmaceutical companies to growing competition. Thus, patent expiration is expected to offer an opportunity for generic drug manufacturers to enter a new market. Hence, the growing patent expiration is expected to offer lucrative opportunities for the South & Central America pulmonary arterial hypertension market growth in the coming years.

South & Central America Pulmonary Arterial Hypertension Market Overview

Pulmonary arterial hypertension (PAH) is a rare, progressive disease. As per a study titled "Pulmonary Arterial Hypertension in Brazil: Treatment Patterns and Hospitalization Based on Primary Research," published in December 2020, a survey was conducted with six experts in treating PAH in referential public hospitals. Approximately 1,045 patients were treated by the physicians in the 12 months prior to the survey. Treatment patterns and hospitalization were analyzed by patient's risk stratification. Most physicians (67%) stratified patients by risk. Double therapy was used in 47%, 99%, and 74%, and triple therapy at 0%, 1%, and 26% of the patients in low-risk, intermediate-risk, and high-risk groups, respectively. Healthcare resource utilization was greater in patients with progressed pulmonary arterial hypertension, considering medication or hospitalization needs, indicating that costs were 56% higher. Moreover, schistosomiasis was mentioned as one of the most common subtypes of pulmonary arterial hypertension by the Brazilian registry. Data from referral centers in nonendemic regions indicate that up to 30% of pulmonary arterial hypertension cases may be related to schistosomiasis, with a prevalence of schistosomiasis-associated pulmonary arterial hypertension (Sch-PAH) in 4.6% of PAH patients in the country. According to the study "Basic and associated causes of schistosomiasis-related mortality in Brazil," published in 2021, ~4,168 schistosomiasis-related deaths were recorded between 1999 and 2018, as patients with PAH in the country face several barriers to treatment. Further, the Sociedade Brasileira de Pneumologia e Tisiologia (SBPT, Brazilian Thoracic Association) Pulmonary Circulation Committee, founded in 1996, has been involved in continued education and development of guidelines/recommendations for the management of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension over the years in the country. This committee plans any update on the recommendations for the treatment of pulmonary arterial hypertension in the country. In April 2022, as per an article, the Brazilian defense ministry ordered Viagra pills for troops to treat patients with pulmonary arterial hypertension. In Brazil, PAHaspecific therapies are regulated by a national protocol, formed and published by the Ministry of Health, and funded by the public healthcare system. Currently, few drugs are approved for treating PAH within the Sistema Unico de Saude (SUS, Brazilian Unified Health Care System) in Brazil. The PAHaspecific drugs reimbursed in the country include sildenafil, ambrisentan, and bosentan. Other PAHaspecific drugs, such as selexipag, are approved for usage within the country but are not reimbursed by the national or local government. Thus, as per the above-mentioned factors, the South & Central America pulmonary arterial hypertension market is expected to grow steadily in the country during the forecast period.

South & Central America Pulmonary Arterial Hypertension Market Revenue and Forecast to 2028 (US$ Billion)

South & Central America Pulmonary Arterial Hypertension Market Segmentation

The South & Central America pulmonary arterial hypertension market is segmented on the basis of drugs, type, route of administration, distribution channel, and country.

Based on drugs, the South & Central America pulmonary arterial hypertension market is segmented into endothelin receptor antagonists (ERAs), prostacyclin and prostacyclin analogs, sGC stimulators, and pde-5 dipsticks. In 2022, the prostacyclin and prostacyclin analogs segment registered the largest share in the South & Central America pulmonary arterial hypertension market.

Based on type, the South & Central America pulmonary arterial hypertension market is bifurcated into branded and generics. In 2022, the branded segment registered a larger share in the South & Central America pulmonary arterial hypertension market.

Based on route of administration, the South & Central America pulmonary arterial hypertension market is segmented into oral, intravenous/subcutaneous, and inhalational. In 2022, the oral segment registered the largest share in the South & Central America pulmonary arterial hypertension market.

Based on distribution channel, the South & Central America pulmonary arterial hypertension market is segmented into hospital pharmacies and clinics, online pharmacies, and retail pharmacies. In 2022, the hospital pharmacies and clinics segment registered the largest share in the South & Central America pulmonary arterial hypertension market.

Based on country, the South & Central America pulmonary arterial hypertension market is segmented into Brazil, Argentina, and the Rest of South & Central America. In 2022, Brazil registered the largest share in the South & Central America pulmonary arterial hypertension market.

Bayer AG, Gilead Sciences Inc, GSK Plc, Johnson & Johnson, Lupin Ltd, Novartis AG, Pfizer Inc, and Teva Pharmaceutical Industries Ltd are the leading companies operating in the South & Central America pulmonary arterial hypertension market.

TABLE OF CONTENTS
1. Introduction
1.1 Scope of the Study
1.2 The Insight Partners Research Report Guidance
1.3 Market Segmentation
1.3.1 SAM Pulmonary Arterial Hypertension Market - By Drugs
1.3.2 SAM Pulmonary Arterial Hypertension Market - By Type
1.3.3 SAM Pulmonary Arterial Hypertension Market - By Route of Administration
1.3.4 SAM Pulmonary Arterial Hypertension Market - By Distribution Channel
1.3.5 SAM Pulmonary Arterial Hypertension Market - By Country
2. SAM Pulmonary Arterial Hypertension Market - Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. SAM Pulmonary Arterial Hypertension Market - Market Landscape
4.1 Overview
4.2 SAM PEST Analysis
4.3 Experts Opinion
5. SAM Pulmonary Arterial Hypertension Market - Key Market Dynamics
5.1 Market Drivers
5.1.1 Growing Incidence of Pulmonary Arterial Hypertension
5.2 Market Restraints
5.2.1 Side Effects of Drugs Used for Treatment of Pulmonary Arterial Hypertension
5.3 Market Opportunities
5.3.1 Availability of Generics at Affordable Costs Due to Growing Patent Expiration
5.4 Future Trend
5.4.1 Rising Clinical Trials for Drugs Development to Treat Pulmonary Arterial Hypertension
5.5 Impact analysis
6. Pulmonary Arterial Hypertension Market - SAM Analysis
6.1 SAM Pulmonary Arterial Hypertension Market Revenue Forecast and Analysis
7. SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 - by Drugs
7.1 Overview
7.2 SAM Pulmonary Arterial Hypertension Market Revenue Share, by Drugs 2021 & 2028 (%)
7.3 Endothelin Receptor Antagonists (ERAs)
7.3.1 Overview
7.3.2 Endothelin Receptor Antagonists (ERAs): SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
7.4 Prostacyclin and Prostacyclin Analogs
7.4.1 Overview
7.4.2 Prostacyclin and Prostacyclin Analogs: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
7.5 SGC Stimulators
7.5.1 Overview
7.5.2 sGC Stimulators: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
7.6 Pde-5 Dipsticks
7.6.1 Overview
7.6.2 Pde-5 Dipsticks: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
8. SAM Pulmonary Arterial Hypertension Market Analysis and Forecasts to 2028 - by Type
8.1 Overview
8.2 SAM Pulmonary Arterial Hypertension Market, by Type 2021 & 2028 (%)
8.3 Branded
8.3.1 Overview
8.3.2 Branded: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
8.4 Generics
8.4.1 Overview
8.4.2 Generics: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
9. SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 - by Route of Administration
9.1 Overview
9.2 SAM Pulmonary Arterial Hypertension Market Revenue Share, by Route of Administration 2021 & 2028 (%)
9.3 Oral
9.3.1 Overview
9.3.2 Oral: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
9.4 Intravenous/ Subcutaneous
9.4.1 Overview
9.4.2 Intravenous/ Subcutaneous: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
9.5 Inhalational
9.5.1 Overview
9.5.2 Inhalational: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
10. SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 - by Distribution Channel
10.1 Overview
10.2 SAM Pulmonary Arterial Hypertension Market Revenue Share, by Distribution Channel 2021 & 2028 (%)
10.3 Hospital Pharmacies and Clinics
10.3.1 Overview
10.3.2 Hospital Pharmacies and Clinics: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
10.4 Online Pharmacies
10.4.1 Overview
10.4.2 Online Pharmacies: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
10.5 Retail Pharmacies
10.5.1 Overview
10.5.2 Retail Pharmacies: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
11. SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 - Country Analysis
11.1 Overview
11.1.2 South & Central America: Pulmonary Arterial Hypertension Market, by Country, 2021 & 2028 (%)
11.1.2.1 Brazil: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
11.1.2.1.1 Overview
11.1.2.1.2 Brazil: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
11.1.2.1.3 Brazil: Pulmonary Arterial Hypertension Market, by Drugs, 2019-2028 (US$ Million)
11.1.2.1.4 Brazil: Pulmonary Arterial Hypertension Market, by Type, 2019-2028 (US$ Million)
11.1.2.1.5 Brazil: Pulmonary Arterial Hypertension Market, by Route of Administration, 2019-2028 (US$ Million)
11.1.2.1.6 Brazil: Pulmonary Arterial Hypertension Market, by Distribution Channel, 2019-2028 (US$ Million)
11.1.2.2 Argentina: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
11.1.2.2.1 Overview
11.1.2.2.2 Argentina: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
11.1.2.2.3 Argentina: Pulmonary Arterial Hypertension Market, by Drugs, 2019-2028 (US$ Million)
11.1.2.2.4 Argentina: Pulmonary Arterial Hypertension Market, by Type, 2019-2028 (US$ Million)
11.1.2.2.5 Argentina: Pulmonary Arterial Hypertension Market, by Route of Administration, 2019-2028 (US$ Million)
11.1.2.2.6 Argentina: Pulmonary Arterial Hypertension Market, by Distribution Channel, 2019-2028 (US$ Million)
11.1.2.3 Rest of SAM: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
11.1.2.3.1 Overview
11.1.2.3.2 Rest of SAM: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
11.1.2.3.3 Rest of SAM: Pulmonary Arterial Hypertension Market, by Drugs, 2019-2028 (US$ Million)
11.1.2.3.4 Rest of SAM: Pulmonary Arterial Hypertension Market, by Type, 2019-2028 (US$ Million)
11.1.2.3.5 Rest of SAM: Pulmonary Arterial Hypertension Market, by Route of Administration, 2019-2028 (US$ Million)
11.1.2.3.6 Rest of SAM: Pulmonary Arterial Hypertension Market, by Distribution Channel, 2019-2028 (US$ Million)
12. SAM Pulmonary Arterial Hypertension Market - Industry Landscape
12.1 Overview
12.2 Organic Developments
12.2.1 Overview
12.3 Inorganic Developments
12.3.1 Overview
13. Company Profiles
13.1 Johnson & Johnson
13.1.1 Key Facts
13.1.2 Business Description
13.1.3 Products and Services
13.1.4 Financial Overview
13.1.5 SWOT Analysis
13.1.6 Key Developments
13.2 Gilead Sciences Inc
13.2.1 Key Facts
13.2.2 Business Description
13.2.3 Products and Services
13.2.4 Financial Overview
13.2.5 SWOT Analysis
13.2.6 Key Developments
13.3 Bayer AG
13.3.1 Key Facts
13.3.2 Business Description
13.3.3 Products and Services
13.3.4 Financial Overview
13.3.5 SWOT Analysis
13.3.6 Key Developments
13.4 Novartis AG
13.4.1 Key Facts
13.4.2 Business Description
13.4.3 Products and Services
13.4.4 Financial Overview
13.4.5 SWOT Analysis
13.4.6 Key Developments
13.5 GSK Plc
13.5.1 Key Facts
13.5.2 Business Description
13.5.3 Products and Services
13.5.4 Financial Overview
13.5.5 SWOT Analysis
13.5.6 Key Developments
13.6 Teva Pharmaceutical Industries Ltd
13.6.1 Key Facts
13.6.2 Business Description
13.6.3 Products and Services
13.6.4 Financial Overview
13.6.5 SWOT Analysis
13.6.6 Key Developments
13.7 Lupin Ltd
13.7.1 Key Facts
13.7.2 Business Description
13.7.3 Products and Services
13.7.4 Financial Overview
13.7.5 SWOT Analysis
13.7.6 Key Developments
13.8 Pfizer Inc
13.8.1 Key Facts
13.8.2 Business Description
13.8.3 Products and Services
13.8.4 Financial Overview
13.8.5 SWOT Analysis
13.8.6 Key Developments
14. Appendix
14.1 About The Insight Partners
14.2 Glossary of Terms

LIST OF TABLES
Table 1. SAM: Pulmonary Arterial Hypertension Market, by Type - Revenue and Forecast to 2028 (US$ Million)
Table 2. Brazil: Pulmonary Arterial Hypertension Market, by Drugs - Revenue and Forecast to 2028 (US$ Million)
Table 3. Brazil: Pulmonary Arterial Hypertension Market, by Type - Revenue and Forecast to 2028 (US$ Million)
Table 4. Brazil: Pulmonary Arterial Hypertension Market, by Route of Administration- Revenue and Forecast to 2028 (US$ Million)
Table 5. Brazil: Pulmonary Arterial Hypertension Market, by Distribution Channel - Revenue and Forecast to 2028 (US$ Million)
Table 6. Argentina: Pulmonary Arterial Hypertension Market, by Drugs - Revenue and Forecast to 2028 (US$ Million)
Table 7. Argentina: Pulmonary Arterial Hypertension Market, by Type - Revenue and Forecast to 2028 (US$ Million)
Table 8. Argentina: Pulmonary Arterial Hypertension Market, by Route of Administration- Revenue and Forecast to 2028 (US$ Million)
Table 9. Argentina: Pulmonary Arterial Hypertension Market, by Distribution Channel - Revenue and Forecast to 2028 (US$ Million)
Table 10. Rest of SAM: Pulmonary Arterial Hypertension Market, by Drugs - Revenue and Forecast to 2028 (US$ Million)
Table 11. Rest of SAM: Pulmonary Arterial Hypertension Market, by Type - Revenue and Forecast to 2028 (US$ Million)
Table 12. Rest of SAM: Pulmonary Arterial Hypertension Market, by Route of Administration- Revenue and Forecast to 2028 (US$ Million)
Table 13. Rest of SAM: Pulmonary Arterial Hypertension Market, by Distribution Channel - Revenue and Forecast to 2028 (US$ Million)
Table 14. Organic Developments in the SAM pulmonary arterial hypertension market
Table 15. Inorganic Developments in the SAM pulmonary arterial hypertension market
Table 16. Glossary of Terms


LIST OF FIGURES
Figure 1. SAM Pulmonary Arterial Hypertension Market Segmentation
Figure 2. SAM Pulmonary Arterial Hypertension Market - By Country
Figure 3. SAM Pulmonary Arterial Hypertension Market Overview
Figure 4. Prostacyclin and Prostacyclin Analogs Segment Held Largest Share by Drugs of the SAM Pulmonary Arterial Hypertension Market
Figure 5. Brazil to Show Significant Growth During Forecast Period
Figure 6. SAM: PEST Analysis
Figure 7. Experts Opinion
Figure 8. SAM Pulmonary Arterial Hypertension Market Impact Analysis of Drivers and Restraint
Figure 9. SAM Pulmonary Arterial Hypertension Market- Revenue Forecast and Analysis - 2020 - 2028
Figure 10. SAM Pulmonary Arterial Hypertension Market Revenue Share, by Drugs 2021 & 2028 (%)
Figure 11. Endothelin Receptor Antagonists (ERAs): SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 12. Prostacyclin and Prostacyclin Analogs: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 13. sGC Stimulators: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 14. Pde-5 Dipsticks: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 15. SAM Pulmonary Arterial Hypertension Market, by Type 2021 & 2028 (%)
Figure 16. Branded: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 17. Generics: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 18. SAM Pulmonary Arterial Hypertension Market Revenue Share, by Route of Administration 2021 & 2028 (%)
Figure 19. Oral: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 20. Intravenous/ Subcutaneous: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 21. Inhalational: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 22. SAM Pulmonary Arterial Hypertension Market Revenue Share, by Distribution Channel 2021 & 2028 (%)
Figure 23. Hospital Pharmacies and Clinics: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 24. Online Pharmacies: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 25. Retail Pharmacies: SAM Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 26. South & Central America: Pulmonary Arterial Hypertension Market, by Key Country - Revenue (2021) (US$ Million)
Figure 27. South & Central America: Pulmonary Arterial Hypertension Market, by Country, 2021 & 2028 (%)
Figure 28. Brazil: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 29. Argentina: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)
Figure 30. Rest of SAM: Pulmonary Arterial Hypertension Market - Revenue and Forecast to 2028 (US$ Million)

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